Limited node removal may suffice in breast cancer
Wednesday 09 February 2011
A US study published Tuesday suggested that early stage breast cancer patients who have a small amount of lymph node removed fare as well as those who get more extensive surgery.
Researchers examined data from women whose breast cancer had spread to a nearby lymph node and studied survival rates among those who had the first lymph node, or sentinel lymph node, removed compared to those who had lymph nodes from the armpit removed, known as axillary lymph node dissection (ALND).
Their results showed that "do not benefit from the addition of ALND in terms of local control, disease-free survival, or overall survival, and that ALND may no longer be justified for certain patients," the study said.
"Implementation of this practice change would improve clinical outcomes in thousands of women each year by reducing the complications associated with ALND and improving quality of life with no diminution in survival."
The California-based study included 891 patients who were followed from 1999 to 2004.
The limited surgical intervention resulted in five-year overall survival rates of 92.5 percent compared to 91.8 percent among those who had more lymph nodes taken out.
Disease-free survival was also similar across the two groups, with 83.9 percent in the sentinel node group and 82.2 in the group that had more extensive intervention.
The research was published in the Journal of the American Medical Association.
Life & Style blogs
How Stephen Hawking is still alive, defying ALS and the worst expectations
The black and blue dress: Makers considering a white and gold version
More than two thirds of smokers are killed by diseases caused by tobacco use, says study
This is what it's like to be dead, according to a guy who died for a bit
The remarkable archaeological underwater discovery that could open up a new chapter in the study of European and British prehistory
- 2 The black and blue dress: Makers considering a white and gold version
- 3 This is what it's like to be dead, according to a guy who died for a bit
- 4 PornHub turns masturbation into energy in bid to save the planet
£9 per hour: Recruitment Genius: This role is based within a small family run ...
£28000 - £32000 per annum: Recruitment Genius: This Design and marketing agenc...
£46000 per annum: Recruitment Genius: This property investment firm are lookin...
£18000 - £35000 per annum: Recruitment Genius: This company specialises provid...