Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

Porn producers are threatening to quit filming in Los Angeles after voters approved a measure requiring adult-movie actors to wear condoms

Porn producers threaten to flee LA after condom law passes

Porn producers are threatening to quit filming in Los Angeles after voters approved a measure requiring adult-movie actors to wear condoms during shoots to protect them from sexually transmitted diseases.

Tackling disease is key to solving global poverty

Ahead of tomorrow’s High Level Panel meeting in London, a reflection on the critical role of health in and beyond the Millennium Development Goals.

Dara O'Briain: The law is gagging scientists

Defending a libel case is complex, time-consuming and extremely expensive. At the last general election, all three parties promised large-scale reform of the law – the first since 1843 – to protect public debate and freedom of expression. The Government published a Defamation Bill earlier this year, yet, nothing has changed.

Last night's viewing - Freddie Mercury: the Great Pretender – an Imagine Special, BBC1; Order and Disorder with Jim Al-Khalili BBC4

There is no disputing Freddie Mercury's greatness, or the charisma of his performances and how far the on-stage flamboyances diverged from the shy, RP-accented man he was out of the fan-filled stadiums. What is at contention here is whether we needed another Freddie Mercury documentary, so soon after BBC2's Queen documentary last year.

A country defined by equality, not ethnicity; and a plan to defeat HIV/Aids: my vision for Kenya

In an exclusive column for Independent Voices, Africa's first openly gay black politician explains why he is running for a seat in his country's Senate

Yoko Ono awards peace prize to Lady Gaga

Pop star Lady Gaga was awarded a peace prize by Yoko Ono in a ceremony in Iceland on Tuesday.

Scattered Sand: The story of China's rural migrants By Hsiao-Hung Pai

The painstaking journalism here offers remarkable insights into the plight of China's new citizens

Carol Jennings: 'Gradually it [Alzheimer's disease] was going through the family. It seemed like each year another one would have developed it'

Dementia: I have a 50:50 chance. But I try not to worry

Peter Popham meets the remarkable family from Nottingham who changed the way scientists thought about Alzheimer’s - and offered hope to millions

Impact of HIV/Aids: the late Fela Kuti

Our Kind of People, By Uzodinma Iweala

From the myth of promiscuity to unmentionable illness

Dotty vision: Yayoi Kusama

Polka dots are Japanese avant-garde artist Yayoi Kusama's lifelong inspiration, obsession and passion.

Rebecca Tyrell: 'If Kim Kardashian wants to match Liz Taylor, she’ll need to divorce Kanye next year'

Who knew that at the end, after that film-star life, after all the Oscars, the drama, the husbands and the jewellery, Elizabeth Taylor's final public communication, a month before she died, was a tweet to Kim Kardashian?

Women living with HIV receive support from a clinic in Kampala that is backed by international donations

Sir Elton John: The stigma of HIV almost killed me, it's still killing millions

Here's a story of a young man coming to terms with his sexuality, who got mixed up in drugs and drink. He took chances with unprotected sex, and he was at very high risk of contracting HIV. He hit rock bottom, his life was a mess.

Aids conference descends on US capital, but Obama stays away

As caravans of activists, scientists, celebrities and medical academics descended on Washington DC last night for the first International AIDS Conference to be held in the United States for twenty two years, there was dismay among some that the man who might have been the biggest turn, Barack Obama, was not planning to attend.

Françoise Barré-Sinoussi says a cure for HIV is possible

HIV cure research 'must not jeopardise existing projects'

The adoption of a new scientific Aids strategy to cure HIV rather than simply treat it with drugs for many years should not divert funding away from existing anti-Aids projects, a Nobel prize-winning scientist said yesterday.

Apply your conscience creatively

Masters courses with a strong social aspect are growing in popularity

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Blundering Tony Blair quits as Middle East peace envoy – only Israel will miss him

Blundering Blair quits as Middle East peace envoy – only Israel will miss him

For Arabs – and for Britons who lost their loved ones in his shambolic war in Iraq – his appointment was an insult, says Robert Fisk
Fifa corruption arrests: All hail the Feds for riding to football's rescue

Fifa corruption arrests

All hail the Feds for riding to football's rescue, says Ian Herbert
Isis in Syria: The Kurdish enclave still resisting the tyranny of President Assad and militant fighters

The Kurdish enclave still resisting the tyranny of Assad and Isis

In Syrian Kurdish cantons along the Turkish border, the progressive aims of the 2011 uprising are being enacted despite the war. Patrick Cockburn returns to Amuda
How I survived Cambodia's Killing Fields: Acclaimed surgeon SreyRam Kuy celebrates her mother's determination to escape the US

How I survived Cambodia's Killing Fields

Acclaimed surgeon SreyRam Kuy celebrates her mother's determination to escape to the US
Stephen Mangan interview: From posh buffoon to pregnant dad, the actor has quite a range

How Stephen Mangan got his range

Posh buffoon, hapless writer, pregnant dad - Mangan is certainly a versatile actor
The ZX Spectrum has been crowd-funded back into play - with some 21st-century tweaks

The ZX Spectrum is back

The ZX Spectrum was the original - and for some players, still the best. David Crookes meets the fans who've kept the games' flames lit
Grace of Monaco film panned: even the screenwriter pours scorn on biopic starring Nicole Kidman

Even the screenwriter pours scorn on Grace of Monaco biopic

The critics had a field day after last year's premiere, but the savaging goes on
Menstrual Hygiene Day: The strange ideas people used to believe about periods

Menstrual Hygiene Day: The strange ideas people once had about periods

If one was missed, vomiting blood was seen as a viable alternative
The best work perks: From free travel cards to making dreams come true (really)

The quirks of work perks

From free travel cards to making dreams come true (really)
Is bridge the latest twee pastime to get hip?

Is bridge becoming hip?

The number of young players has trebled in the past year. Gillian Orr discovers if this old game has new tricks
Long author-lists on research papers are threatening the academic work system

The rise of 'hyperauthorship'

Now that academic papers are written by thousands (yes, thousands) of contributors, it's getting hard to tell workers from shirkers
The rise of Lego Clubs: How toys are helping children struggling with social interaction to build better relationships

The rise of Lego Clubs

How toys are helping children struggling with social interaction to build better relationships
5 best running glasses

On your marks: 5 best running glasses

Whether you’re pounding pavements, parks or hill passes, keep your eyes protected in all weathers
Joe Root: 'Ben Stokes gives everything – he’s rubbing off on us all'

'Ben Stokes gives everything – he’s rubbing off on us all'

Joe Root says the England dressing room is a happy place again – and Stokes is the catalyst
Raif Badawi: Wife pleads for fresh EU help as Saudi blogger's health worsens

Please save my husband

As the health of blogger Raif Badawi worsens in prison, his wife urges EU governments to put pressure on the Saudi Arabian royal family to allow her husband to join his family in Canada