Inner-ear hair cells offer hope for hard of hearing
Thursday 28 August 2008
The delicate hair cells of the inner ear that are crucial to hearing have been grown successfully in mice for the first time by scientists who believe that the technique may one day be used to restore hearing in profoundly deaf people.
Many problems with hearing are due to defective auditory hair cells, which mammals cannot normally regenerate. In humans, hair cells are naturally lost during a lifetime, causing a corresponding loss of hearing with age. So being able to grow them by a form of gene therapy raises the prospect of being able to treat deafness in a radically different way.
The scientists stimulated the growth of new hair cells in the inner ear of the mice by transferring a key gene into the cochlea – the auditory part of the inner ear – triggering the development of the fine, sensory cells that respond to sound waves of different frequencies.
The study, printed in the journal Nature, was carried out on mice embryos in the womb. "This is just the first step," said John Brigande of the Oregon Health and Science University in Portland, Oregon. "We need to learn if we can restore hearing in deaf mice by gene transfer."
- 1 Gun instructor accidentally shot dead by nine-year-old girl with Uzi gun
- 2 Miley Cyrus' homeless MTV VMAs date, Jesse Helt, is wanted by the police
- 5 Homer Simpson has taken the ALS ice bucket challenge because of course he has
Kensington flat branded ‘uninhabitable’ by estate agent on sale for a bargain £600,000
Gun instructor accidentally shot dead by nine-year-old girl with Uzi gun
Miley Cyrus' homeless MTV VMAs date, Jesse Helt, is wanted by the police
Notting Hill Carnival: Woman shares selfie after being ‘punched in face for telling man to stop groping her’
The 13 obscure UK laws you didn’t know you were breaking
Exclusive: We share blame for creating 'jihad generation', says Muslim strategist
Robin Williams Emmys tribute led by Billy Crystal criticised for including 'racist' joke about Muslim woman
The Rotherham child abuse scandal is a tale of apologists, misogyny and double standards
Scottish independence TV debate: Pumped-up Alex Salmond bounces back in bruising second round against Alistair Darling
Jeremy Clarkson is a cultural tumour and needs to be removed, says comedian Frankie Boyle
Do you realise just how foolish the UK looks?
- < Previous
- Next >
£40000 - £48000 per annum + benefits+bonus+package: Harrington Starr: C# Devel...
£45000 - £60000 per annum + benefits+bonus+package: Harrington Starr: C# Swift...
£55000 - £70000 per annum + Benefits + Bonus: Harrington Starr: Front-End Deve...
£30000 - £40000 per annum + Benefits + Bonus: Harrington Starr: Graduate C# De...