Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

Porn producers are threatening to quit filming in Los Angeles after voters approved a measure requiring adult-movie actors to wear condoms

Porn producers threaten to flee LA after condom law passes

Porn producers are threatening to quit filming in Los Angeles after voters approved a measure requiring adult-movie actors to wear condoms during shoots to protect them from sexually transmitted diseases.

Tackling disease is key to solving global poverty

Ahead of tomorrow’s High Level Panel meeting in London, a reflection on the critical role of health in and beyond the Millennium Development Goals.

Dara O'Briain: The law is gagging scientists

Defending a libel case is complex, time-consuming and extremely expensive. At the last general election, all three parties promised large-scale reform of the law – the first since 1843 – to protect public debate and freedom of expression. The Government published a Defamation Bill earlier this year, yet, nothing has changed.

Last night's viewing - Freddie Mercury: the Great Pretender – an Imagine Special, BBC1; Order and Disorder with Jim Al-Khalili BBC4

There is no disputing Freddie Mercury's greatness, or the charisma of his performances and how far the on-stage flamboyances diverged from the shy, RP-accented man he was out of the fan-filled stadiums. What is at contention here is whether we needed another Freddie Mercury documentary, so soon after BBC2's Queen documentary last year.

A country defined by equality, not ethnicity; and a plan to defeat HIV/Aids: my vision for Kenya

In an exclusive column for Independent Voices, Africa's first openly gay black politician explains why he is running for a seat in his country's Senate

Yoko Ono awards peace prize to Lady Gaga

Pop star Lady Gaga was awarded a peace prize by Yoko Ono in a ceremony in Iceland on Tuesday.

Scattered Sand: The story of China's rural migrants By Hsiao-Hung Pai

The painstaking journalism here offers remarkable insights into the plight of China's new citizens

Carol Jennings: 'Gradually it [Alzheimer's disease] was going through the family. It seemed like each year another one would have developed it'

Dementia: I have a 50:50 chance. But I try not to worry

Peter Popham meets the remarkable family from Nottingham who changed the way scientists thought about Alzheimer’s - and offered hope to millions

Impact of HIV/Aids: the late Fela Kuti

Our Kind of People, By Uzodinma Iweala

From the myth of promiscuity to unmentionable illness

Dotty vision: Yayoi Kusama

Polka dots are Japanese avant-garde artist Yayoi Kusama's lifelong inspiration, obsession and passion.

Rebecca Tyrell: 'If Kim Kardashian wants to match Liz Taylor, she’ll need to divorce Kanye next year'

Who knew that at the end, after that film-star life, after all the Oscars, the drama, the husbands and the jewellery, Elizabeth Taylor's final public communication, a month before she died, was a tweet to Kim Kardashian?

Women living with HIV receive support from a clinic in Kampala that is backed by international donations

Sir Elton John: The stigma of HIV almost killed me, it's still killing millions

Here's a story of a young man coming to terms with his sexuality, who got mixed up in drugs and drink. He took chances with unprotected sex, and he was at very high risk of contracting HIV. He hit rock bottom, his life was a mess.

Aids conference descends on US capital, but Obama stays away

As caravans of activists, scientists, celebrities and medical academics descended on Washington DC last night for the first International AIDS Conference to be held in the United States for twenty two years, there was dismay among some that the man who might have been the biggest turn, Barack Obama, was not planning to attend.

Françoise Barré-Sinoussi says a cure for HIV is possible

HIV cure research 'must not jeopardise existing projects'

The adoption of a new scientific Aids strategy to cure HIV rather than simply treat it with drugs for many years should not divert funding away from existing anti-Aids projects, a Nobel prize-winning scientist said yesterday.

Apply your conscience creatively

Masters courses with a strong social aspect are growing in popularity

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Day In a Page

Burgundy, the River Rhone & Provence – MS Swiss Corona - seven nights from £999pp
Lake Maggiore, Orta and the Matterhorn – seven nights from £899pp
Sicily – seven nights from £939pp
Pompeii, Capri and the Bay of Naples - seven nights from £799pp
Istanbul Ephesus & Troy – six nights from £859pp
Mary Rose – two nights from £319pp
Ukraine crisis: The phoney war is over as Russian troops and armour pour across the border

The phoney war is over

Russian troops and armour pour into Ukraine
Potatoes could be off the menu as crop pests threaten UK

Potatoes could be off the menu as crop pests threaten UK

The world’s entire food system is under attack - and Britain is most at risk, according to a new study
Gangnam smile: why the Chinese are flocking to South Korea to buy a new face

Gangnam smile: why the Chinese are flocking to South Korea to buy a new face

Seoul's plastic surgery industry is booming thanks to the popularity of the K-Pop look
From Mozart to Orson Welles: Creative geniuses who peaked too soon

Creative geniuses who peaked too soon

After the death of Sandy Wilson, 90, who wrote his only hit musical in his twenties, John Walsh wonders what it's like to peak too soon and go on to live a life more ordinary
Caught in the crossfire of a cyber Cold War

Caught in the crossfire of a cyber Cold War

Fears are mounting that Vladimir Putin has instructed hackers to target banks like JP Morgan
Salomé's feminine wiles have inspired writers, painters and musicians for 2,000 years

Salomé: A head for seduction

Salomé's feminine wiles have inspired writers, painters and musicians for 2,000 years. Now audiences can meet the Biblical femme fatale in two new stage and screen projects
From Bram Stoker to Stanley Kubrick, the British Library's latest exhibition celebrates all things Gothic

British Library celebrates all things Gothic

Forthcoming exhibition Terror and Wonder: The Gothic Imagination will be the UK's largest ever celebration of Gothic literature
The Hard Rock Café's owners are embroiled in a bitter legal dispute - but is the restaurant chain worth fighting for?

Is the Hard Rock Café worth fighting for?

The restaurant chain's owners are currently embroiled in a bitter legal dispute
Caribbean cuisine is becoming increasingly popular in the UK ... and there's more to it than jerk chicken at carnival

In search of Caribbean soul food

Caribbean cuisine is becoming increasingly popular in the UK ... and there's more to it than jerk chicken at carnival
11 best face powders

11 best face powders

Sweep away shiny skin with our pick of the best pressed and loose powder bases
England vs Norway: Roy Hodgson's hands tied by exploding top flight

Roy Hodgson's hands tied by exploding top flight

Lack of Englishmen at leading Premier League clubs leaves manager hamstrung
Angel Di Maria and Cristiano Ronaldo: A tale of two Manchester United No 7s

Di Maria and Ronaldo: A tale of two Manchester United No 7s

They both inherited the iconic shirt at Old Trafford, but the £59.7m new boy is joining a club in a very different state
Israel-Gaza conflict: No victory for Israel despite weeks of death and devastation

Robert Fisk: No victory for Israel despite weeks of devastation

Palestinians have won: they are still in Gaza, and Hamas is still there
Mary Beard writes character reference for Twitter troll who called her a 'slut'

Unlikely friends: Mary Beard and the troll who called her a ‘filthy old slut’

The Cambridge University classicist even wrote the student a character reference
America’s new apartheid: Prosperous white districts are choosing to break away from black cities and go it alone

America’s new apartheid

Prosperous white districts are choosing to break away from black cities and go it alone