Sunderland manager Gus Poyet has dropped both Wes Brown and Vito Mannone after their errors cost the sides two goals in the defeat to Arsenal last week.
Poyet, who brings in former Manchester City keeper Costel Pantilimon for Mannone, makes three other changes to the team that lost to Arsenal, with five players switched in total.
Anthony Reveillere is set to make his full debut at right-back, Santiago Vergini moves into the middle, Connor Wickham in for Adam Johnson and Jordi Gomez replacing Jack Rodwell.
Sunderland are searching for just their second Premier League win of the season.
For Crystal Palace, Neil Warnock makes just one change to the team that controversially drew with West Bromwich last week, with Scott Dann returning at centre-back to take the place of Adrian Marriappa.
That means that Julian Speroni, who was forced off last week after being elbowed by Craig Dawson, returns to start in goal for the Eagles.
Crystal Palace: Speroni, Kelly, Hangeland, Dann, Ward, Jedinak, Ledley, Zaha, Bolasie, Chamakh, Campbell.
Subs: Hennessey, Mariappa, Bannan, McArthur, Puncheon, Doyle, Gayle.
Sunderland: Pantilimon, Reveillere, Van Aanholt, O'Shea, Vergini, Cattermole, Larsson, Gomez, Buckley, Wickham, Fletcher.
Subs: Brown, Johnson, Altidore, Mavrias, Graham, Mannone.Reuse content