Joe Hart and Raheem Sterling will not take part in England’s forthcoming international friendlies against Germany and the Netherlands.
Burnley goalkeeper Tom Heaton has been called up to replace Hart, who sustained a calf problem while stretching to clear an under-hit backpass by Martin Demichelis.
Sterling suffered a groin problem in the game’s opening stages but, despite the winger’s withdrawal, manager Roy Hodgson will not add his selection of outfield players.
"Obviously it’s very disappointing for Joe and Raheem to suffer injuries which will rule them out of our games against Germany and Holland,” Hodgson said.
“They are important players in our squad and I wish them a speedy recovery.”
Heaton, who is yet to make his senior international debut, has represented every England age group from the under-16s upwards.
The 29-year-old was most recently included in the squad for last year’s Republic of Ireland and Slovenia games.
"Tom has been with us on several occasions and I am welcoming him back into the fold," said Hodgson.