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A huge explosion has rocked the rebel-held city of Donetsk in eastern Ukraine, smashing windows over a radius of several kilometres and sending a vast mushroom cloud up into the sky.
The blast occurred at a rubber processing factory full of chemicals, with numerous videos taken in the aftermath of the initial explosion showing further, smaller bursts of flame.
The plant lies in a rebel-controlled area on the outskirts of the city, the largest controlled by the pro-Russian separatists. They and government forces are supposed to be in a state of ceasefire after agreeing a truce last month, but diminished artillery exchanges have continued.
Today's blast, which rang out at 12.15pm local time, was described by witnesses as by far the largest to have occurred in Donetsk for some time.
Some rebels said it was caused by a tactical SS-21 Scarab missile, according to Russian media outlets, though this could not be independently verified.
A spokesperson for the Ukrainian military denied reports that the explosion was caused by one of its missiles, saying Kiev's forces had nothing to do with the incident.
Pictures showed damage to the exterior of the Donbass Arena, home to the football club Shakhtar Donetsk, while video released by rebels showed a meeting of the Donetsk People's Republic interrupted by the loud blast, shaking the building and causing attendants to panic.
Ukraine crisis: A timeline of the conflictShow all 23 1 /23Ukraine crisis: A timeline of the conflict Ukraine crisis: A timeline of the conflict 30 November 2013 Public support grows for the “Euromaidan” anti-government protesters in Kiev demonstrating against Yanukovych’s refusal to sign the EU Association Agreement as images of them injured by police crackdown spread.
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Ukraine crisis: A timeline of the conflict 20 February 2014 Kiev sees its worst day of violence for almost 70 years as at least 88 people are killed in 48 hours, with uniformed snipers shooting at protesters from rooftops.
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Ukraine crisis: A timeline of the conflict 22 February 2014 Yanukovych flees the country after protest leaders and politicians agree to form a new government and hold elections. The imprisoned former Prime Minister, Yulia Tymoshenko, is freed from prison and protesters take control of Presidential administration buildings, including Mr Yanukovych's residence.
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Ukraine crisis: A timeline of the conflict 27 February 2014 Pro-Russian militias seize government buildings in Crimea and the new Ukrainian government vows to prevent the country breaking up as the Crimean Parliament sets a referendum on secession from Ukraine in May.
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Ukraine crisis: A timeline of the conflict 16 March 2014 Crimea votes overwhelmingly to secede from Ukraine and join Russia in a ballot condemned by the US and Europe as illegal. Russian troops had moved into the peninsula weeks before after pro-Russian separatists occupied buildings.
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Ukraine crisis: A timeline of the conflict 6 April 2014 Pro-Russian rebels seize government buildings in the eastern cities of Donetsk, Luhansk and Kharkiv, calling for a referendum on independence and claiming independent republic. Ukraine authorities regain control of Kharkiv buildings on 8 April after launching an “anti-terror operation” but the rest remain out of their control.
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Ukraine crisis: A timeline of the conflict 7 June 2014 Petro Poroshenko is sworn in as Ukraine's president, calling on separatists to lay down their arms and end the fighting and later orders the creation of humanitarian corridors, since violated, to allow civilians to flee war zones.
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Ukraine crisis: A timeline of the conflict 27 June 2014 The EU signs an association agreement with Ukraine, along with Georgia and Moldova, eight months after protests over the abandonment of the deal sparked the crisis.
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Ukraine crisis: A timeline of the conflict 17 July 2014 Malaysian Airlines flight MH17 is shot down over eastern Ukraine, killing all 298 people on board. Ukrainian intelligence officials claim it was hit by rebels using a Buk surface-to-air launcher in an apparent accident.
Ukraine crisis: A timeline of the conflict 22 August 2014 A Russian aid convoy of more than 100 lorries enters eastern Ukraine and makes drop in rebel-controlled Luhansk without Government permission, sparking allegations of a “direct violation of international law”.
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Ukraine crisis: A timeline of the conflict 29 August 2014 Nato releases satellite images appearing to show Russian soldiers, artillery and armoured vehicles engaged in military operations in eastern Ukraine.
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Ukraine crisis: A timeline of the conflict 8 September 2014 Russia warns that it could block flights through its airspace if the EU goes ahead with new sanctions over the ongoing crisis and conflict
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Ukraine crisis: A timeline of the conflict 17 September 2014 Despite the cease-fire and a law passed by the Ukrainian parliament on Tuesday granting greater autonomy to rebel-held parts of the east, civilian casualties continued to rise, adding to the estimated 3,000 people killed
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Ukraine crisis: A timeline of the conflict 20 October 2014 A 'tactical missile' explosion at a factory sends blast wave across rebel-held cityof Donetsk
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Ukraine crisis: A timeline of the conflict 16 November 2014 The fragile ceasefire gives way to an increased wave of military activity as artillery fire continues to rock the eastern Ukraine's pro-Russian rebel bastion of Donetsk
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Ukraine crisis: A timeline of the conflict 26 December 2014 A new round of ceasefire talks, scheduled on neutral ground in the Belariusian capital Minsk, are called off
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Ukraine crisis: A timeline of the conflict 12 January 2015 Soldiers in Debaltseve were forced to prepare heavy defences around the city; despite a brief respite to the fighting in eastern Ukraine, hostilities in Donetsk resumed at a level not seen since September 2014
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Ukraine crisis: A timeline of the conflict 21 January 2015 13 people are killed during shelling of bus in the rebel-held city of Donetsk
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Ukraine crisis: A timeline of the conflict 24 January 2015 Ten people were killed after pro-Russian separatists bombarded the east Ukrainian port city of Mariupol
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Ukraine crisis: A timeline of the conflict 2 February 2015 There was a dangerous shift in tempo as rebels bolstered troop numbers against government forces
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Ukraine crisis: A timeline of the conflict 11 February 2015 European leaders meet in Minsk and agree on a ceasefire in eastern Ukraine beginning on February 14. From left to right: Belarus President Alexander Lukashenko, Russian President Vladimir Putin, German Chancellor Angela Merkel, France's President Francois Hollande and Ukrainian President Petro Poroshenko.
MAXIM MALINOVSKY | AFP | Getty Images
Ukraine crisis: A timeline of the conflict 13 February 2015 Pro-Russian rebels in the city of Gorlivka, in the Donetsk region, fire missiles at Ukrainian forces in Debaltseve. Fighting continued in Debaltseve for a number of days after the Minsk ceasefire began.
ANDREY BORODULIN | AFP | Getty Images
Ukraine crisis: A timeline of the conflict 18 February 2015 Ukrainian soldiers repair the bullet-shattered windshield of their truck as their withdraw from the strategic town of Debaltseve. Following intense shelling from pro-Russian rebels, Ukrainian forces began to leave the town in the early hours of February 18.
Brendan Hoffman | Getty Images
Since the current ceasefire was announced, the UN estimates more than 300 people have been killed. That compares to more than 3,660 deaths over the course of the six-month conflict.
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