NFL round-up: Washington Redskins lose Robert Griffin III to dislocated ankle in rout of Jacksonville Jaguars; Seattle Seahawks suffer loss

Superbowl champions suffer defeat at the San Diego Chargers, Chicago Browns overcome the San Fransisco 49ers and Green Bay Packers come from behind to beat New York Jets

Robert Griffin III is carted off the field after suffering a dislocated ankle (Getty Images)

Robert Griffin III dislocated his left ankle and DeSean Jackson sprained his left shoulder in the first quarter, before Kirk Cousins stepped to complete 22 of 33 passes for 250 yards and a pair of touchdowns Sunday in the Washington Redskins' 41-10 romp past Jacksonville Jaguars.

Griffin was carted to the locker room with his leg in a splint and could be out for two months. He will undergo X-rays to determine if the ankle is broken.

Cousins subbed for Griffin and completed his first 12 passes. Ryan Kerrigan had four of the Redskins' 10 sacks, and Washington's defense didn't allow Jacksonville (0-2) past midfield until the final two minutes of the first half.

At San Diego, Antonio Gates had three touchdown catches as the Chargers controlled the tempo to keep Seattle's offense off the field in a 30-21 win over the Seahawks.

Gates' 21-yard catch late in the third quarter was epic, as the star tight end split two defenders and extended for Philip Rivers' pass, reaching out with his left hand to gather it in. Flat on his back, he held up the ball to show the officials he made the catch that gave San Diego a 27-14 lead.

Back-up quarter-back Kirk Cousins came in to lead the Redskins to a 41-10 win (Getty Images)

Chicago's Jay Cutler passed for three fourth-quarter touchdowns as the Bears downed the San Francisco 49ers 29-20.

The Cleveland Browns edged the New Orleans Saints 26-24 after Billy Cundiff kicked a 29-yard field goal with 3 seconds left. The win ended the Browns' nine-game losing streak in home openers and gave rookie coach Mike Pettine his first NFL win.

Tight end Antonio Gates reaches out to grasp a one-handed touchdown (Getty Images)

Aaron Rodgers threw for three touchdowns and Jordy Nelson had a career-high 209 yards receiving as the Green Bay Packers rallied from an 18-point deficit to beat the New York Jets 31-24.

New York appeared to tie it with 5 minutes left on a 37-yard catch by Jeremy Kerley on fourth down — but it was negated because the Jets (1-1) called a timeout from the sideline just before the snap. The Packers (1-1) held on from there to avoid their first 0-2 start since 2006.

Green Bay Packers receiver Jordy Nelson registered career high figures in the win over the New York Jets (Getty Images)

In other games, Terrance Knighton batted away Alex Smith's fourth-and-goal pass to Dwayne Bowe with 15 seconds left as the Denver Broncos defeated the Kansas City Chiefs 24-17, the Carolina Panthers downed the Detroit Lions 24-7, the Dallas Cowboys beat the Tennessee Titans 26-10 and the Houston Texans downed the Oakland Raiders 30-14.

The Cincinnati Bengals ran past the Atlanta Falcons 24-10, the Buffalos downed the Miami Dolphins 29-10, the St. Louis Rams edged the Tampa Bay Buccaneers 19-17 and the Arizona Cardinals were 25-14 winners over the New York Giants.

National Football League results:

Buffalo Bills 29 Miami Dolphins 10

Carolina Panthers 24 Detroit Lions 7

Cincinnati Bengals 24 Atlanta Falcons 10

Cleveland Browns 26 New Orleans Saints 24

Denver Broncos 24 Kansas City Chiefs 17

Green Bay Packers 31 New York Jets 24

Minnesota Vikings 7 New England Patriots 30

New York Giants 14 Arizona Cardinals 25

Oakland Raiders 14 Houston Texans 30

San Diego Chargers 30 Seattle Seahawks 21

Tampa Bay Buccaneers 17 St Louis Rams 19

Tennessee Titans 10 Dallas Cowboys 26

Washington Redskins 41 Jacksonville Jaguars 10