Removal of a woman's ovaries 'leads to an increased risk of mental decline in older age'

 

Removal of a woman's ovaries leads to an increased risk of mental decline in older age, a study has found.

The procedure, which triggers a "surgical menopause", is most often carried out on younger women because of cancer. It usually accompanies removal of the womb, or hysterectomy.

Scientists studied 1,837 women aged between 53 and 100, a third of whom had experienced a surgical menopause.

The women were given tests to measure thinking skills and memory. They showed that having a surgical menopause at an earlier age was associated with faster declines in thinking ability and certain kinds of memory.

Long-term memory relating to concepts and ideas and episodic memory of events were both affected.

The findings were presented today at the American Academy of Neurology's annual meeting in San Diego, US.

Lead scientist Dr Riley Bove, from Harvard Medical School in Boston, said the results suggested a potential benefit from hormone replacement therapy.

"While we found a link between surgical menopause and thinking and memory decline, women on longer hormone replacement therapies had slower declines," said study author Riley Bove, MD, with Harvard Medical School in Boston and a member of the American Academy of Neurology.

"Since hormone replacement therapy is widely available, our research raises questions as to whether these therapies have a protective effect against cognitive decline and whether women who experience early surgical menopause should be taking hormone replacement therapies afterward."

A significant association was also seen between age at surgical menopause and the brain deposits linked to Alzheimer's disease.

"Our study warrants further research as the interest in this subject will continue to grow right along with our ageing population," said Dr Bove.

PA

Life and Style
ebookNow available in paperback
ebooks
ebookA delicious collection of 50 meaty main courses
Latest stories from i100
Have you tried new the Independent Digital Edition apps?

ES Rentals

    Independent Dating
    and  

    By clicking 'Search' you
    are agreeing to our
    Terms of Use.

    iJobs Job Widget
    iJobs General

    Recruitment Genius: Trainee Vehicle Inspectors / Purchasers

    £20000 - £40000 per annum: Recruitment Genius: Trainee Vehicle Inspectors / Pu...

    Recruitment Genius: Vehicle Broker / Purchaser

    £18000 - £45000 per annum: Recruitment Genius: This is an exciting opportunity...

    Recruitment Genius: Sales Executive - OTE £45,000

    £18000 - £45000 per annum: Recruitment Genius: A Sales Executive is required t...

    Recruitment Genius: Call Centre Manager - OTE £50,000

    £25000 - £50000 per annum: Recruitment Genius: This innovative online car purc...

    Day In a Page

    Greece debt crisis: EU 'family' needs to forgive rather than punish an impoverished state

    EU 'family' needs to forgive rather than punish an impoverished state

    An outbreak of malaria in Greece four years ago helps us understand the crisis, says Robert Fisk
    Gaza, a year on from Operation Protective Edge: The traumatised kibbutz on Israel's front line, still recovering from last summer's war with Hamas

    Gaza, a year on from Operation Protective Edge

    The traumatised kibbutz on Israel's front line, still recovering from last summer's war with Hamas
    How to survive electrical storms: What are the chances of being hit by lightning?

    Heavy weather

    What are the chances of being hit by lightning?
    World Bodypainting Festival 2015: Bizarre and brilliant photos celebrate 'the body as art'

    World Bodypainting Festival 2015

    Bizarre and brilliant photos celebrate 'the body as art'
    alt-j: A private jet, a Mercury Prize and Latitude headliners

    Don't call us nerds

    Craig Mclean meets alt-j - the math-folk act who are flying high
    How to find gold: The Californian badlands, digging out crevasses and sifting sludge

    How to find gold

    Steve Boggan finds himself in the Californian badlands, digging out crevasses and sifting sludge
    Singing accents: From Herman's Hermits and David Bowie to Alesha Dixon

    Not born in the USA

    Lay off Alesha Dixon: songs sound better in US accents, even our national anthem
    10 best balsamic vinegars

    10 best balsamic vinegars

    Drizzle it over salad, enjoy it with ciabatta, marinate vegetables, or use it to add depth to a sauce - this versatile staple is a cook's best friend
    Greece says 'No': A night of huge celebrations in Athens as voters decisively back Tsipras and his anti-austerity stance in historic referendum

    Greece referendum

    Greeks say 'No' to austerity and plunge Europe into crisis
    Ten years after the 7/7 terror attacks, is Britain an altered state?

    7/7 bombings anniversary

    Ten years after the terror attacks, is Britain an altered state?
    Beautiful evening dresses are some of the loveliest Donatella has created

    Versace haute couture review

    Beautiful evening dresses are some of the loveliest Donatella has ever created
    No hope and no jobs, so Gaza's young risk their lives, climb the fence and run for it

    No hope and no jobs in Gaza

    So the young risk their lives and run for it
    Fashion apps: Retailers roll together shopping and social networking for mobile customers

    Fashion apps

    Retailers roll together shopping and social networking for mobile customers
    The Greek referendum exposes a gaping hole at the heart of the European Union – its distinct lack of any genuine popular legitimacy

    Gaping hole at the heart of the European Union

    Treatment of Greece has shown up a lack of genuine legitimacy
    Number of young homeless in Britain 'more than three times the official figures'

    'Everything changed when I went to the hostel'

    Number of young homeless people in Britain is 'more than three times the official figures'