News The eye of the storm: Speakes in the White House in 1982

An assassination attempt plunged Larry Speakes into the brightest of national spotlights as chief spokesman for President Ronald Reagan. When Reagan’s press secretary James Brady was severely wounded in the 1981 attempt on the president’s life, Speakes was thrust into the eye of the storm. As White House spokesman for six years, a long tenure in the sensitive post, he was credited with 2,000 news media briefings.

Merrill Lynch delays Manhattan building project

The credit market crisis is forcing Wall Street firms to rip up even some of their best-laid plans, the latest example being Merrill Lynch's decision to postpone the building of a hi-tech skyscraper in midtown Manhattan.

AstraZeneca closes in on £600m deal for CAT

Cambridge Antibody Technology (CAT) is set to become the latest biotech group to lose its independence, selling out to AstraZeneca in a deal worth about £600m.

Boots blames rising interest rates for slowdown in sales

Boots sent the first signal that the retail sector had failed to bounce back after a disappointing Christmas yesterday with a profit warning that knocked 4 per cent off its share price. Just six weeks after reassuring the City that profits to the end of March were on track, the group admitted its sales growth had dried amid a wider slowdown on the high street.

Market Report: Amvescap investors make a dash for the exit

Investors scrambled to exit Amvescap yesterday amid growing worry that next week's third-quarter results from the fund management giant are set to disappoint. The latest anxiety to surround the company was caused by a note from Merrill Lynch in which the broker slashed its earnings forecasts for Amvescap. Merrill cut its estimates by 4 per cent for the current year and 9 per cent for 2005, sending shares in the fund manager tumbling 11p to 280.5p.

Banker in sex-bias case denies she was 'pampered princess'

A senior banker suing Merrill Lynch in a multimillion-pound sex discrimination case denied yesterday that she was "a pampered princess".

Market Report: 'Sell' note puts pressure on Bradford & Bingley

Merrill Lynch certainly did not pull any punches in its investment note on Bradford & Bingleyyesterday. It bluntly told investors to sell the stock and set a fair value target of 254p.

Market Report: Broker soothes fears over Kingfisher's Easter

Worries about trading at Kingfisher during the all-important Easter weekend have been exaggerated. That was the message from Merrill Lynch to its clients yesterday after a meeting with Duncan Tatton-Brown, the retailer's finance director.

Fund managers turn more bullish on shares

Club of Tigers gets ready to roar
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Oscar Pistorius sentencing: The athlete's wealth and notoriety have provoked a long overdue debate on South African prisons

'They poured water on, then electrified me...'

If Oscar Pistorius is sent to jail, his experience will not be that of other inmates
James Wharton: The former Guard now fighting discrimination against gay soldiers

The former Guard now fighting discrimination against gay soldiers

Life after the Army has brought new battles for the LGBT activist James Wharton
Ebola in the US: Panic over the virus threatens to infect President Obama's midterms

Panic over Ebola threatens to infect the midterms

Just one person has died, yet November's elections may be affected by what Republicans call 'Obama's Katrina', says Rupert Cornwell
Premier League coaches join the RSC to swap the tricks of their trades

Darling, you were fabulous! But offside...

Premier League coaches are joining the RSC to learn acting skills, and in turn they will teach its actors to play football. Nick Clark finds out why
How to dress with authority: Kirsty Wark and Camila Batmanghelidjh discuss the changing role of fashion in women's workwear

How to dress with authority

Kirsty Wark and Camila Batmanghelidjh discuss the changing role of fashion in women's workwear
New book on Joy Division's Ian Curtis sheds new light on the life of the late singer

New book on Ian Curtis sheds fresh light on the life of the late singer

'Joy Division were making art... Ian was for real' says author Jon Savage
Sean Harris: A rare interview with British acting's secret weapon

Sean Harris: A rare interview with British acting's secret weapon

The Bafta-winner talks Hollywood, being branded a psycho, and how Barbra Streisand is his true inspiration
Tim Minchin, interview: The musician, comedian and world's favourite ginger is on scorching form

Tim Minchin interview

For a no-holds-barred comedian who is scathing about woolly thinking and oppressive religiosity, he is surprisingly gentle in person
Boris Johnson's boozing won't win the puritan vote

Boris's boozing won't win the puritan vote

Many of us Brits still disapprove of conspicuous consumption – it's the way we were raised, says DJ Taylor
Ash frontman Tim Wheeler reveals how he came to terms with his father's dementia

Tim Wheeler: Alzheimer's, memories and my dad

Wheeler's dad suffered from Alzheimer's for three years. When he died, there was only one way the Ash frontman knew how to respond: with a heartfelt solo album
Hugh Bonneville & Peter James: 'Peter loves his classic cars; I've always pootled along fine with a Mini Metro. I think I lack his panache'

How We Met: Hugh Bonneville & Peter James

'Peter loves his classic cars; I've always pootled along fine with a Mini Metro. I think I lack his panache'
Bill Granger recipes: Our chef's heavenly crab dishes don't need hours of preparation

Bill Granger's heavenly crab recipes

Scared off by the strain of shelling a crab? Let a fishmonger do the hard work so you can focus on getting the flavours right
Radamel Falcao: How faith and love drive the Colombian to glory

Radamel Falcao: How faith and love drive the Colombian to glory

After a remarkable conversion from reckless defender to prolific striker, Monaco's ace says he wants to make his loan deal at Old Trafford permanent
Terry Venables: Premier League managers must not be allowed to dictate who plays and who does not play for England

Terry Venables column

Premier League managers must not be allowed to dictate who plays and who does not play for England
The Inside Word: Brendan Rodgers looks to the future while Roy Hodgson is ghost of seasons past

Michael Calvin's Inside Word

Brendan Rodgers looks to the future while Roy Hodgson is ghost of seasons past