Cloned lamb sends PPL shares soaring
Tuesday 25 February 1997
Ron James, managing director, described the success with Dolly, which has an identical genetic make-up to its six-year-old "mother", as "a major scientific advance" which would underline PPL's leading position in "transgenic" technology.
"This new breakthrough will open up the possibility for a variety of additional products to be produced economically by PPL. Some of these products could not be produced by existing technology - for example, human serum albumin used in the treatment of burns and other traumatic injury."
PPL was floated on the stock market last year to commercialise a process by which human proteins can be synthesised in large quantities in genetically altered or transgenic animals.
Dolly was the result of work done by PPL's scientists working with the Roslin Institute, near Edinburgh. Roslin, which was established as a government research operation, has agreed to give PPL an exclusive licence for the technology in exchange for undisclosed royalties.
PPL already has a flock of sheep from a transgenic father, created by injecting DNA into an embryo and placing it back in the womb so that the animal is born in the usual way. Dolly has involved taking a cell from a six-year-old "mother" to replace the genetic information in an unfertilised egg.
Alan Colman, PPL's research director, said the cloning process would allow scientists to single out more productive animals. At present five to 10 transgenic sheep have to be created in the hope that one will prove to be a productive animal. The cloning process would eliminate that process, resulting in more cost-efficiency, Mr Colman suggested.
PPL's lead product is Alpha 1 Anti Trypsin or AAT for treating cystic fibrosis, which is currently in early-stage human trials. The proteins used in AAT are milked from the transgenic sheep before processing.
Mr Colman held out the prospect that the new cloning technology could also help deal with currently untreatable diseases such as BSE and scrapie. He suggested that the cells which cause the diseases might be able to be removed from cattle and sheep, making them resistant.
International Women's Day 2014: The shocking statistics that show why it is still so important
Feminist quotes to inspire you on the International Women's Day
Oscar Pistorius trial first week: Never mind a media scrum – murder case becomes bizarre safari following the tracks of a wounded lion
International Women’s Day: 'When a man gives his opinion, he's a man. When a woman gives her opinion, she's a bitch' - feminist quotes from female icons to inspire you
Malaysia Airlines plane: Oil slick is first sign that missing flight crashed into sea killing up to 239 on board
Apple's Tim Cook: Business isn’t just about making profit
Thousands of young people forced to go without food after benefits wrongly stopped under 'draconian' new sanctions regime
Ukraine crisis: New navy chief 'defects' and surrenders Crimean HQ as Putin claims ultranationalists forced intervention
Britain's top vet sparks controversy with call for ban on slashing animals' throats in 'ritual' slaughters for halal and kosher meat products
Ukraine crisis: Russia dismisses '3am ultimatum' as 'total nonsense'
If you're horrified by a flame-roasted dog, you should be shocked at a hog roast
- 1 To those who can’t see the point of International Women’s Day: you are the very reason it exists
- 2 International Women's Day 2014: The shocking statistics that show why it is still so important
- 4 Orgasm machine to deliver climax at the push of a button
iJobs Money & Business
£12000 per annum: Inspiring Interns: The company works with Tier 1 FTSE 100 Ba...
£32000 - £36000 per annum + generous benefits: Pro-Recruitment Group: * TAX * ...
£37000 - £40000 per annum + £20000 benefits package: Pro-Recruitment Group: **...
£30000 - £35000 per annum + generous benefits: Pro-Recruitment Group: Mixed Ta...