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NovoTTF-100 'anti-cancer hat': It's the beginning of a new era in the treatment of brain tumours

 

Dr Stuart Farrimond
Sunday 15 February 2015 01:00 GMT
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The manufacturers of the NovoTTF-100A claim it can help to rid you of cancer as you pack the shopping or do the washing up
The manufacturers of the NovoTTF-100A claim it can help to rid you of cancer as you pack the shopping or do the washing up

As a doctor and a brain tumour patient myself, I know only too well this is the sort of hopeful news we desperately need to hear.

For the past decade, brain tumour research has essentially ground to a halt. Cancer researchers’ attempts to devise new chemotherapy drugs have been thwarted at every turn by the brain’s very own defence system. The so-called “blood-brain barrier” acts like a force field to keep poisons out of the brain. Researchers have found it practically impossible to develop medicines that will penetrate this biological barricade.

In 2008, I was diagnosed with a slow-growing malignant “glioma” brain tumour. It forced me to leave medicine, and although it was surgically removed, it is expected to recur as a glioblastoma. What is more exciting than the prospect of a longer life is what this represents. Not since chemotherapy was discovered some 50 years ago have we had anything new to fight cancer with. This “tumour treating fields” technology is a completely new method of medicine. Improvements to the current model are planned while the technology is set to be used on lung, pancreatic and ovarian cancer.

Cancer research conferences aren’t normally very exciting places. But when Professor Roger Stupp stood up to speak at the annual Society for Neuro-Oncology meeting in Miami last year, there was a palpable hush. He announced an experimental “anti-cancer hat” – “a new standard of care for patients suffering from glioblastoma is born”. I hope he’s wrong. I’m hoping this isn’t just a new brain cancer treatment but the beginning of a new era for how all cancers are treated.

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