New genetic test for mouth cancer
Thursday 04 October 2012
A new genetic test has been developed that can detect early signs of mouth cancer.
The qMIDS test measures the activity of 16 genes from a piece of biopsy tissue less than half the size of a grain of rice.
It can show whether patients with mouth sores or ulcers possess pre-cancerous cells.
The test had a cancer detection rate of up to 94% when used on more than 350 head and neck tissue specimens from 299 patients in the UK and Norway.
Mouth, or oral cancer, affects more than 6,200 people each year in the UK.
One of the main symptoms is mouth lesions, such as sores and ulcers. But these are very common and mostly benign - only 5% to 30% may develop into cancers.
Lead researcher Dr Muy-Teck Teh, from the Institute of Dentistry at Queen Mary, University of London, said: "A sensitive test capable of quantifying a patient's cancer risk is needed to avoid the adoption of a 'wait-and-see' intervention.
"Detecting cancer early, coupled with appropriate treatment, can significantly improve patient outcomes, reduce mortality, and alleviate long-term public healthcare costs."
The findings are published in the International Journal of Cancer.
Civets have had their day as the mammal behind the world’s most expensive coffee – that accolade now reportedly goes to Thai elephants, the latest animal whose internal systems are being utilised for coffee production.
Life & Style blogs
GTA 5 Online DLC: San Andreas Flight School update brings 16-seater jet plane and more
What is ALS and the Ice Bucket Challenge?
David Beckham fronts the campaign for his underwear autumn/winter collection, which hit stores today
London restaurant 34 creates champagne glass modelled on Kate Moss’ left breast
NHS patients to be seen by 'doctors on the cheap'
- 1 Jeremy Clarkson 'sees no problem' with his racist language on Top Gear, says BBC
- 2 Richard Dawkins on babies with Down Syndrome: 'Abort it and try again – it would be immoral to bring it into the world'
- 3 London restaurant 34 creates champagne glass modelled on Kate Moss’ left breast
- 4 ALS ice bucket challenge co-founder Corey Griffin drowns, aged 27
- 5 James Foley beheading: Fox news presenter Megyn Kelly annoyed by Ferguson update during broadcast about murdered journalist
£40000 - £50000 Per Annum: The Green Recruitment Company: The Green Recruitmen...
Competitive: The Green Recruitment Company: Job Title: Structural Engineer Job...
£25000 - £28000 per annum: Ashdown Group: Generalist HR Administrator - Tunbri...
£45000 - £50000 per annum + 5 weeks holiday & benefits: Ashdown Group: Head of...