Manchester United duo Danny Welbeck and Phil Jones have been omitted from Stuart Pearce's England Under-21 squad for the forthcoming European Championship qualification double-header against Iceland and Belgium.
The Red Devils pair have broken into Fabio Capello's senior squad this season and have been left out of the 25-man group for the matches on Thursday, November 10 in Colchester and Monday, November 14 in Mons, Belgium.
Pearce, whose side have made a 100% start to the Group Eight campaign, will also be without injured West Ham midfielder Henri Lansbury.
He has called up five new faces in Crystal Palace's Nathaniel Clyne, Brighton's Lewis Dunk, Barnsley's Jacob Butterfield, Tottenham's Tom Carroll and Middlesbrough's Alex Nimely.
Middlesbrough goalkeeper Jason Steele is included following an injury.
Pearce, whose side followed an opening home win against Azerbaijan with victories away to Iceland and Norway, said: "We would have taken four points from those before the game so to come back with six out of six is a fantastic achievement, especially when you consider the adversity that led into the Norway game with three players picking up injuries.
"But there were no excuses and it really galvanised the group.
"Their attitude is fantastic and in this clutch of players we have some very solid individuals who have a great approach and a great attitude. I was impressed with them all.
"We're fortunate that we got two tricky away games out of the way, but we have to maximise that at home and make sure there are no slip-ups.
"With only one team certain of a place in the play-offs, dropping any points in the group puts you under real pressure."
England Under-21 squad to face Iceland and Belgium on November 10 and 14:
Amos (Manchester United), Butland (Birmingham), Steele (Middlesbrough), Baker (Aston Villa), Bennett (Peterborough), Briggs (Fulham), Clyne (Crystal Palace), Dawson (West Brom), Dunk (Brighton), Flanagan (Liverpool), Kelly (Liverpool), Smith (Tottenham) Barkley (Everton), Butterfield (Barnsley), Carroll (Tottenham), Gardner (Aston Villa), Henderson (Liverpool), Lowe (Blackburn), McEachran (Chelsea), Oxlade-Chamberlain (Arsenal), Rodwell (Everton), Delfouneso (Aston Villa), Nimely (Manchester City), Sordell (Watford), Wickham (Sunderland).
Bennett (Middlesbrough), Rudd (Norwich), Shelvey (Liverpool), Townsend (Tottenham), Gosling (Newcastle).