Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

Porn producers are threatening to quit filming in Los Angeles after voters approved a measure requiring adult-movie actors to wear condoms

Porn producers threaten to flee LA after condom law passes

Porn producers are threatening to quit filming in Los Angeles after voters approved a measure requiring adult-movie actors to wear condoms during shoots to protect them from sexually transmitted diseases.

Tackling disease is key to solving global poverty

Ahead of tomorrow’s High Level Panel meeting in London, a reflection on the critical role of health in and beyond the Millennium Development Goals.

Dara O'Briain: The law is gagging scientists

Defending a libel case is complex, time-consuming and extremely expensive. At the last general election, all three parties promised large-scale reform of the law – the first since 1843 – to protect public debate and freedom of expression. The Government published a Defamation Bill earlier this year, yet, nothing has changed.

Last night's viewing - Freddie Mercury: the Great Pretender – an Imagine Special, BBC1; Order and Disorder with Jim Al-Khalili BBC4

There is no disputing Freddie Mercury's greatness, or the charisma of his performances and how far the on-stage flamboyances diverged from the shy, RP-accented man he was out of the fan-filled stadiums. What is at contention here is whether we needed another Freddie Mercury documentary, so soon after BBC2's Queen documentary last year.

A country defined by equality, not ethnicity; and a plan to defeat HIV/Aids: my vision for Kenya

In an exclusive column for Independent Voices, Africa's first openly gay black politician explains why he is running for a seat in his country's Senate

Yoko Ono awards peace prize to Lady Gaga

Pop star Lady Gaga was awarded a peace prize by Yoko Ono in a ceremony in Iceland on Tuesday.

Scattered Sand: The story of China's rural migrants By Hsiao-Hung Pai

The painstaking journalism here offers remarkable insights into the plight of China's new citizens

Carol Jennings: 'Gradually it [Alzheimer's disease] was going through the family. It seemed like each year another one would have developed it'

Dementia: I have a 50:50 chance. But I try not to worry

Peter Popham meets the remarkable family from Nottingham who changed the way scientists thought about Alzheimer’s - and offered hope to millions

Impact of HIV/Aids: the late Fela Kuti

Our Kind of People, By Uzodinma Iweala

From the myth of promiscuity to unmentionable illness

Dotty vision: Yayoi Kusama

Polka dots are Japanese avant-garde artist Yayoi Kusama's lifelong inspiration, obsession and passion.

Rebecca Tyrell: 'If Kim Kardashian wants to match Liz Taylor, she’ll need to divorce Kanye next year'

Who knew that at the end, after that film-star life, after all the Oscars, the drama, the husbands and the jewellery, Elizabeth Taylor's final public communication, a month before she died, was a tweet to Kim Kardashian?

Women living with HIV receive support from a clinic in Kampala that is backed by international donations

Sir Elton John: The stigma of HIV almost killed me, it's still killing millions

Here's a story of a young man coming to terms with his sexuality, who got mixed up in drugs and drink. He took chances with unprotected sex, and he was at very high risk of contracting HIV. He hit rock bottom, his life was a mess.

Aids conference descends on US capital, but Obama stays away

As caravans of activists, scientists, celebrities and medical academics descended on Washington DC last night for the first International AIDS Conference to be held in the United States for twenty two years, there was dismay among some that the man who might have been the biggest turn, Barack Obama, was not planning to attend.

Françoise Barré-Sinoussi says a cure for HIV is possible

HIV cure research 'must not jeopardise existing projects'

The adoption of a new scientific Aids strategy to cure HIV rather than simply treat it with drugs for many years should not divert funding away from existing anti-Aids projects, a Nobel prize-winning scientist said yesterday.

Apply your conscience creatively

Masters courses with a strong social aspect are growing in popularity

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Independent Travel
Pompeii, Capri & the Bay of Naples
Dubrovnik, the Dalmatian Coast & Montenegro
Burgundy, the River Rhone & Provence
Lisbon, Oporto and the Douro Valley
Lake Garda, Venice & Verona
Spain
Prices correct as of 23 January 2015
Syria crisis: Celebrities call on David Cameron to take more refugees as one young mother tells of torture by Assad regime

Celebrities call on David Cameron to take more Syrian refugees

One young mother tells of torture by Assad regime
The enemy within: People who hear voices in their heads are being encouraged to talk back – with promising results

The enemy within

People who hear voices in their heads are being encouraged to talk back
'In Auschwitz you got used to anything'

'In Auschwitz you got used to anything'

Survivors of the Nazi concentration camp remember its horror, 70 years on
Autumn/winter menswear 2015: The uniforms that make up modern life come to the fore

Autumn/winter menswear 2015

The uniforms that make up modern life come to the fore
'I'm gay, and plan to fight military homophobia'

'I'm gay, and plan to fight military homophobia'

Army general planning to come out
Iraq invasion 2003: The bloody warnings six wise men gave to Tony Blair as he prepared to launch poorly planned campaign

What the six wise men told Tony Blair

Months before the invasion of Iraq in 2003, experts sought to warn the PM about his plans. Here, four of them recall that day
25 years of The Independent on Sunday: The stories, the writers and the changes over the last quarter of a century

25 years of The Independent on Sunday

The stories, the writers and the changes over the last quarter of a century
Homeless Veterans appeal: 'Really caring is a dangerous emotion in this kind of work'

Homeless Veterans appeal

As head of The Soldiers' Charity, Martin Rutledge has to temper compassion with realism. He tells Chris Green how his Army career prepared him
Wu-Tang Clan and The Sexual Objects offer fans a chance to own the only copies of their latest albums

Smash hit go under the hammer

It's nice to pick up a new record once in a while, but the purchasers of two latest releases can go a step further - by buying the only copy
Geeks who rocked the world: Documentary looks back at origins of the computer-games industry

The geeks who rocked the world

A new documentary looks back at origins of the computer-games industry
Belle & Sebastian interview: Stuart Murdoch reveals how the band is taking a new direction

Belle & Sebastian is taking a new direction

Twenty years ago, Belle & Sebastian was a fey indie band from Glasgow. It still is – except today, as prime mover Stuart Murdoch admits, it has a global cult following, from Hollywood to South Korea
America: Land of the free, home of the political dynasty

America: Land of the free, home of the political dynasty

These days in the US things are pretty much stuck where they are, both in politics and society at large, says Rupert Cornwell
A graphic history of US civil rights – in comic book form

A graphic history of US civil rights – in comic book form

A veteran of the Fifties campaigns is inspiring a new generation of activists
Winston Churchill: the enigma of a British hero

Winston Churchill: the enigma of a British hero

A C Benson called him 'a horrid little fellow', George Orwell would have shot him, but what a giant he seems now, says DJ Taylor
Growing mussels: Precious freshwater shellfish are thriving in a unique green project

Growing mussels

Precious freshwater shellfish are thriving in a unique green project