Sport Seattle, led by Russell Wilson, are favourites to win next month's Super Bowl

For devotees of the NFL, this is as good as it gets – the divisional round of the play-offs, four games pitting the regular season’s finest against four challengers already battle-hardened by victory in last weekend’s ever-treacherous wild-card round. And in 2014 there’s an extra twist: the prospect that one of the longest, most painful droughts in US sport might be near an end.

Grape extract could fight cancer

A supplement made from grape seeds can destroy leukaemia cells, according to scientists at the University of Kentucky in Philadelphia.

New migraine treatment has fewer side effects

A new treatment for migraine that is as effective as existing drugs but with fewer side effects will bring fresh hope to millions of sufferers, scientists said yesterday.

Baseball: Lidge ends Phillies' long wait for World Series glory

Half a million fans are expected to jam the streets of downtown Philadelphia today in celebration of the Phillies' first World Series title since 1980, and the first major league championship in any sport by a city team in a quarter of a century.

Baseball: Philadelphia capture World Series

The Philadelphia Phillies have won the World Series after beating the Tampa Bay Rays in last night's rain-delayed Game Five.

The man who invented sex

Harold Robbins was the man who invented sex. Not the actual act, nor its literary depiction, but the way it was represented in mass-market fiction. The "godfather of the airport novel" if not the creator of the bonkbuster changed the face of post-war popular fiction with steamy tales such as The Betsy, The Lonely Lady, The Pirate and his 1961 classic, The Carpetbaggers.

David Lynch: 'They murdered my first movie'

Today, his films are considered cinematic masterworks – yet David Lynch is still smarting from criticism of his debut, Eraserhead. On the eve of its re-release, the director talks to Sophie Morris

Brothers admit selling corpses in Philadelphia

Two brothers who ran a Philadelphia funeral home have pleaded guilty to selling corpses to a company that trafficked in stolen body parts, including those of "Masterpiece Theatre" host Alistair Cooke.

Enzyme discovery may hold key to cancer treatments

A major discovery could open the door to "one-fits-all" cancer drugs that can tackle many different forms of the disease.

Robert Hazard: 'Girls Just Want to Have Fun' writer

When Robert Hazard dashed off "Girls Just Want to Have Fun" in 20 minutes in the shower, he never expected what he called this "kind of silly song" to become a worldwide smash for him, or anybody else for that matter.

Album: Dr Dog, Fate (Park the Van)

Album number five for the Philadelphia-based quintet and critical opinion Stateside is divided: 'Entertainment Weekly' declared 'Fate' an "expertly honed tribute to the past", while 'Slant' magazine called it "phenomenally uninteresting".

Preview: Melody Gardot, Bloomsbury Theatre, London

When Melody Gardot sings "It's a miracle I'm alive, I do not think I can survive", she's singing from the heart. The lyrics come from the first song she wrote, in the aftermath of the traffic accident that almost killed her. Today, '"Some Lessons" is still the song that defines her.

Bobby Durham: Drummer at the heart of jazz

Although his drumming was at the heart of jazz, Bobby Durham will perhaps best be remembered as one of the very few musicians that Duke Ellington actually fired (Charlie Mingus was another). Continuously in demand throughout his career, Durham appeared on more recordings than almost any other drummer, and was at his most eminent in his time with the Oscar Peterson Trio.

Ira Tucker: Dixie Hummingbirds lead singer

Ira Tucker fronted the gospel group the Dixie Hummingbirds for 70 years. His soulful singing and flamboyant performances influenced James Brown and Jackie Wilson, while the Drifters and the Temptations took the template of the Dixie Hummingbirds into the charts in the Fifties, Sixties and Seventies.

Solomon Burke: last of the great soul men

He's a 30-stone ladies' man with 89 grandchildren; a mortician-turned-preacher who claims to be a king; a friend of Malcolm X who played for the Ku Klux Klan... Ahead of his performance at Glastonbury tonight, Solomon Burke, soul legend, tells his amazing, contradictory life story
Career Services

Day In a Page

Independent Travel
Vietnam & Cambodia
Pompeii, Capri & the Bay of Naples
Bruges
India & Nepal
Japan
Berlin, Dresden, Meissen & Colditz
Prices correct as of 17 October 2014
Two super-sized ships have cruised into British waters, but how big can these behemoths get?

Super-sized ships: How big can they get?

Two of the largest vessels in the world cruised into UK waters last week
British doctors on brink of 'cure' for paralysis with spinal cord treatment

British doctors on brink of cure for paralysis

Sufferers can now be offered the possibility of cure thanks to a revolutionary implant of regenerative cells
Let's talk about loss

We need to talk about loss

Secrecy and silence surround stillbirth
Will there be an all-female mission to Mars?

Will there be an all-female mission to Mars?

Women may be better suited to space travel than men are
Oscar Pistorius sentencing: The athlete's wealth and notoriety have provoked a long overdue debate on South African prisons

'They poured water on, then electrified me...'

If Oscar Pistorius is sent to jail, his experience will not be that of other inmates
James Wharton: The former Guard now fighting discrimination against gay soldiers

The former Guard now fighting discrimination against gay soldiers

Life after the Army has brought new battles for the LGBT activist James Wharton
Ebola in the US: Panic over the virus threatens to infect President Obama's midterms

Panic over Ebola threatens to infect the midterms

Just one person has died, yet November's elections may be affected by what Republicans call 'Obama's Katrina', says Rupert Cornwell
Premier League coaches join the RSC to swap the tricks of their trades

Darling, you were fabulous! But offside...

Premier League coaches are joining the RSC to learn acting skills, and in turn they will teach its actors to play football. Nick Clark finds out why
How to dress with authority: Kirsty Wark and Camila Batmanghelidjh discuss the changing role of fashion in women's workwear

How to dress with authority

Kirsty Wark and Camila Batmanghelidjh discuss the changing role of fashion in women's workwear
New book on Joy Division's Ian Curtis sheds new light on the life of the late singer

New book on Ian Curtis sheds fresh light on the life of the late singer

'Joy Division were making art... Ian was for real' says author Jon Savage
Sean Harris: A rare interview with British acting's secret weapon

Sean Harris: A rare interview with British acting's secret weapon

The Bafta-winner talks Hollywood, being branded a psycho, and how Barbra Streisand is his true inspiration
Tim Minchin, interview: The musician, comedian and world's favourite ginger is on scorching form

Tim Minchin interview

For a no-holds-barred comedian who is scathing about woolly thinking and oppressive religiosity, he is surprisingly gentle in person
Boris Johnson's boozing won't win the puritan vote

Boris's boozing won't win the puritan vote

Many of us Brits still disapprove of conspicuous consumption – it's the way we were raised, says DJ Taylor
Ash frontman Tim Wheeler reveals how he came to terms with his father's dementia

Tim Wheeler: Alzheimer's, memories and my dad

Wheeler's dad suffered from Alzheimer's for three years. When he died, there was only one way the Ash frontman knew how to respond: with a heartfelt solo album