Risk ought not prevent research into the 1918 flu

Research pushes back the frontiers of human knowledge

Share

It may come as a surprise to some that one of the most feared infectious diseases happens to be influenza. The flu virus has a remarkable ability to mutate into more deadly forms and it is easily transmitted from one person to another through respiratory droplets carried in the air.

Indeed, one of the most notorious pandemics in history was the outbreak of Spanish flu at the end of the First World War. Somewhere in the region of 50 million people worldwide were estimated to have died of the viral infection.

When the frozen corpses of some of the victims of the 1918 pandemic were exhumed from the Arctic permafrost a decade or so ago, scientists managed to extract fragments of the virus and reconstruct its entire genome.

Now they have gone a stage further and rebuilt a near-copy of the 1918 influenza.

In the latest study, the scientists went on to infect laboratory ferrets (the only good animal model of human influenza) with the reconstructed virus and even tinkered with its genome to show that its virulence or infectiousness can be enhanced further.

This kind of research, known as “gain of function” studies, has already met with some disapproval by other scientists who are not convinced that it is completely safe from some kind of accidental or deliberate release. Their concerns led to a voluntary moratorium on the research. This has, however, since been lifted by the flu scientists, who are convinced that there are benefits from discovering what makes the influenza virus so dangerous.

They are taking a risk. An outbreak could be catastrophic, and every possible precaution must be taken. Moreover, the scientists themselves have a duty to further educate the public about what exactly it is they are trying to achieve. But this kind of research pushes back the frontiers of human knowledge and may, in later application, prove of great use to humankind. Risk ought not prevent it.

React Now

Latest stories from i100
iJobs Job Widget
iJobs General

Education Recruitment Consultant- Learning Support

£18000 - £30000 per annum + Generous commission scheme: AER Teachers: Thames T...

All Primary NQT's

£100 - £120 per day + per day: Randstad Education Leeds: Description Calling a...

DT Teacher - Food Technology

£100 - £145 per day + Pension and travel: Randstad Education Maidstone: SUPPLY...

Supply Teachers Needed in Thetford

£21000 - £35000 per annum: Randstad Education Cambridge: Supply teachers neede...

Day In a Page

Read Next
 

Why black cats make amazing pets, and take good selfies too

Felicity Morse
Children of a bygone era  

Kids these days aren't what they used to be — they're a lot better. So why the fuss?

Archie Bland
Save the tiger: The day America’s love of backyard tigers led to a horrific bloodbath

The day America’s love of backyard tigers led to a horrific bloodbath

With only six per cent of the US population of these amazing big cats held in zoos, the Zanesville incident in 2011 was inevitable
Samuel Beckett's biographer reveals secrets of the writer's time as a French Resistance spy

How Samuel Beckett became a French Resistance spy

As this year's Samuel Beckett festival opens in Enniskillen, James Knowlson, recalls how the Irish writer risked his life for liberty and narrowly escaped capture by the Gestapo
We will remember them: relatives still honour those who fought in the Great War

We will remember them

Relatives still honour those who fought in the Great War
Star Wars Episode VII is being shot on film - and now Kodak is launching a last-ditch bid to keep celluloid alive

Kodak's last-ditch bid to keep celluloid alive

Director J J Abrams and a few digital refuseniks shoot movies on film. Simon Usborne wonders what the fuss is about
Once stilted and melodramatic, Hollywood is giving acting in video games a makeover

Acting in video games gets a makeover

David Crookes meets two of the genre's most popular voices
Could our smartphones soon be diagnosing diseases via Health Kit and Google Fit?

Could smartphones soon be diagnosing diseases?

Health Kit and Google Fit have been described as "the beginning of a health revolution"
Ryanair has turned on the 'charm offensive' but can we learn to love the cut-price carrier again?

Can we learn to love Ryanair again?

Four recent travellers give their verdicts on the carrier's improved customer service
Billionaire founder of Spanx launches range of jeans that offers

Spanx launches range of jeans

The jeans come in two styles, multiple cuts and three washes and will go on sale in the UK in October
10 best over-ear headphones

Aural pleasure: 10 best over-ear headphones

Listen to your favourite tracks with this selection, offering everything from lambskin earmuffs to stainless steel
Commonwealth Games 2014: David Millar ready to serve up gold for his beloved Scotland in the end

Commonwealth Games

David Millar ready to serve up gold for his beloved Scotland in the end
UCI Mountain Bike World Cup 2014: Downhill all the way to the top for the Atherton siblings

UCI Mountain Bike World Cup

Downhill all the way to the top for the Atherton siblings
Save the tiger: The animals bred for bones on China’s tiger farms

The animals bred for bones on China’s tiger farms

The big cats kept in captivity to perform for paying audiences and then, when dead, their bodies used to fortify wine
A former custard factory, a Midlands bog and a Leeds cemetery all included in top 50 hidden spots in the UK

A former custard factory, a Midlands bog and a Leeds cemetery

Introducing the top 50 hidden spots in Britain
Ebola epidemic: Plagued by fear

Ebola epidemic: Plagued by fear

How a disease that has claimed fewer than 2,000 victims in its history has earned a place in the darkest corner of the public's imagination
Chris Pratt: From 'Parks and Recreation' to 'Guardians of the Galaxy'

From 'Parks and Recreation' to 'Guardians of the Galaxy'

He was homeless in Hawaii when he got his big break. Now the comic actor Chris Pratt is Hollywood's new favourite action star