Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

William Roache, child abuse and past lives

Judging by his comments, I guess my disability is just a punishment for being a total badass in a previous life?

Saul Sanchez, 48: “He is a very simple man. You know it because he liked to come here and just be with us. He is just a normal person who would eat and drink with us”

'The Slum Pope? He is bigger than that – he is for all the poor people'

Before becoming Pope, Jorge Mario Bergoglio won the hearts of the slum people ministering to the poor and sick

Signs of a rethink on America's War on Drugs

Maryland looks likely to follow Washington and decriminalise marijuana

HIV drugs could 'functionally cure' about 10% of early diagnosed patients

Breakthrough follows reports of a baby girl in the US who was 'cured' after very early treatment

Editorial: A baby step forward in the fight against Aids

HIV/Aids has proved a stubborn problem. Thirty years on from the discovery of the virus – after tens of millions of deaths – there is still only one recorded case of an adult sufferer being cured. (The so-called "Berlin patient" had his entire immune system replaced with that from someone resistant to the disease.)

'Cured' baby remains solitary reminder that genuine solution to HIV is still a long way off

This year marks the 30th anniversary of the discovery of the human immunodeficiency virus (HIV), so it is with great excitement that the Aids community has received the news that a baby has been “cured” of the virus.

Doctor C Everett Koop: Surgeon General who angered US conservatives with his stance on abortion and Aids

Doctor C Everett Koop: Surgeon General who angered US conservatives with his stance on abortion and Aids

Dr C Everett Koop, who died on 25 February at the age of 96, was a leading US health official throughout much of the 1980s who spoke frankly about Aids and railed against smoking. An evangelical Christian, Koop shocked his conservative supporters when he endorsed condoms and sex education to stop the spread of Aids. He was surgeon general for seven years during the Ronald Reagan and George HW Bush administrations. He carried out a crusade to end smoking in the US.

Poverty and poor sanitation are key factors in the spread of the disease

Bill Gates: We cannot stand still on polio, but we can push ahead and end it

Through its judicious use of foreign aid, the UK has helped drive this recent progress

Man charged with murder of gay mayoral candidate

A man has been charged with the murder of an openly gay candidate for mayor of a Mississippi town.

Elton John finds second baby 'much easier' than first

David Furnish has told how he and partner Sir Elton John have found parenthood much easier the second time around.

A couple kisses in Times Square, New York

'Severe epidemic' of sexually transmitted diseases sweeping the US, warn health experts in Valentine’s Day announcement

Centers for Disease Control and Prevention says 20 million new STD cases are diagnosed every year

The ‘Love Is In My Blood’ campaign involves Twitter messages and a video in Piccadilly Circus

Elton John and Ai Weiwei join forces to launch Valentine's Day Aids campaign

Sir Elton John and the Chinese artist Ai Weiwei will today join forces to support a Valentine's Day campaign to raise awareness of Aids.

It was not widely known Mike Freer, a Tory MP, was gay

Mike Freer: A gay Tory MP on why he went public

Mike Freer hesitated for a long time over whether to say anything at all when his fellow MPs argued over whether to legalise gay marriage. He is one of the newer MPs and it was not widely known in Parliament that he is gay.

'Unsafe sexual behaviour' leaves HIV levels among gay men unchanged, says report

“Unsafe sexual behaviour” and a lack of testing is being blamed for a failure to cut the number of cases of HIV among gay and bisexual men in the last decade.

Pop star Madonna cuts the ribbon at the ground breaking ceremony for the Raising Malawi Academy for Girls in Malawi in 2009

Madonna's charitable endeavours rubbished by Malawi education authorities

Madonna’s charitable endeavours were dealt another blow when Malawi’s Education Minister flatly denied the pop star’s claims that her charity had built 10 new schools in the country.

Career Services

Day In a Page

Burgundy, the River Rhone & Provence – MS Swiss Corona - seven nights from £999pp
Lake Maggiore, Orta and the Matterhorn – seven nights from £899pp
Sicily – seven nights from £939pp
Pompeii, Capri and the Bay of Naples - seven nights from £799pp
Istanbul Ephesus & Troy – six nights from £859pp
Mary Rose – two nights from £319pp
Middle East crisis: We know all too much about the cruelty of Isis – but all too little about who they are

We know all too much about the cruelty of Isis – but all too little about who they are

Now Obama has seen the next US reporter to be threatened with beheading, will he blink, asks Robert Fisk
Neanderthals lived alongside humans for centuries, latest study shows

Final resting place of our Neanderthal neighbours revealed

Bones dated to 40,000 years ago show species may have died out in Belgium species co-existed
Scottish independence: The new Scots who hold fate of the UK in their hands

The new Scots who hold fate of the UK in their hands

Scotland’s immigrants are as passionate about the future of their adopted nation as anyone else
Culture Minister Ed Vaizey: ‘lack of ethnic minority and black faces on TV is weird’

'Lack of ethnic minority and black faces on TV is weird'

Culture Minister Ed Vaizey calls for immediate action to address the problem
Josephine Dickinson: 'A cochlear implant helped me to discover a new world of sound'

Josephine Dickinson: 'How I discovered a new world of sound'

After going deaf as a child, musician and poet Josephine Dickinson made do with a hearing aid for five decades. Then she had a cochlear implant - and everything changed
Greggs Google fail: Was the bakery's response to its logo mishap a stroke of marketing genius?

Greggs gives lesson in crisis management

After a mishap with their logo, high street staple Greggs went viral this week. But, as Simon Usborne discovers, their social media response was anything but half baked
7 best quadcopters and drones

Flying fun: 7 best quadcopters and drones

From state of the art devices with stabilised cameras to mini gadgets that can soar around the home, we take some flying objects for a spin
Andy Murray: I quit while I’m ahead too often

Andy Murray: I quit while I’m ahead too often

British No 1 knows his consistency as well as his fitness needs working on as he prepares for the US Open after a ‘very, very up and down’ year
Ferguson: In the heartlands of America, a descent into madness

A descent into madness in America's heartlands

David Usborne arrived in Ferguson, Missouri to be greeted by a scene more redolent of Gaza and Afghanistan
BBC’s filming of raid at Sir Cliff’s home ‘may be result of corruption’

BBC faces corruption allegation over its Sir Cliff police raid coverage

Reporter’s relationship with police under scrutiny as DG is summoned by MPs to explain extensive live broadcast of swoop on singer’s home
Lauded therapist Harley Mille still in limbo as battle to stay in Britain drags on

Lauded therapist still in limbo as battle to stay in Britain drags on

Australian Harley Miller is as frustrated by court delays as she is with the idiosyncrasies of immigration law
Lewis Fry Richardson's weather forecasts changed the world. But could his predictions of war do the same?

Lewis Fry Richardson's weather forecasts changed the world...

But could his predictions of war do the same?
Kate Bush asks fans not to take photos at her London gigs: 'I want to have contact with the audience, not iPhones'

'I want to have contact with the audience, not iPhones'

Kate Bush asks fans not to take photos at her London gigs
Under-35s have rated gardening in their top five favourite leisure activities, but why?

Young at hort

Under-35s have rated gardening in their top five favourite leisure activities. But why are so many people are swapping sweaty clubs for leafy shrubs?
Tim Vine, winner of the Funniest Joke of the Fringe award: 'making a quip as funny as possible is an art'

Beyond a joke

Tim Vine, winner of the Funniest Joke of the Fringe award, has nigh-on 200 in his act. So how are they conceived?