Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

William Roache, child abuse and past lives

Judging by his comments, I guess my disability is just a punishment for being a total badass in a previous life?

Saul Sanchez, 48: “He is a very simple man. You know it because he liked to come here and just be with us. He is just a normal person who would eat and drink with us”

'The Slum Pope? He is bigger than that – he is for all the poor people'

Before becoming Pope, Jorge Mario Bergoglio won the hearts of the slum people ministering to the poor and sick

Signs of a rethink on America's War on Drugs

Maryland looks likely to follow Washington and decriminalise marijuana

HIV drugs could 'functionally cure' about 10% of early diagnosed patients

Breakthrough follows reports of a baby girl in the US who was 'cured' after very early treatment

Editorial: A baby step forward in the fight against Aids

HIV/Aids has proved a stubborn problem. Thirty years on from the discovery of the virus – after tens of millions of deaths – there is still only one recorded case of an adult sufferer being cured. (The so-called "Berlin patient" had his entire immune system replaced with that from someone resistant to the disease.)

'Cured' baby remains solitary reminder that genuine solution to HIV is still a long way off

This year marks the 30th anniversary of the discovery of the human immunodeficiency virus (HIV), so it is with great excitement that the Aids community has received the news that a baby has been “cured” of the virus.

Doctor C Everett Koop: Surgeon General who angered US conservatives with his stance on abortion and Aids

Doctor C Everett Koop: Surgeon General who angered US conservatives with his stance on abortion and Aids

Dr C Everett Koop, who died on 25 February at the age of 96, was a leading US health official throughout much of the 1980s who spoke frankly about Aids and railed against smoking. An evangelical Christian, Koop shocked his conservative supporters when he endorsed condoms and sex education to stop the spread of Aids. He was surgeon general for seven years during the Ronald Reagan and George HW Bush administrations. He carried out a crusade to end smoking in the US.

Poverty and poor sanitation are key factors in the spread of the disease

Bill Gates: We cannot stand still on polio, but we can push ahead and end it

Through its judicious use of foreign aid, the UK has helped drive this recent progress

Man charged with murder of gay mayoral candidate

A man has been charged with the murder of an openly gay candidate for mayor of a Mississippi town.

Elton John finds second baby 'much easier' than first

David Furnish has told how he and partner Sir Elton John have found parenthood much easier the second time around.

A couple kisses in Times Square, New York

'Severe epidemic' of sexually transmitted diseases sweeping the US, warn health experts in Valentine’s Day announcement

Centers for Disease Control and Prevention says 20 million new STD cases are diagnosed every year

The ‘Love Is In My Blood’ campaign involves Twitter messages and a video in Piccadilly Circus

Elton John and Ai Weiwei join forces to launch Valentine's Day Aids campaign

Sir Elton John and the Chinese artist Ai Weiwei will today join forces to support a Valentine's Day campaign to raise awareness of Aids.

It was not widely known Mike Freer, a Tory MP, was gay

Mike Freer: A gay Tory MP on why he went public

Mike Freer hesitated for a long time over whether to say anything at all when his fellow MPs argued over whether to legalise gay marriage. He is one of the newer MPs and it was not widely known in Parliament that he is gay.

'Unsafe sexual behaviour' leaves HIV levels among gay men unchanged, says report

“Unsafe sexual behaviour” and a lack of testing is being blamed for a failure to cut the number of cases of HIV among gay and bisexual men in the last decade.

Pop star Madonna cuts the ribbon at the ground breaking ceremony for the Raising Malawi Academy for Girls in Malawi in 2009

Madonna's charitable endeavours rubbished by Malawi education authorities

Madonna’s charitable endeavours were dealt another blow when Malawi’s Education Minister flatly denied the pop star’s claims that her charity had built 10 new schools in the country.

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... then rejected by surviving relatives over fear of infection
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Are censors pandering to homophobia?

US film censors have ruled 'Pride' unfit for under-16s, though it contains no sex or violence
The magic of roundabouts

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Well it was good enough for Ancient Egyptians and Picasso...
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A good time to open a new restaurant in Hong Kong?

As pro-democracy demonstrators hold firm, chef Rowley Leigh, who's in the city to open a new restaurant, says you couldn't hope to meet a nicer bunch
Paris Fashion Week: Karl Lagerfeld leads a feminist riot on 'Boulevard Chanel'

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Lagerfeld leads a feminist riot on 'Boulevard Chanel'
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Simon Calder discovers Bruce Chatwin's Wales

One of the finest one-day walks you could hope for - in Britain
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Make sure the kids stay cosy on cooler autumn nights in this selection of pjs, onesies and nighties
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Five things we learnt from City’s Champions League draw at the Etihad
Martin Hardy: Mike Ashley must act now and end the Alan Pardew reign

Trouble on the Tyne

Ashley must act now and end Pardew's reign at Newcastle, says Martin Hardy
Isis is an hour from Baghdad, the Iraq army has little chance against it, and air strikes won't help

Isis an hour away from Baghdad -

and with no sign of Iraq army being able to make a successful counter-attack
Turner Prize 2014 is frustratingly timid

Turner Prize 2014 is frustratingly timid

The exhibition nods to rich and potentially brilliant ideas, but steps back
Last chance to see: Half the world’s animals have disappeared over the last 40 years

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Why can no one stop hackers putting celebrities' private photos online?