News The eye of the storm: Speakes in the White House in 1982

An assassination attempt plunged Larry Speakes into the brightest of national spotlights as chief spokesman for President Ronald Reagan. When Reagan’s press secretary James Brady was severely wounded in the 1981 attempt on the president’s life, Speakes was thrust into the eye of the storm. As White House spokesman for six years, a long tenure in the sensitive post, he was credited with 2,000 news media briefings.

Merrill Lynch delays Manhattan building project

The credit market crisis is forcing Wall Street firms to rip up even some of their best-laid plans, the latest example being Merrill Lynch's decision to postpone the building of a hi-tech skyscraper in midtown Manhattan.

AstraZeneca closes in on £600m deal for CAT

Cambridge Antibody Technology (CAT) is set to become the latest biotech group to lose its independence, selling out to AstraZeneca in a deal worth about £600m.

Boots blames rising interest rates for slowdown in sales

Boots sent the first signal that the retail sector had failed to bounce back after a disappointing Christmas yesterday with a profit warning that knocked 4 per cent off its share price. Just six weeks after reassuring the City that profits to the end of March were on track, the group admitted its sales growth had dried amid a wider slowdown on the high street.

Market Report: Amvescap investors make a dash for the exit

Investors scrambled to exit Amvescap yesterday amid growing worry that next week's third-quarter results from the fund management giant are set to disappoint. The latest anxiety to surround the company was caused by a note from Merrill Lynch in which the broker slashed its earnings forecasts for Amvescap. Merrill cut its estimates by 4 per cent for the current year and 9 per cent for 2005, sending shares in the fund manager tumbling 11p to 280.5p.

Banker in sex-bias case denies she was 'pampered princess'

A senior banker suing Merrill Lynch in a multimillion-pound sex discrimination case denied yesterday that she was "a pampered princess".

Market Report: 'Sell' note puts pressure on Bradford & Bingley

Merrill Lynch certainly did not pull any punches in its investment note on Bradford & Bingleyyesterday. It bluntly told investors to sell the stock and set a fair value target of 254p.

Market Report: Broker soothes fears over Kingfisher's Easter

Worries about trading at Kingfisher during the all-important Easter weekend have been exaggerated. That was the message from Merrill Lynch to its clients yesterday after a meeting with Duncan Tatton-Brown, the retailer's finance director.

Fund managers turn more bullish on shares

Club of Tigers gets ready to roar
David Moyes and Louis van Gaal
New Zealand fly-half Aaron Cruden pictured in The Zookeeper's Son on a late-night drinking session
A cabin crew member photographed the devastation after one flight
Life and Style
food + drink
Former Governor of Alaska Sarah Palin, left, with her daughter, Bristol
newsShe's 'proud' of her eldest daughter, who 'punched host in the face'
Arts and Entertainment
musicBand's first new record for 20 years has some tough acts to follow
Rob Merrick's Lobby Journalists were playing Ed Balls' Labour Party MPs. The match is an annual event which takes place ahead of the opening of the party conference
newsRob Merrick insistes 'Ed will be hurting much more than me'
A new app has been launched that enables people to have a cuddle from a stranger
voicesMaybe the new app will make it more normal to reach out to strangers
Liam Payne has attacked the media for reporting his tweet of support to Willie Robertson and the subsequent backlash from fans
peopleBut One Direction star insists he is not homophobic
Life and Style
healthFor Pure-O OCD sufferers this is a reality they live in
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Prices correct as of 17 September 2014
A roller-coaster tale from the 'voice of a generation'

Not That Kind of Girl:

A roller-coaster tale from 'voice of a generation' Lena Dunham
London is not bedlam or a cradle of vice. In fact it, as much as anywhere, deserves independence

London is not bedlam or a cradle of vice

In fact it, as much as anywhere, deserves independence
Vivienne Westwood 'didn’t want' relationship with Malcolm McLaren

Vivienne Westwood 'didn’t want' relationship with McLaren

Designer 'felt pressured' into going out with Sex Pistols manager
Jourdan Dunn: Model mother

Model mother

Jordan Dunn became one of the best-paid models in the world
Apple still coolest brand – despite U2 PR disaster

Apple still the coolest brand

Despite PR disaster of free U2 album
Scottish referendum: The Yes vote was the love that dared speak its name, but it was not to be

Despite the result, this is the end of the status quo

Boyd Tonkin on the fall-out from the Scottish referendum
Manolo Blahnik: The high priest of heels talks flats, Englishness, and why he loves Mary Beard

Manolo Blahnik: Flats, Englishness, and Mary Beard

The shoe designer who has been dubbed 'the patron saint of the stiletto'
The Beatles biographer reveals exclusive original manuscripts of some of the best pop songs ever written

Scrambled eggs and LSD

Behind The Beatles' lyrics - thanks to Hunter Davis's original manuscript copies
'Normcore' fashion: Blending in is the new standing out in latest catwalk non-trend

'Normcore': Blending in is the new standing out

Just when fashion was in grave danger of running out of trends, it only went and invented the non-trend. Rebecca Gonsalves investigates
Dance’s new leading ladies fight back: How female vocalists are now writing their own hits

New leading ladies of dance fight back

How female vocalists are now writing their own hits
Mystery of the Ground Zero wedding photo

A shot in the dark

Mystery of the wedding photo from Ground Zero
His life, the universe and everything

His life, the universe and everything

New biography sheds light on comic genius of Douglas Adams
Save us from small screen superheroes

Save us from small screen superheroes

Shows like Agents of S.H.I.E.L.D are little more than marketing tools
Reach for the skies

Reach for the skies

From pools to football pitches, rooftop living is looking up
These are the 12 best hotel spas in the UK

12 best hotel spas in the UK

Some hotels go all out on facilities; others stand out for the sheer quality of treatments