Frederic Kanoute scored his 16th goal of the season in Sevilla's 4-2 win against Levante in the Spanish league on Sunday.
Alexander Kerzhakov and Alejandro Alfaro also scored, while an own-goal by Levante midfielder Damiano Tommasi helped to end the UEFA Cup champions' three-game winless streak.
Sevilla has 41 points. FC Barcelona, which plays Celta Vigo later Sunday, has 39. Real Madrid has 38.
Kanoute, the league's leading scorer, netted in the 35th minute when he side-footed in a low cross by Kerzhakov on counterattack at the Ciutat de Valencia stadium.
Kerzhakov, a recent signing from Zenit St. Petersburg, notched his first Spanish league goal in the 55th, converting a pass from the right by Alfaro.
Tommasi scored an own goal in the 66th to give Sevilla a three-goal lead, although defender Frederic Dehu reduced the deficit with a header two minutes later.
Levante substitute Gustavo Reggi headed home in the 71st, but Alfaro scored Sevilla's fourth in the 76th.
Other 20th-round results Sunday were: Zaragoza 1, Deportivo La Coruna 1; Getafe 2, Osasuna 0; Mallorca 2, Recreativo Huelva 1; Real Sociedad 0, Athletic Bilbao 2; and Gimnastic Tarragona 4, Espanyol 0.
Also later Sunday, Valencia visits Real Betis.
Zaragoza stretched its winless run to three games against Deportivo, which remained without an away win this season.
Deportivo forward Sebastian Taborda scored with a 21st-minute header, but Diego Milito leveled for Zaragoza with an 80th-minute penalty for his 13th goal of the season. Taborda was ejected for the foul which led to the spot kick.
Getafe striker Daniel "Guiza" Gonzalez scored two first-half goals to defeat Osasuna in a rehearsal for the teams' Copa del Rey quarterfinal first leg on Wednesday.
Osasuna, which had four players ejected last week against Atletico Madrid, was reduced to 10 men when defender Josetxo Romero was sent off in the 78th.
Mallorca central defenders Sergio Ballesteros and Jose Carlos Nunes each scored before halftime to inflict Recreativo's first defeat in five games.
Recreativo midfielder Juanma Gomez reduced the deficit in the 49th, with Ballesteros receiving his second yellow card 20 minutes later.
Bilbao got the better of Sociedad with both teams in the Basque derby struggling against relegation.
Midfielder Andoni Iraola scored in the 13th and 69th minutes, while Sociedad midfielder Xabi Prieto missed a 36th-minute penalty.
Last-place Gimnastic, which has only won twice this season, underwent a transformation against Espanyol and led by four goals by halftime.
Javier Portillo put Gimnastic 1-0 up, before a penalty from Alejandro Campano and other goals from Antonio Pinilla and Cesar Navas.
Baros scores for Lyon as French champion's winless run extends to four
Milan Baros scored on full debut for Lyon in a 1-1 draw against Nice in the French league on Saturday, increasing its winless run to four matches.
The five-time defending champion had lost its previous two matches. Bakari Kone gave the visitors the lead in the 30th minute, but Baros leveled in the 39th after collecting a fine pass from Sidney Govou.
Lyon still leads by 13 points over second-place Lille, which won 1-0 at Bordeaux after an own-goal by Bordeaux striker Marouane Chamakh.
After 22 rounds, Lyon has 51 points, Lille 38 and Marseille has 36 after losing 2-0 at Le Mans.
In other matches, it was: Sedan 0, Monaco 1; Bordeaux 0, Lille 1; Nantes 0, Lorient 2; Toulouse 1, Troyes 1; Paris Saint-Germain 0, Sochaux 0; and Rennes 1, Valenciennes 0.
At Sedan, Baros' Czech Republic teammate, Jan Koller, scored Monaco's winner in the first minute.
Rennes won on Romain Danze's seventh-minute goal while Lorient's Pierre-Andre Gignac scored a neat volley and Fabrice Abriel added the other.
At Toulouse, Dominique Arribage scored for the home side before Cedric Barbosa equalized.
At Le Mans, James Fanchone and Grafite scored for the hosts.
Fanchone scored in the 38th minute through the legs of teammate Grafite and past unsighted Marseille goalkeeper Cedric Carasso after Marseille had failed to clear a corner.
Grafite sealed the win with a penalty kick in the 83rd. Marseille coach Albert Emon was sent to the stands soon after for heatedly arguing with the fourth official.
Canadian millionaire Jack Kachkar, who is expected to become Marseille's new owner by the end of February after current proprietor Robert Louis-Dreyfus accepted his offer, watched from the stands.
"This is a very exciting time for me," Kachkar said Saturday. "I'm a big Marseille fan."
Marseille dominated the first half, but failed to take numerous chances. Mamadou Niang went close in the 21st when he hit the post after running onto a pass from Franck Ribery.
On Sunday, Auxerre hosts Nancy and Saint-Etienne play at Lens.Reuse content