Middlesbrough vs Liverpool live: Latest score and updates plus what time does it start, what TV channel is it on?

Follow live updates from the Premier League fixture at the Riverside

Loris Karius will once again be under close scrutiny after a number of mistakes for Liverpool (Getty)

Loris Karius has lost his place in Liverpool’s starting line-up ahead of Wednesday’s trip to Middlesbrough.

The under-fire goalkeeper will be replaced by Simon Mignolet after his mistakes costs points against both Bournemouth and West Ham United.

Aitor Karanka’s men are the Premier League’s lowest scorers and will hope to bounce back from Sunday’s defeat at Southampton.

Kick-off: 7.45pm

Wednesday's Premier League fixtures

• Middlesbrough vs Liverpool (7.45pm)
• Sunderland vs Chelsea (7.45pm)
• West Ham United vs Burnley (7.45pm)
• Crystal Palace vs Manchester United  (8.00pm)
• Manchester City vs Watford (8.00pm)
• Stoke City vs Southampton (8.00pm)
• Tottenham Hotspur vs Hull City (8.00pm)
• West Bromwich Albion vs Swansea City (8.00pm)

Follow live updates on the blog below...

Scroll through the scoreboard to see the latest scores from Wednesday's other matches

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It’s a big game for…

LORIS KARIUS: The German goalkeeper has struggled to keep out of the headlines of late after a number of high profile mistakes and verbal sparring with television pundits. However, here he has the chance to put that business behind him and get Liverpool back to winning ways.

Weird /best stat…

7: Middlesbrough are unbeaten in seven Premier League home matches against Liverpool since a 2-1 defeat in March 2002 (W3, D4).

Remember when…

Liverpool 2 Middlesbrough 2 (14-13 pens) Capital One Cup Third Round 2014

Both teams needed 120 minutes and 28 penalty kicks to separate them but, after Suso dispatched his decisive spot kick for Liverpool, Albert Adomah blazed his effort high and wide to send the Reds through to the fourth round.

Player to watch…

Gaston Ramirez: The Uruguayan is having an impressive season on his return to the Premier League with Boro and could cause a shaky Liverpool defence big problems at the Riverside. His cohesive partnership with Alvaro Negredo gives the home side a real threat going forward.

Past three-meetings…

LIVERPOOL 2 (Rossiter, Fernandez Saez) MIDDLESBROUGH 2 (Reach, Bamford) (14-13 pens), September 2014

MIDDLESBROUGH 2 (Alonso OG, Tuncay Sanli) LIVERPOOL 0, February 2009

LIVERPOOL 2 (Pogatetz OG, Gerrard) MIDDLESBROUGH 1 (Mido), August 2008

Form guide…

MIDDLESBROUGH: LWDLDW

LIVERPOOL: DLWWDW

Vital information…

KICK-OFF TIME: 7:45

TV: Highlights on BBC One at 10:45

[14 December 2016 18:34 · Sam Dymond]

Good evening and welcome to The Independent's live coverage of a busy night in the Premier League...

Middlesbrough v Liverpool – 7.45pm

Sunderland v Chelsea – 7.45pm

West Ham v Burnley – 7.45pm

Crystal Palace v Manchester United – 8pm

Manchester City v Watford – 8pm 

Stoke v Southampton – 8pm

Tottenham v Hull – 8pm 

West Brom v Swansea – 8pm

[14 December 2016 18:43 · Sam Dymond]

[14 December 2016 18:43 · Sam Dymond]

[14 December 2016 18:43 · Sam Dymond]

[14 December 2016 18:44 · Sam Dymond]

[14 December 2016 18:53 · Sam Dymond]

Here's the first batch of team news for tonight's games. Here's how they line up in the three 7.45pm kick-offs...

Middlesbrough v Liverpool

Middlesbrough: Valdes, Barragan, Chambers, Gibson, Fabio, Clayton, De Roon, Forshaw, Traore, Fischer, Negredo

Subs: Guzan, Nsue, Bernardo, Leadbitter, Downing, Rhodes, Nugent

Liverpool: Mignolet, Clyne, Lovren, Klavan, Milner, Henderson, Wijnaldum, Lallana, Firmino, Mane, Origi

Subs: Karius, Moreno, Lucas, Stewart, Alexander, Ejaria, Woodburn

Referee: Jonathan Moss

Sunderland v Chelsea

Sunderland: Pickford, Jones, Van Aanholt, Djilobodji, Kone, O’Shea, Denayer, Kirchhoff, Januzaj, Borini, Defoe

Subs: Mannone, Love, Asoro, Larsson, Khazri, Maja, Honeyman

Chelsea: Courtois, Azpilicueta, Luiz, Cahill, Moses, Kante, Fabregas, Alonso, Willian, Costa, Pedro

Subs: Begovic, Ivanovic, Zouma, Chalobah, Matic, Loftus-Cheek, Batshuayi

Referee: Neil Swarbrick

West Ham v Burnley

West Ham: Randolph, Antonio, Reid, Ogbonna, Cresswell, Kouyate, Obiang, Noble, Lanzini, Payet, Carroll

Subs: Adrian, Nordtveit, Ayew, Fletcher, Fernandes, Quina, Browne

Burnley: Heaton, Ward, Mee, Keane, Lowton, Arfield, Marney, Hendrick, Boyd, Vokes, Gray

Subs: Robinson, Flanagan, Barnes, Kightly, Bamford, Defour, Tarkowski

Referee: Bobby Madley

[14 December 2016 19:00 · Sam Dymond]

The key news of notes from those matches are...

...no Eden Hazard...

...no Lorus Karius...

...but Andy Carroll starts for West Ham.

[14 December 2016 19:15 · Sam Dymond]

And more team news...

Crystal Palace v Manchester United

Crystal Palace: Hennessey, Ward, Dann, Delaney, Kelly, McArthur, Flamini, Cabaye, Lee, Zaha, Benteke

Subs: Speroni, Fryers, Ledley, Husin, Townsend, Wan-Bissaka, Campbell

Manchester United: De Gea, Bailly, Jones, Rojo, Blind, Herrera, Carrick, Pogba, Rooney, Mata, Ibrahimovic

Subs: Romero, Darmian, Fellaini, Lingard, Schweinsteiger, Young, Rashford

Referee: Craig Pawson

Manchester City v Watford

Manchester City: Bravo, Zabaleta, Otamendi, Kolarov, Clichy, Gundogan, Toure, Sterling, De Bruyne, Silva, Nolito

Subs: Caballero, Sagna, Fernando, Navas, Sane, Stones, Iheanacho

Watford: Gomes, Janmaat, Prodl, Britos, Holebas, Pereyra, Guedioura, Capoue, Amrabat, Ighalo, Sinclair

Subs: Pantilimon, Kaboul, Kabasele, Zuniga, Watson, Success, Deeney

Referee: Kevin Friend

Stoke City v Southampton

Stoke: Grant, Johnson, Shawcross, Martins Indi, Pieters, Whelan, Adam, Shaqiri, Allen, Arnautovic, Walters

Subs: Given, Muniesa, Bony, Diouf, Imbula, Crouch, Bojan

Southampton: Forster, Martina, Van Dijk, Fonte, Bertrand, Romeu, Ward-Prowse, Davis, Redmond, Boufal, Long

Subs: Taylor, Yoshida, Clasie, Rodriguez, Tadic, Hojbjerg, McQueen

Referee: Anthony Taylor

Tottenham v Hull

Tottenham: Lloris, Walker, Alderweireld, Vertonghen, Rose, Dier, Wanyama, Sissoko, Eriksen, Alli, Kane

Subs: Vorm, Trippier, Davies, Winks, Onomah, Nkoudou, Son

Hull: Marshall, Maguire, Dawson, Davies, Elmohamady, Livermore, Huddlestone, Clucas, Robertson, Snodgrass, Diomande

Subs: Jakupovic, Meyler, Maloney, Weir, Henriksen, Mason, Bowen

Referee: Andre Marriner

West Brom v Swansea

West Brom: Foster, Nyom, McAuley, Olsson, Brunt, Yacob, Fletcher, Chadli, Morrison, Phillips, Rondon

Subs: Palmer; Robson-Kanu, Gardner, McClean, Galloway, Harper, Leko

Swansea: Fabianski, Rangel, Mawson, Amat, Taylor, Fulton, Britton, Sigurdsson, Routledge, Montero, Llorente

Subs: Nordfeldt, Naughton, Van der Hoorn, Cork, Fer, Barrow, Borja

Referee: Michael Oliver

[14 December 2016 19:19 · Sam Dymond]

A man for the big occasion?

[14 December 2016 19:28 · Sam Dymond]

Wayne Rooney starts for Manchester United at Crystal Palace this evening.

He needs one goal to equal Bobby Charlton's club record and the great man is in attendance at Selhurst Park to see if he can manage it.