DJ Dave Lee Travis has been charged with 11 counts of indecent assault and one of sexual assault against alleged victims aged between 15 and 29.
The 68-year-old, whose real name is David Patrick Griffin, is accused of committing the offences between 1977 and 2007, the Crown Prosecution Service said.
Travis, from Bedfordshire, has consistently maintained his innocence since he was first arrested in November. Travis was re-arrested after further allegations emerged in March.
After his arrest over the additional allegations, he said: "The last four months have been extraordinary. Allegations which I strongly deny have been put to me by the police and to which I have given full and complete answers. I have fully co-operated and my conscience is clear."
He was charged as part of Operation Yewtree, the police investigation prompted by the Jimmy Savile abuse scandal, but the accusations against Travis have no connection to the disgraced television presenter.
Chief Crown Prosecutor for CPS London, Alison Saunders, said: "We have carefully considered the evidence gathered by the Metropolitan Police Service as part of Operation Yewtree in relation to David Patrick Griffin, who was initially arrested on November 15 2012 over allegations of sexual offences.
"Having completed our review, we have concluded that there is sufficient evidence and it is in the public interest for Mr Griffin to be charged with 11 counts of indecent assault and one of sexual assault. These date from 1977 to 2007 and relate to nine complainants aged between 15 and 29 at the time of the alleged offending."
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