Nice approves prostate cancer drug Abirateron

 

A drug to treat advanced prostate cancer should be given to patients on the NHS, a health watchdog has said.

Abirateron, marketed as Zytiga, can extend the lives of late-stage cancer sufferers by more than three months.

The National Institute for Health and Clinical Excellence (Nice) revised its recommendations after fresh information from manufacturer Janssen, and the new draft guidance was welcomed by experts.

Professor Alan Ashworth, chief executive of the Institute of Cancer Research, said: "We are delighted by today's decision to allow patients with advanced prostate cancer to receive abiraterone on the NHS.

"This drug was discovered at the Institute of Cancer Research and is the result of more than two decades of dedicated work by our scientists and collaborators.

"In clinical trials of men with advanced prostate cancer who have already tried chemotherapy, it has been shown to extend life by an average of four months and improve quality of life."

Each year around 37,000 men in the UK are diagnosed with prostate cancer and 10,000 die from the disease. It is the second most common cause of cancer death in men, accounting for 13 per cent.

Sir Andrew Dillon, chief executive of Nice, said: "During the consultation on the draft guidance Janssen, the manufacturer of the drug, submitted further information for the committee to consider.

"This included a revised patient access scheme which involves providing the drug to the NHS at a discounted price, further information on which patients would benefit most and clarification on how many patients could receive the drug.

"These factors enabled the committee to revise its preliminary recommendation and now recommend the drug for use on the NHS.

"We are very pleased that Janssen's submission to our consultation means that we are able to produce draft guidance recommending abiraterone - it is an effective treatment, potentially extending life by more than three months, and it also allows patients to be treated at home as it can be taken orally."

As Nice has not issued final guidance there is a chance the decision could be appealed against, and NHS bodies should make decisions locally on the funding of specific treatments.

Nice recommended the use of abiraterone in combination with prednisone or prednisolone for the treatment of castration-resistant metastatic prostate cancer that has progressed after one docetaxel-containing therapy.

The Prostate Cancer Charity also welcomed the recommendation, but called for the guidance to be issued across the whole of the UK - including Scotland - because Nice covers just England and Wales.

Owen Sharp, chief executive of the charity said: "This announcement represents a resounding triumph for each of the thousands of men with advanced prostate cancer in England and Wales who know just how much the prospect of precious extra time with their loved ones really means.

"We are delighted that Nice has overturned its earlier decision after reviewing the evidence. We are also pleased that the manufacturer responded to our call to deliver a further reduction in price.

"Although today marks a very welcome advancement, it has to be remembered that abiraterone remains out of reach to men in Scotland on the NHS.

"We need to see every man who needs this drug receive it on the NHS, regardless of where they live in the UK."

PA

PROMOTED VIDEO
Life and Style
ebookNow available in paperback
Life and Style
ebooksA superb mix of recipes serving up the freshest of local produce in a delicious range of styles
Arts and Entertainment
American singer, acclaimed actor of stage and screen, political activist and civil rights campaigner Paul Robeson (1898 - 1976), rehearses in relaxed mood at the piano.
filmSinger, actor, activist, athlete: Paul Robeson was a cultural giant. But prejudice and intolerance drove him to a miserable death. Now his story is to be told in film...
News
i100
Arts and Entertainment
Babysitter Katie and Paul have terse words in the park
tvReview: The strength of the writing keeps viewers glued to their seats even when they are confronted with the hard-hitting scenes
Life and Style
Make-up artists prepare contestants for last year’s Miss World, held in Budapest
fashion
Life and Style
life
News
‘The Graduate’, starring Dustin Hoffman and Anne Bancroft, was directed by Nichols in his purple period
people
Latest stories from i100
Have you tried new the Independent Digital Edition apps?

ES Rentals

    Independent Dating
    and  

    By clicking 'Search' you
    are agreeing to our
    Terms of Use.

    iJobs Job Widget
    iJobs General

    Argyll Scott International: FP&A Manager Supply Chain

    Benefits: Argyll Scott International: Argyll Scott is recruiting for a Permane...

    Austen Lloyd: Commercial Property NQ+

    £30000 - £50000 per annum + EXCELLENT: Austen Lloyd: COMMERCIAL PROPERTY SOLI...

    Argyll Scott International: Retail Commercial Finance Analyst

    Benefits: Argyll Scott International: Due to further expansion, a leading inte...

    Langley James : Senior Technician; Promotion & Training Opp; Borough; upto £32k

    £27000 - £32000 per annum + training: Langley James : Senior Technician; Promo...

    Day In a Page

    US immigration: President Obama ready to press ahead with long-promised plan to overhaul 'broken system' - but will it get past a Republican-controlled Congress?

    Immigration: Obama's final frontier

    The President is ready to press ahead with the long-promised plan to overhaul America's 'broken system' - but will it get past a Republican-controlled Congress?
    Travelling to work by scooter is faster than walking and less sweaty than cycling, so why aren’t we all doing it?

    Scoot commute

    Travelling to work by scooter is faster than walking and less sweaty than cycling, so why aren’t we all doing it?
    Paul Robeson: The story of how an American icon was driven to death to be told in film

    The Paul Robeson story

    How an American icon was driven to death to be told in film
    10 best satellite navigation systems

    Never get lost again: 10 best satellite navigation systems

    Keep your vehicle going in the right direction with a clever device
    Synagogue attack: Fear unites both sides of Jerusalem as minister warns restoring quiet could take 'months'

    Terror unites Jerusalem after synagogue attack

    Rising violence and increased police patrols have left residents of all faiths looking over their shoulders
    Medecins sans Frontieres: The Ebola crisis has them in the headlines, but their work goes far beyond West Africa

    'How do you carry on? You have to...'

    The Ebola crisis has Medecins sans Frontieres in the headlines, but their work goes far beyond West Africa
    Isis extends its deadly reach with suicide bombing in Kurdish capital

    Isis extends its deadly reach with suicide bombing in Kurdish capital

    Residents in what was Iraq’s safest city fear an increase in jihadist attacks, reports Patrick Cockburn
    Underwater photography competition winners 2014 - in pictures

    'Mysterious and inviting' shot of diver wins photography competition

    Stunning image of cenote in Mexico takes top prize
    Sir John Major: Negative West End portrayals of politicians put people off voting

    Sir John Major hits out at theatres

    Negative West End portrayals of politicians put people off voting
    Kicking Barbie's butt: How the growth of 3D printing enabled me to make an army of custom-made figurines

    Kicking Barbie's butt

    How the growth of 3D printing enabled toy-designer to make an army of custom-made figurines
    Will Smith's children have made waves with a gloriously over-the-top interview, but will their music match their musings?

    What are Jaden and Willow on about?

    Will Smith's children have made waves with a gloriously over-the-top interview, but will their music match their musings?
    Fridge gate: How George Osborne keeping his fridge padlocked shows a frosty side to shared spaces

    Cold war

    How George Osborne keeping his fridge padlocked shows a frosty side to shared spaces
    Stocking fillers: 10 best loo books

    Stocking fillers: 10 best loo books

    From dogs in cars to online etiquette, while away a few minutes in peace with one of these humorous, original and occasionally educational tomes
    Malky Mackay appointed Wigan manager: Three texts keep Scot’s rehabilitation on a knife-edge

    Three texts keep Mackay’s rehabilitation on a knife-edge

    New Wigan manager said all the right things - but until the FA’s verdict is delivered he is still on probation, says Ian Herbert
    Louis van Gaal: the liberal, the enemy and... err, the poet

    Louis van Gaal: the liberal, the enemy and... err, the poet

    ‘O, Louis’ is the plaintive title of a biography about the Dutchman. Ian Herbert looks at what it tells us about the Manchester United manager