The former Barcelona and Bayern Munich head coach has endured a tough start to life in the Premier League but his side can close the gap on City to just one point with victory today.
The Red Devils start with Robin van Persie and Wayne Rooney up front, supported by Angel di Maria and Adnan Januzaj, while Manuel Pellegrini has given Stevan Jovetic a spot in his side.
The champions also make room for James Milner in midfield while Martin Demichelis is preferred to Eliaquim Mangala in central defence.
Manchester City: Hart, Zabaleta, Kolarov, Demichelis, Kompany, Fernando, Yaya Toure, Navas, Milner, Jovetic, Aguero.
Subs: Caballero, Clichy, Sagna, Fernandinho, Boyata, Dzeko, Nasri.
Manchester United: De Gea, Valencia, Smalling, Rojo, Shaw, Blind, Fellaini, Januzaj, Rooney, Di Maria, van Persie.
Subs: Lindegaard, McNair, Carrick, Fletcher, Herrera, Mata, Wilson.Reuse content