High estrogen levels impact brain
Sunday 26 September 2010
High estrogen levels in women while they are ovulating may be directly responsible for sluggishness or problems concentrating, a Canadian study released Friday has found.
Researchers at Concordia University's Center for Studies in Behavioral Neurobiology in Montreal linked high estrogen levels in laboratory rats to an inability to pay attention and learn.
These high levels have also been shown to interfere with women's ability to pay attention, but the study, to be published in the journal Brain and Cognition, is the first to show "how this impediment can be due to a direct effect of the hormone on mature brain structures," said a statement.
Both humans and rodents have similar brain physiology.
"Although estrogen is known to play a significant role in learning and memory, there has been no clear consensus on its effect," said study lead author Wayne Brake.
"Our findings ... show conclusively that high estrogen levels inhibit the cognitive ability in female rodents."
Researchers repeatedly exposed rats to a tone, with no consequences. Once they became used to it and ignored it, another stimulus was linked to the tone.
Rats with low levels of estrogen quickly learned that the tone was associated with the new stimulus whereas those with higher levels of estrogen took longer to form this memory.
"We only observed this effect in adult female rats," Brake said. "This and our other findings indicate that estrogen directly affects the brain, perhaps by interfering with brain signaling molecules."
The next step, he said, will be to determine how this occurs.
Life & Style blogs
iPhone 7 (or iPhone 6S) leaked pictures show similarities to older model — but Apple is fixing the biggest issue of all
People all over the world are getting semicolon tattoos to draw attention to mental health
'Help me I'm trapped in a factory' messages keep being found on bottles of vitamin water
Google has set its terrifying, dreaming image robots on the public
What do the emojis on Snapchat mean?
- 1 Nathan Collier: Montana man inspired by same-sex marriage ruling requests right to wed two wives
- 2 Van driver who comforted Clark Carlisle and called 999 after suicide attempt dies age 24
- 3 People all over the world are getting semicolon tattoos to draw attention to mental health
- 4 Baby rescued 1km out to sea after parents forgot about her
- 5 Greek debt crisis: The photograph that conveys the despair of Greece's elderly
£15000 - £25000 per annum: Recruitment Genius: To support their continued grow...
£22000 - £25000 per annum: Recruitment Genius: They are the go-to company for ...
Negotiable: Recruitment Genius: This is an opportunity to join the UK's leadin...
Negotiable: Recruitment Genius: This caravan dealership are currently recruiti...