Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

Porn producers are threatening to quit filming in Los Angeles after voters approved a measure requiring adult-movie actors to wear condoms

Porn producers threaten to flee LA after condom law passes

Porn producers are threatening to quit filming in Los Angeles after voters approved a measure requiring adult-movie actors to wear condoms during shoots to protect them from sexually transmitted diseases.

Tackling disease is key to solving global poverty

Ahead of tomorrow’s High Level Panel meeting in London, a reflection on the critical role of health in and beyond the Millennium Development Goals.

Dara O'Briain: The law is gagging scientists

Defending a libel case is complex, time-consuming and extremely expensive. At the last general election, all three parties promised large-scale reform of the law – the first since 1843 – to protect public debate and freedom of expression. The Government published a Defamation Bill earlier this year, yet, nothing has changed.

Last night's viewing - Freddie Mercury: the Great Pretender – an Imagine Special, BBC1; Order and Disorder with Jim Al-Khalili BBC4

There is no disputing Freddie Mercury's greatness, or the charisma of his performances and how far the on-stage flamboyances diverged from the shy, RP-accented man he was out of the fan-filled stadiums. What is at contention here is whether we needed another Freddie Mercury documentary, so soon after BBC2's Queen documentary last year.

A country defined by equality, not ethnicity; and a plan to defeat HIV/Aids: my vision for Kenya

In an exclusive column for Independent Voices, Africa's first openly gay black politician explains why he is running for a seat in his country's Senate

Yoko Ono awards peace prize to Lady Gaga

Pop star Lady Gaga was awarded a peace prize by Yoko Ono in a ceremony in Iceland on Tuesday.

Scattered Sand: The story of China's rural migrants By Hsiao-Hung Pai

The painstaking journalism here offers remarkable insights into the plight of China's new citizens

Carol Jennings: 'Gradually it [Alzheimer's disease] was going through the family. It seemed like each year another one would have developed it'

Dementia: I have a 50:50 chance. But I try not to worry

Peter Popham meets the remarkable family from Nottingham who changed the way scientists thought about Alzheimer’s - and offered hope to millions

Impact of HIV/Aids: the late Fela Kuti

Our Kind of People, By Uzodinma Iweala

From the myth of promiscuity to unmentionable illness

Dotty vision: Yayoi Kusama

Polka dots are Japanese avant-garde artist Yayoi Kusama's lifelong inspiration, obsession and passion.

Rebecca Tyrell: 'If Kim Kardashian wants to match Liz Taylor, she’ll need to divorce Kanye next year'

Who knew that at the end, after that film-star life, after all the Oscars, the drama, the husbands and the jewellery, Elizabeth Taylor's final public communication, a month before she died, was a tweet to Kim Kardashian?

Women living with HIV receive support from a clinic in Kampala that is backed by international donations

Sir Elton John: The stigma of HIV almost killed me, it's still killing millions

Here's a story of a young man coming to terms with his sexuality, who got mixed up in drugs and drink. He took chances with unprotected sex, and he was at very high risk of contracting HIV. He hit rock bottom, his life was a mess.

Aids conference descends on US capital, but Obama stays away

As caravans of activists, scientists, celebrities and medical academics descended on Washington DC last night for the first International AIDS Conference to be held in the United States for twenty two years, there was dismay among some that the man who might have been the biggest turn, Barack Obama, was not planning to attend.

Françoise Barré-Sinoussi says a cure for HIV is possible

HIV cure research 'must not jeopardise existing projects'

The adoption of a new scientific Aids strategy to cure HIV rather than simply treat it with drugs for many years should not divert funding away from existing anti-Aids projects, a Nobel prize-winning scientist said yesterday.

Apply your conscience creatively

Masters courses with a strong social aspect are growing in popularity

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Friends is celebrating its 20th anniversary this year
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Jack Cooksey goes for the grand unveiling - moments before dropping his new iPhone 6 on the floor
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Matthew Beard, Ben Schnetzer, Douglas Booth and Jack Farthing in ‘The Riot Club’
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Mystery of the Ground Zero wedding photo

A shot in the dark

Mystery of the wedding photo from Ground Zero
His life, the universe and everything

His life, the universe and everything

New biography sheds light on comic genius of Douglas Adams
Save us from small screen superheroes

Save us from small screen superheroes

Shows like Agents of S.H.I.E.L.D are little more than marketing tools
Reach for the skies

Reach for the skies

From pools to football pitches, rooftop living is looking up
These are the 12 best hotel spas in the UK

12 best hotel spas in the UK

Some hotels go all out on facilities; others stand out for the sheer quality of treatments
These Iranian-controlled Shia militias used to specialise in killing American soldiers. Now they are fighting Isis, backed up by US airstrikes

Widespread fear of Isis is producing strange bedfellows

Iranian-controlled Shia militias that used to kill American soldiers are now fighting Isis, helped by US airstrikes
Topshop goes part Athena poster, part last spring Prada

Topshop goes part Athena poster, part last spring Prada

Shoppers don't come to Topshop for the unique
How to make a Lego masterpiece

How to make a Lego masterpiece

Toy breaks out of the nursery and heads for the gallery
Meet the ‘Endies’ – city dwellers who are too poor to have fun

Meet the ‘Endies’ – city dwellers who are too poor to have fun

Urbanites are cursed with an acronym pointing to Employed but No Disposable Income or Savings
Paisley’s decision to make peace with IRA enemies might remind the Arabs of Sadat

Ian Paisley’s decision to make peace with his IRA enemies

His Save Ulster from Sodomy campaign would surely have been supported by many a Sunni imam
'She was a singer, a superstar, an addict, but to me, her mother, she is simply Amy'

'She was a singer, a superstar, an addict, but to me, her mother, she is simply Amy'

Exclusive extract from Janis Winehouse's poignant new memoir
Is this the role to win Cumberbatch an Oscar?

Is this the role to win Cumberbatch an Oscar?

The Imitation Game, film review
England and Roy Hodgson take a joint step towards redemption in Basel

England and Hodgson take a joint step towards redemption

Welbeck double puts England on the road to Euro 2016
Relatives fight over Vivian Maier’s rare photos

Relatives fight over Vivian Maier’s rare photos

Pictures removed from public view as courts decide ownership
‘Fashion has to be fun. It’s a big business, not a cure for cancer’

‘Fashion has to be fun. It’s a big business, not a cure for cancer’

Donatella Versace at New York Fashion Week