Sport Seattle, led by Russell Wilson, are favourites to win next month's Super Bowl

For devotees of the NFL, this is as good as it gets – the divisional round of the play-offs, four games pitting the regular season’s finest against four challengers already battle-hardened by victory in last weekend’s ever-treacherous wild-card round. And in 2014 there’s an extra twist: the prospect that one of the longest, most painful droughts in US sport might be near an end.

Woman dies after cosmetic treatment

A British woman died after travelling to America for a cosmetic buttock treatment.

Live-in helper was 'Jihad Jane' terrorist

A US woman who was the live-in caretaker for her boyfriend's elderly father, told a judge that she had worked secretly online under the name Jihad Jane to support Islamic terrorists and had moved overseas to further her plan to kill a Swedish artist who had offended Muslims.

Video: Gas explosion caught on film

One utility worker has been killed after a huge blast high pressure gas main in Philadelphia, USA.

Stem cells clue to beating baldness

Activating dormant stem cells in the scalp could be the key to banishing baldness, scientists believe.

Lemon curd cheesecake

Serves 4

Laszlo Polgar

Laszlo Polgar, who died on 19 September 2010 aged 63, was a Hungarian bass and member of the Zurich Opera. His most famous role was probably that of Bluebeard in Bela Bartok's Bluebeard's Castle, for which he won a Grammy Award for best opera recording in 1999 along with soprano Jessye Norman, conductor Pierre Boulez and the Chicago Symphony Orchestra.

R.E.S.P.E.C.T. Find out what it means to Condi

Former US secretary of state hits the stage with Aretha Franklin

How pre-season jollies got turned into serious money-makers

They used to be for sweating off a summer of excess but now club tours are all about building the brand

Manchester United win pre-season friendly

Manchester United beat the Philadelphia Union 1-0 yesterday in a scrappy game against Major League Soccer's newest team.

Jeremy Laurance: The biggest puzzle is the rise in cases in the past 30 years

The authors dismissed suggestions that lifestyle changes were behind the 12-fold increase

Drugs 'improve social skills of autism sufferers'

Scientists are opening a new front against autism by using drugs to alter brain chemistry that may ameliorate the worst effects of the condition.

Hernandez completes Manchester United transfer

Manchester United have completed the deal to sign Javier Hernandez after the Mexico striker was granted a work permit today.

US vice president Joe Biden's son suffers a stroke

The elder son of US vice president Joe Biden was recovering in hospital today after suffering a stroke.

Man, 80, strangled wife over 'affair'

An elderly man has admitted strangling his wife in their suburban Philadelphia apartment after he accused her of infidelity and she laughed at him.

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Burgundy, the River Rhone & Provence – MS Swiss Corona - seven nights from £999pp
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'I’ll tell you what I would not serve - lamb and potatoes': US ambassador hits out at stodgy British food served at diplomatic dinners

'I’ll tell you what I would not serve - lamb and potatoes'

US ambassador hits out at stodgy British food
Radio Times female powerlist: A 'revolution' in TV gender roles

A 'revolution' in TV gender roles

Inside the Radio Times female powerlist
Endgame: James Frey's literary treasure hunt

James Frey's literary treasure hunt

Riddling trilogy could net you $3m
Fitbit: Because the tingle feels so good

Fitbit: Because the tingle feels so good

What David Sedaris learnt about the world from his fitness tracker
Saudis risk new Muslim division with proposal to move Mohamed’s tomb

Saudis risk new Muslim division with proposal to move Mohamed’s tomb

Second-holiest site in Islam attracts millions of pilgrims each year
Alexander Fury: The designer names to look for at fashion week this season

The big names to look for this fashion week

This week, designers begin to show their spring 2015 collections in New York
Will Self: 'I like Orwell's writing as much as the next talented mediocrity'

'I like Orwell's writing as much as the next talented mediocrity'

Will Self takes aim at Orwell's rules for writing plain English
Meet Afghanistan's middle-class paint-ballers

Meet Afghanistan's middle-class paint-ballers

Toy guns proving a popular diversion in a country flooded with the real thing
Al Pacino wows Venice

Al Pacino wows Venice

Ham among the brilliance as actor premieres two films at festival
Neil Lawson Baker interview: ‘I’ve gained so much from art. It’s only right to give something back’.

Neil Lawson Baker interview

‘I’ve gained so much from art. It’s only right to give something back’.
The other Mugabe who is lining up for the Zimbabwean presidency

The other Mugabe who is lining up for the Zimbabwean presidency

Wife of President Robert Mugabe appears to have her sights set on succeeding her husband
The model of a gadget launch: Cultivate an atmosphere of mystery and excitement to sell stuff people didn't realise they needed

The model for a gadget launch

Cultivate an atmosphere of mystery and excitement to sell stuff people didn't realise they needed
Alice Roberts: She's done pretty well, for a boffin without a beard

She's done pretty well, for a boffin without a beard

Alice Roberts talks about her new book on evolution - and why her early TV work drew flak from (mostly male) colleagues
Get well soon, Joan Rivers - an inspiration, whether she likes it or not

Get well soon, Joan Rivers

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Doctor Who Into the Dalek review: A classic sci-fi adventure with all the spectacle of a blockbuster

A fresh take on an old foe

Doctor Who Into the Dalek more than compensated for last week's nonsensical offering