Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

Porn producers are threatening to quit filming in Los Angeles after voters approved a measure requiring adult-movie actors to wear condoms

Porn producers threaten to flee LA after condom law passes

Porn producers are threatening to quit filming in Los Angeles after voters approved a measure requiring adult-movie actors to wear condoms during shoots to protect them from sexually transmitted diseases.

Tackling disease is key to solving global poverty

Ahead of tomorrow’s High Level Panel meeting in London, a reflection on the critical role of health in and beyond the Millennium Development Goals.

Dara O'Briain: The law is gagging scientists

Defending a libel case is complex, time-consuming and extremely expensive. At the last general election, all three parties promised large-scale reform of the law – the first since 1843 – to protect public debate and freedom of expression. The Government published a Defamation Bill earlier this year, yet, nothing has changed.

Last night's viewing - Freddie Mercury: the Great Pretender – an Imagine Special, BBC1; Order and Disorder with Jim Al-Khalili BBC4

There is no disputing Freddie Mercury's greatness, or the charisma of his performances and how far the on-stage flamboyances diverged from the shy, RP-accented man he was out of the fan-filled stadiums. What is at contention here is whether we needed another Freddie Mercury documentary, so soon after BBC2's Queen documentary last year.

A country defined by equality, not ethnicity; and a plan to defeat HIV/Aids: my vision for Kenya

In an exclusive column for Independent Voices, Africa's first openly gay black politician explains why he is running for a seat in his country's Senate

Yoko Ono awards peace prize to Lady Gaga

Pop star Lady Gaga was awarded a peace prize by Yoko Ono in a ceremony in Iceland on Tuesday.

Scattered Sand: The story of China's rural migrants By Hsiao-Hung Pai

The painstaking journalism here offers remarkable insights into the plight of China's new citizens

Carol Jennings: 'Gradually it [Alzheimer's disease] was going through the family. It seemed like each year another one would have developed it'

Dementia: I have a 50:50 chance. But I try not to worry

Peter Popham meets the remarkable family from Nottingham who changed the way scientists thought about Alzheimer’s - and offered hope to millions

Impact of HIV/Aids: the late Fela Kuti

Our Kind of People, By Uzodinma Iweala

From the myth of promiscuity to unmentionable illness

Dotty vision: Yayoi Kusama

Polka dots are Japanese avant-garde artist Yayoi Kusama's lifelong inspiration, obsession and passion.

Rebecca Tyrell: 'If Kim Kardashian wants to match Liz Taylor, she’ll need to divorce Kanye next year'

Who knew that at the end, after that film-star life, after all the Oscars, the drama, the husbands and the jewellery, Elizabeth Taylor's final public communication, a month before she died, was a tweet to Kim Kardashian?

Women living with HIV receive support from a clinic in Kampala that is backed by international donations

Sir Elton John: The stigma of HIV almost killed me, it's still killing millions

Here's a story of a young man coming to terms with his sexuality, who got mixed up in drugs and drink. He took chances with unprotected sex, and he was at very high risk of contracting HIV. He hit rock bottom, his life was a mess.

Aids conference descends on US capital, but Obama stays away

As caravans of activists, scientists, celebrities and medical academics descended on Washington DC last night for the first International AIDS Conference to be held in the United States for twenty two years, there was dismay among some that the man who might have been the biggest turn, Barack Obama, was not planning to attend.

Françoise Barré-Sinoussi says a cure for HIV is possible

HIV cure research 'must not jeopardise existing projects'

The adoption of a new scientific Aids strategy to cure HIV rather than simply treat it with drugs for many years should not divert funding away from existing anti-Aids projects, a Nobel prize-winning scientist said yesterday.

Apply your conscience creatively

Masters courses with a strong social aspect are growing in popularity

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Russia Today’s new UK channel began broadcasting yesterday. Discussions so far have included why Britons see Russia as ‘the bad guy’
tv

New UK station Russia Today gives a very bizarre view of Britain

Voices
Left: An illustration of the original Jim Crowe, played by TD Rice Right: A Couple dressed as Ray and Janay Rice
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By performing as African Americans or Indians, white people get to play act a kind of 'imaginary liberation', writes Michael Mark Cohen

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John Moore inspired this Coca Cola Christmas advert
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people

Top Gear presenter is no stranger to foot-in-mouth controversy

Arts and Entertainment
Imelda Staunton as Dolores Umbridge in the Harry Potter films
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New essay by JK Rowling went live on Pottermore site this morning

Sport
A Rutherford Raiders shirt with the PornHub sponsorship
football

Arts and Entertainment
Charlie Sheen said he would
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Daniel Radcliffe gives a strong performance in Horns
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Apple CEO Timothy Cook
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The drugs revolution starts now as MPs agree its high time for change

The drugs revolution starts now as MPs agree its high time for change

Commons debate highlights growing cross-party consensus on softening UK drugs legislation, unchanged for 43 years
The camera is turned on tabloid editors in Richard Peppiatt's 'One Rogue Reporter'

Gotcha! The camera is turned on tabloid editors

Hugh Grant says Richard Peppiatt's 'One Rogue Reporter' documentary will highlight issues raised by Leveson
Fall of the Berlin Wall: It was thanks to Mikhail Gorbachev that this symbol of division fell

Fall of the Berlin Wall

It was thanks to Gorbachev that this symbol of division fell
Halloween 2014: What makes Ouija boards, demon dolls, and evil clowns so frightening?

What makes ouija boards and demon dolls scary?

Ouija boards, demon dolls, evil children and clowns are all classic tropes of horror, and this year’s Halloween releases feature them all. What makes them so frightening, decade after decade?
A safari in modern Britain: Rose Rouse reveals how her four-year tour of Harlesden taught her as much about the UK as it did about NW10

Rose Rouse's safari in modern Britain

Rouse decided to walk and talk with as many different people as possible in her neighbourhood of Harlesden and her experiences have been published in a new book
Welcome to my world of no smell and odd tastes: How a bike accident left one woman living with unwanted food mash-ups

'My world of no smell and odd tastes'

A head injury from a bicycle accident had the surprising effect of robbing Nell Frizzell of two of her senses

Matt Parker is proud of his square roots

The "stand-up mathematician" is using comedy nights to preach maths to big audiences
Paul Scholes column: Beating Manchester City is vital part of life at Manchester United. This is first major test for Luke Shaw, Angel Di Maria and Radamel Falcao – it’s not a game to lose

Paul Scholes column

Beating City is vital part of life at United. This is first major test for Shaw, Di Maria and Falcao – it’s not a game to lose
Frank Warren: Call me an old git, but I just can't see that there's a place for women’s boxing

Frank Warren column

Call me an old git, but I just can't see that there's a place for women’s boxing
Adrian Heath interview: Former Everton striker prepares his Orlando City side for the MLS - and having Kaka in the dressing room

Adrian Heath's American dream...

Former Everton striker prepares his Orlando City side for the MLS - and having Kaka in the dressing room
Simon Hart: Manchester City will rise again but they need to change their attitude

Manchester City will rise again but they need to change their attitude

Manuel Pellegrini’s side are too good to fail and derby allows them to start again, says Simon Hart
Isis in Syria: A general reveals the lack of communication with the US - and his country's awkward relationship with their allies-by-default

A Syrian general speaks

A senior officer of Bashar al-Assad’s regime talks to Robert Fisk about his army’s brutal struggle with Isis, in a dirty war whose challenges include widespread atrocities
‘A bit of a shock...’ Cambridge economist with Glasgow roots becomes Zambia’s acting President

‘A bit of a shock...’ Economist with Glasgow roots becomes Zambia’s acting President

Guy Scott's predecessor, Michael Sata, died in a London hospital this week after a lengthy illness
Fall of the Berlin Wall: History catches up with Erich Honecker - the East German leader who praised the Iron Curtain and claimed it prevented a Third World War

Fall of the Berlin Wall

History catches up with Erich Honecker - the East German leader who praised the Iron Curtain and claimed it prevented a Third World War
How to turn your mobile phone into easy money

Turn your mobile phone into easy money

There are 90 million unused mobiles in the UK, which would be worth £7bn if we cashed them in, says David Crookes