News Reading a novel may boost brain functionality for days, new research has found

Reading a gripping novel causes biological changes in the brain which last for days as the mind is transported into the body of the protagonist

Leading article: The unacknowledged epidemic of our age

Dementia is still barely understood and sufferers often slip through gaps in the system

Carol Jennings: 'Gradually it [Alzheimer's disease] was going through the family. It seemed like each year another one would have developed it'

'Most of my family had dementia. I knew I should tell someone'

Peter Popham meets a remarkable family from Nottingham who changed the way scientists thought about Alzheimer's – and offered hope to millions of people

Babyjabs.co.uk to remove MMR autism claim

A website offering parents advice on childhood immunisation has been ordered to remove information about the MMR vaccine after renewing claims that it could be linked to autism.

Album: Antony and the Johnsons, Cut the World (Rough Trade)

The notion of transformation has always been fundamental to the work of Antony Hegarty, often in trans-gender and even trans-species terms. He's the ugly duckling that turned into the magnificent swan – and on Cut the World, that swan gets to drift all the more elegantly across a lake of full-scale orchestral arrangements, which themselves transform some of his earlier songs into more fabulous creations.

James Holmes was identified as a possible safety threat by his own psychiatrist

Colorado cinema Batman massacre accused James Holmes was identified as threat by his psychiatrist

Development adds weight to speculation that the mass shooting could have been avoided

Coffee can help control Parkinson's tremors, shows research

Coffee can help tame the tremors caused by Parkinson's disease, research has shown.

Single pill could be used to treat Alzheimer's, Parkinson's and multiple sclerosis

A single pill has the potential to treat multiple brain conditions including Alzheimer's, Parkinson's and multiple sclerosis, it has been revealed.

The apartment where James Holmes is believed to have planned his attack was the scene of a massive security operation tonight

The killer: 'Loner' medical student who opened fire and left his nearby flat booby-trapped

James Holmes described himself as “a quiet and easy-going medical student” on the application form he filled out last May before renting a third-floor apartment in a brick-walled building a stone's throw from the University of Colorado's sprawling hospital campus.

Man missing in desert for three weeks survived on diet of frogs and roots

An autistic man survived in the desert for three weeks on a diet of frogs and roots, US authorities have said.

Mystery disease kills 61 children in Cambodia

Health chiefs in Cambodia are searching for the cause of a mystery disease that has killed more than 60 children over the past three months.

John Simpson with partner Dee Kruger and son Rafe

BBC broadcaster John Simpson says he plans to commit suicide rather than allow young son to see him as a 'gibbering wreck' in old age

The veteran correspondent said "I don’t want my 6 year-old son to have his only memory of me as a gibbering wreck"

Man dies in Southsea 'landsurfing' accident

A 26-year-old man has died after hitting a concrete post while "landsurfing" - a new form of skateboarding.

Care home patients with dementia being 'denied sex'

Care home patients suffering from dementia should be allowed to participate in consensual sex, experts said.

Horse Man: Rupert Isaacson developed his son's language skills in the saddle. A charity using his approach is to be launched in the UK

How riding a horse taught a boy to speak

A father has found a therapy that can transform autistic children

Husband and wife team Geoff and Nargis Soppet at the Autism Show, ExCel, London

World's first autism show offers a chance to shine

Event will bring disability into the open and celebrate its links with creativity

News
i100 In this video, the late actor Leonard Nimoy explains how he decided to use the gesture for his character
Arts and Entertainment
Secrets of JK Rowling's Harry Potter workings have been revealed in a new bibliography
arts + ents
News
Down-to-earth: Winstone isn't one for considering his 'legacy'
people
News
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It was only when he left his post Tony Blair's director of communications that Alastair Campbell has published books
people
Sport
Eden Hazard enjoys a laugh at Chelsea’s Cobham training ground this week
football Eden Hazard exclusive interview
Life and Style
The new model would be a “pedal assist” bike in which the rider’s strength is augmented by the engine on hills and when they want to go fast
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Independent Travel
Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
Burgundy, the River Rhone & Provence
Prague, Budapest and Vienna
Lake Garda
3.	Provence 6 nights B&B by train from £599pp
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HIV pill: Scientists hail discovery of 'game-changer' that cuts the risk of infection among gay men by 86%

Scientists hail daily pill that protects against HIV infection

Breakthrough in battle against global scourge – but will the NHS pay for it?
How we must adjust our lifestyles to nature: Welcome to the 'Anthropocene', the human epoch

Time to play God

Welcome to the 'Anthropocene', the human epoch where we may need to redefine nature itself
MacGyver returns, but with a difference: Handyman hero of classic 1980s TV series to be recast as a woman

MacGyver returns, but with a difference

Handyman hero of classic 1980s TV series to be recast as a woman
Tunnel renaissance: Why cities are hiding roads down in the ground

Tunnel renaissance

Why cities are hiding roads underground
'Backstreet Boys - Show 'Em What You're Made Of': An affectionate look at five middle-aged men

Boys to men

The Backstreet Boys might be middle-aged, married and have dodgy knees, but a heartfelt documentary reveals they’re not going gently into pop’s good night
Crufts 2015: Should foreign dogs be allowed to compete?

Crufts 2015

Should foreign dogs be allowed to compete?
10 best projectors

How to make your home cinema more cinematic: 10 best projectors

Want to recreate the big-screen experience in your sitting room? IndyBest sizes up gadgets to form your film-watching
Manchester City 1 Barcelona 2 player ratings: Luis Suarez? Lionel Messi? Joe Hart? Who was the star man?

Manchester City vs Barcelona player ratings

Luis Suarez? Lionel Messi? Joe Hart? Who was the star man at the Etihad?
Arsenal vs Monaco: Monaco - the making of Gunners' manager Arsene Wenger

Monaco: the making of Wenger

Jack Pitt-Brooke speaks to former players and learns the Frenchman’s man-management has always been one of his best skills
Cricket World Cup 2015: Chris Gayle - the West Indies' enigma lives up to his reputation

Chris Gayle: The West Indies' enigma

Some said the game's eternal rebel was washed up. As ever, he proved he writes the scripts by producing a blistering World Cup innings
In Ukraine a dark world of hybrid warfare and murky loyalties prevails

In Ukraine a dark world of hybrid warfare

This war in the shadows has been going on since the fall of Mr Yanukovych
'Birdman' and 'Bullets Over Broadway': Homage or plagiarism?

Homage or plagiarism?

'Birdman' shares much DNA with Woody Allen's 'Bullets Over Broadway'
Broadchurch ends as damp squib not even David Tennant can revive

A damp squib not even David Tennant can revive

Broadchurch, Series 2 finale, review
A Koi carp breeding pond, wall-mounted iPads and a bathroom with a 'wellness' shower: inside the mansion of Germany's 'Bishop of Bling'

Inside the mansion of Germany's 'Bishop of Bling'

A Koi carp breeding pond, wall-mounted iPads and a bathroom with a 'wellness' shower