Cloned lamb sends PPL shares soaring
Tuesday 25 February 1997
Ron James, managing director, described the success with Dolly, which has an identical genetic make-up to its six-year-old "mother", as "a major scientific advance" which would underline PPL's leading position in "transgenic" technology.
"This new breakthrough will open up the possibility for a variety of additional products to be produced economically by PPL. Some of these products could not be produced by existing technology - for example, human serum albumin used in the treatment of burns and other traumatic injury."
PPL was floated on the stock market last year to commercialise a process by which human proteins can be synthesised in large quantities in genetically altered or transgenic animals.
Dolly was the result of work done by PPL's scientists working with the Roslin Institute, near Edinburgh. Roslin, which was established as a government research operation, has agreed to give PPL an exclusive licence for the technology in exchange for undisclosed royalties.
PPL already has a flock of sheep from a transgenic father, created by injecting DNA into an embryo and placing it back in the womb so that the animal is born in the usual way. Dolly has involved taking a cell from a six-year-old "mother" to replace the genetic information in an unfertilised egg.
Alan Colman, PPL's research director, said the cloning process would allow scientists to single out more productive animals. At present five to 10 transgenic sheep have to be created in the hope that one will prove to be a productive animal. The cloning process would eliminate that process, resulting in more cost-efficiency, Mr Colman suggested.
PPL's lead product is Alpha 1 Anti Trypsin or AAT for treating cystic fibrosis, which is currently in early-stage human trials. The proteins used in AAT are milked from the transgenic sheep before processing.
Mr Colman held out the prospect that the new cloning technology could also help deal with currently untreatable diseases such as BSE and scrapie. He suggested that the cells which cause the diseases might be able to be removed from cattle and sheep, making them resistant.
- 1 What happens to your body when you give up sugar?
- 2 Have sex with your iPad thanks to the new sex toy no-one asked for
- 3 The 'sex selfie stick' lets you FaceTime the inside of a vagina
- 4 Why you're almost certainly more like your father than your mother
- 5 Westboro Baptist Church couldn't picket Leonard Nimoy's funeral because they didn't know where it was
Mark Zuckerberg: Facebook CEO's one simple test for who to hire
Bali nine: Welcome to 'Execution Island' – the Indonesian holiday resort where foreigners are sent to die
'A girl is more responsible for rape than a boy': The statement that shocked the world... except India
The 'sex selfie stick' lets you FaceTime the inside of a vagina
Saudi Arabia executions now at 'unprecedented rate' after kingdom kills four more in two days
Durham Free School: 'Creationism taught at' free school facing closure
Nearly 100,000 of Britain's poorest children go hungry after parents' benefits are cut
End of the licence fee: BBC to back radical overhaul of how it is funded
Nigel Farage promises Ukip will not 'stigmatise' would-be migrants – and says he wants 'everyone to speak the same language'
Ex-head of MI6: 'We shouldn't kid ourselves that Russia is on a path to democracy'
Most people think legal tax avoidance is just as wrong as illegal tax evasion, poll suggests
iJobs Money & Business
£8 per hour: Recruitment Genius: This Pension Specialist was established early...
£30 - 35k + Bonus & Benefits: Guru Careers: We are seeking an Executive Assist...
£25000 - £30000 per annum + benefits: Ashdown Group: A global leader operating...
Voluntary post, reasonable expenses reimbursed: Reach Volunteering: Would you ...