Warning over second child swine-flu jab
High fever, drowsiness and loss of appetite are side-effects, say regulators
Saturday 05 December 2009
Children having their second dose of the swine flu jab may develop a high fever, European regulators have warned. Parents and doctors are being urged to keep watch on a child's temperature after research found they were more likely to suffer a fever above 38C (100F) after the second dose compared with after the first.
Children were also more likely to suffer soreness at the site of injection as well as drowsiness, irritability and loss of appetite after the second dose. British children under 10 in high-risk groups are being given two 0.25ml doses of the Pandemrix vaccine, half a normal adult dose. The doses are at least three weeks apart.
Experts at the European Medicines Agency (EMEA) said the "findings were unexpected, as they were not seen with the mock-up vaccine". But the Agency said the second dose boosted the child's immune response against swine flu.
More than three million healthy children aged six months to five across the UK will be offered the swine-flu jab after those in high-risk groups (such as with asthma, cancer or diabetes) have been inoculated. Pandemrix, made by GlaxoSmithKline, is being given out widely as the main vaccine; Baxter's Celvapan is reserved for people with an egg allergy.
The EMEA said: "Parents and carers of young children (below six) vaccinated with Pandemrix should be aware that fever may occur, and that this fever can be high (above 38C). They should monitor the child's temperature after each vaccination, and give a medicine such as paracetamol to control the fever as necessary.
"But the Agency noted that the second dose increases the immune response against pandemic influenza. The Agency has recommended that this information be included in the prescribing information, and be taken into consideration when deciding whether to give a second dose to children. This follows the review of new GlaxoSmithKline data from an ongoing clinical trial in children aged from six months to three years."
Some 1.6 million doses of the vaccine have been given in England so far, a rise of 600,000 in the past week. The Chief Medical Officer, Sir Liam Donaldson, has said under-fives are suffering particularly badly with swine flu, which can cause trouble with breathing. Under-fives are about three times as likely to end up in hospital with swine flu as those aged 16 to 64. Figures show an estimated 22,000 new cases of swine flu in England in the past week, down 46,000 the week before.
Swedish stars ask fans for £195 pledges on crowd-funding website
musicAs Mariah Carey and Noddy Holder rake in the royalties from their classics, why there hasn't been a decent festive hit for 20 years?
theatreAuthor Daniel Rosenthal recalls the mishaps that almost brought the curtain down on the likes of John Gielgud and Diana Rigg
lifeFull of the joys and want to help your fellow man? December isn't the time to do it
lifeAs the Royal Mail plans to phase out deliveries on two wheels, it's no wonder posties are in a spin
techLuke Blackall reports on precision engineered prams and babygros that monitor your child 24-7
Life & Style blogs
Low-cost metal 3D printer could be the next step in home manufacturing revolution
YouTube: Top trending videos of 2013 - including Tom Daley and Peppa Pig
People who drink alcohol outlive those who abstain, study shows
Exercise most effective lifestyle choice for preventing dementia, researchers say
GTA 5 update: Content Creator released, online heists and story mode updates coming soon
- 1 Nelson Mandela memorial: ‘Bogus’ interpreter made mockery of Barack Obama’s tribute
- 2 It’s shameful that our universities have accepted gender segregation under pressure from the most oppressive religious fanatics
- 3 Kenyan politician Mike Sonko left red-faced after photoshopping himself next to Nelson Mandela
- 4 Exeter to Edinburgh and back in a day: How one fresher's lost bet left him facing a 900-mile round trip
- 5 Selfie at funeral: Cameron squeezes in on Obama snap at Mandela memorial
- < Previous
- Next >
£50000 - £60000 per annum + BONUS + BENEFITS: Harrington Starr: A leading prov...
£70000 - £90000 per annum + BONUS + BENEFITS: Harrington Starr: A leading mark...
£34999 - £44001 per annum + Benefits: Pro-Recruitment Group: A Top 10 Accounta...
£60000 - £80000 per annum + benefits + bonus: Harrington Starr: Product Specia...