Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

William Roache, child abuse and past lives

Judging by his comments, I guess my disability is just a punishment for being a total badass in a previous life?

Saul Sanchez, 48: “He is a very simple man. You know it because he liked to come here and just be with us. He is just a normal person who would eat and drink with us”

'The Slum Pope? He is bigger than that – he is for all the poor people'

Before becoming Pope, Jorge Mario Bergoglio won the hearts of the slum people ministering to the poor and sick

Signs of a rethink on America's War on Drugs

Maryland looks likely to follow Washington and decriminalise marijuana

HIV drugs could 'functionally cure' about 10% of early diagnosed patients

Breakthrough follows reports of a baby girl in the US who was 'cured' after very early treatment

Editorial: A baby step forward in the fight against Aids

HIV/Aids has proved a stubborn problem. Thirty years on from the discovery of the virus – after tens of millions of deaths – there is still only one recorded case of an adult sufferer being cured. (The so-called "Berlin patient" had his entire immune system replaced with that from someone resistant to the disease.)

'Cured' baby remains solitary reminder that genuine solution to HIV is still a long way off

This year marks the 30th anniversary of the discovery of the human immunodeficiency virus (HIV), so it is with great excitement that the Aids community has received the news that a baby has been “cured” of the virus.

Doctor C Everett Koop: Surgeon General who angered US conservatives with his stance on abortion and Aids

Doctor C Everett Koop: Surgeon General who angered US conservatives with his stance on abortion and Aids

Dr C Everett Koop, who died on 25 February at the age of 96, was a leading US health official throughout much of the 1980s who spoke frankly about Aids and railed against smoking. An evangelical Christian, Koop shocked his conservative supporters when he endorsed condoms and sex education to stop the spread of Aids. He was surgeon general for seven years during the Ronald Reagan and George HW Bush administrations. He carried out a crusade to end smoking in the US.

Poverty and poor sanitation are key factors in the spread of the disease

Bill Gates: We cannot stand still on polio, but we can push ahead and end it

Through its judicious use of foreign aid, the UK has helped drive this recent progress

Man charged with murder of gay mayoral candidate

A man has been charged with the murder of an openly gay candidate for mayor of a Mississippi town.

Elton John finds second baby 'much easier' than first

David Furnish has told how he and partner Sir Elton John have found parenthood much easier the second time around.

A couple kisses in Times Square, New York

'Severe epidemic' of sexually transmitted diseases sweeping the US, warn health experts in Valentine’s Day announcement

Centers for Disease Control and Prevention says 20 million new STD cases are diagnosed every year

The ‘Love Is In My Blood’ campaign involves Twitter messages and a video in Piccadilly Circus

Elton John and Ai Weiwei join forces to launch Valentine's Day Aids campaign

Sir Elton John and the Chinese artist Ai Weiwei will today join forces to support a Valentine's Day campaign to raise awareness of Aids.

It was not widely known Mike Freer, a Tory MP, was gay

Mike Freer: A gay Tory MP on why he went public

Mike Freer hesitated for a long time over whether to say anything at all when his fellow MPs argued over whether to legalise gay marriage. He is one of the newer MPs and it was not widely known in Parliament that he is gay.

'Unsafe sexual behaviour' leaves HIV levels among gay men unchanged, says report

“Unsafe sexual behaviour” and a lack of testing is being blamed for a failure to cut the number of cases of HIV among gay and bisexual men in the last decade.

Pop star Madonna cuts the ribbon at the ground breaking ceremony for the Raising Malawi Academy for Girls in Malawi in 2009

Madonna's charitable endeavours rubbished by Malawi education authorities

Madonna’s charitable endeavours were dealt another blow when Malawi’s Education Minister flatly denied the pop star’s claims that her charity had built 10 new schools in the country.

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The surrealist comedian at the Q Awards in 2010
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News
Russell Brand arriving for the book launch in East London
peopleRussell Brand cancels his book launch debate due to concerns about the make-up of the panel
Sport
Christiano Ronaldo enjoys his opening goal
champions leagueLiverpool 0 Real Madrid 3: Ronaldo and Benzema run Reds ragged to avenge thrashing from their last visit to Anfield
Arts and Entertainment
Awesome foursome: Sam Smith shows off his awards
music22-year-old confirms he is 2014’s breakout British music success
Life and Style
Six of the 76 Goats' cheese samples contained a significant amount of sheep's cheese
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Arts and Entertainment
Contestants during this summer's Celebrity Big Brother grand finale
tvBroadcaster attempts to change its image following sale to American media group
Extras
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Arts and Entertainment
Sir Nicholas Serota has been a feature in the Power 100 top ten since its 2002 launch
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Arts and Entertainment
Sarah Dales attempts to sell British Breeze in the luxury scent task
tvReview: 'Apprentice' candidate on the verge of tears as they were ejected from the boardroom
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Call me Superman: one of many unusual names chosen by Chinese students
newsChinese state TV offers advice for citizens picking a Western moniker
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Prices correct as of 17 October 2014
How could three tourists have been battered within an inch of their lives by a burglar in a plush London hotel?

A crime that reveals London's dark heart

How could three tourists have been battered within an inch of their lives by a burglar in a plush London hotel?
Meet 'Porridge' and 'Vampire': Chinese state TV is offering advice for citizens picking a Western moniker

Lost in translation: Western monikers

Chinese state TV is offering advice for citizens picking a Western moniker. Simon Usborne, who met a 'Porridge' and a 'Vampire' while in China, can see the problem
Handy hacks that make life easier: New book reveals how to rid your inbox of spam, protect your passwords and amplify your iPhone

Handy hacks that make life easier

New book reveals how to rid your email inbox of spam, protect your passwords and amplify your iPhone with a loo-roll
KidZania lets children try their hands at being a firefighter, doctor or factory worker for the day

KidZania: It's a small world

The new 'educational entertainment experience' in London's Shepherd's Bush will allow children to try out the jobs that are usually undertaken by adults, including firefighter, doctor or factory worker
Renée Zellweger's real crime has been to age in an industry that prizes women's youth over humanity

'Renée Zellweger's real crime was to age'

The actress's altered appearance raised eyebrows at Elle's Women in Hollywood awards on Monday
From Cinderella to The Jungle Book, Disney plans live-action remakes of animated classics

Disney plans live-action remakes of animated classics

From Cinderella to The Jungle Book, Patrick Grafton-Green wonders if they can ever recapture the old magic
Thousands of teenagers to visit battlefields of the First World War in new Government scheme

Pupils to visit First World War battlefields

A new Government scheme aims to bring the the horrors of the conflict to life over the next five years
The 10 best smartphone accessories

Make the most of your mobile: 10 best smartphone accessories

Try these add-ons for everything from secret charging to making sure you never lose your keys again
Mario Balotelli substituted at half-time against Real Madrid: Was this shirt swapping the real reason?

Liverpool v Real Madrid

Mario Balotelli substituted at half-time. Was shirt swapping the real reason?
West Indies tour of India: Hurricane set to sweep Windies into the shadows

Hurricane set to sweep Windies into the shadows

Decision to pull out of India tour leaves the WICB fighting for its existence with an off-field storm building
Indiana serial killer? Man arrested for murdering teenage prostitute confesses to six other murders - and police fear there could be many more

A new American serial killer?

Police fear man arrested for murder of teen prostitute could be responsible for killing spree dating back 20 years
Sweetie, the fake 10-year-old girl designed to catch online predators, claims her first scalp

Sting to trap paedophiles may not carry weight in UK courts

Computer image of ‘Sweetie’ represented entrapment, experts say
Fukushima nuclear crisis: Evacuees still stuck in cramped emergency housing three years on - and may never return home

Return to Fukushima – a land they will never call home again

Evacuees still stuck in cramped emergency housing three years on from nuclear disaster
Wildlife Photographer of the Year: Intimate image of resting lions claims top prize

Wildlife Photographer of the Year

Intimate image of resting lions claims top prize
Online petitions: Sign here to change the world

Want to change the world? Just sign here

The proliferation of online petitions allows us to register our protests at the touch of a button. But do they change anything?