Arts and Entertainment Jared Leto in 'Dallas Buyers Club'

When will TV and film start opening the door to transgender actors, asks Paris Lees

Backbench Conservatives MPs have been criticised for supporting a proposed ban on HIV positive immigrants entering Britain

Ban on HIV positive immigrants entering the UK proposed for Immigration Bill by Tory MPs

HIV and AIDs campaigners have called the amendment "draconian"

Men about town: Frankie Alvarez, Murray Bartlett and Jonathon Groff in ‘Looking’

Looking: The first drama about gay men since Queer as Folk

Show has given Russell Tovey his ideal role, he tells Gerard Gilbert

With insights like these, Gerald Howarth must be a shoo-in for the Most Cerebral Backbencher award

This veteran intellectual giant of the frothing right has been a delight since first being elected in 1983

Matthew McConaughey committed to a strict diet ahead of playing Ron Woodroof in Dallas Buyers Club

Matthew McConaughey ate spoonful of pudding a day to lose weight for Dallas Buyers Club

The Oscar-nominated actor lost 47lbs for his role as an AIDS patient

Matthew McConaughey delivers impassioned, ecstatic speech at SAG Awards

Actor won award for Dallas Buyers Club

Cate Blanchett at the 20th annual Screen Actors Guild Awards, where she picked up the award for Best Female Actor in a Leading Role

Screen Actors Guild Awards 2014: Cate Blanchett, Matthew McConaughey and Breaking Bad among winners

American Hustle picked up the award for Best Cast in a Motion Picture

Amy Adams, Bradley Cooper, Jeremy Renner, Christian Bale and Jennifer Lawrence in American Hustle

Screen Actors Guild Awards 2014: Winners list in full

Dallas Buyers Club and Breaking Bad took home two awards each

Chiwetel Ejiofor has been nominated for an Oscar for his role as Solomon Northup in 12 Years a Slave

Oscars 2014: Chiwetel Ejiofor and Leonardo DiCaprio nominated for Best Actor

Michael Fassbender and Bradley Cooper are up for Best Supporting Actor

Nigeria's anti-gay laws: Homosexuals rounded up and beaten, rights groups claim

Same Sex Marriage Prohibition Act was passed on Monday

Christmas album reviews: Leona Lewis, Erasure, Bright Eyes, Mary J Blige, Richard Durrant

Leona Lewis: "Christmas, with Love" (Syco / RCA)

Elephant Appeal: The continent I fell in love with may be changed forever

My two sons may never experience Africa and its wildlife like I had the chance to

Sending homosexual delegates to Sochi doesn't begin to address Russia's gay rights crisis

Barack Obama gravely overlooks the unfolding HIV epidemic in Russia

Electron microscope image of the Aids virus

HIV patients ‘cured’ of Aids suffer relapse

News 'disappointing but scientifically significant' as it shows that Aids virus persists even when sensitive blood tests fail to detect it

Prime Minister David Cameron speaks at the G8 Dementia Summit

G8 Dementia Summit: Leading nations pledge 'significant increase' in amount spent on research

The number of global sufferers is expected to rise to 135m by 2050

The Care Quality Commission (CQC) has announced a national review of dementia care

G8 Dementia Summit: PM pledges to double funding for research by 2025

While GlaxoSmithKline announces £200m of investment to set up a 'centre of excellence' that will turn breakthroughs in the lab into effective drugs

Life and Style
A monstrous idea? Body transplants might no longer be science fiction
Science An Italian neurosurgeon believes so - and it's not quite as implausible as it sounds, says Steve Connor
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Demba Ba (right) celebrates after Besiktas win on penalties
footballThere was no happy return to the Ataturk Stadium, where the Reds famously won Champions League
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Day In a Page

Independent Travel
Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
Burgundy, the River Rhone & Provence
Prague, Budapest and Vienna
Lake Garda
3.	Provence 6 nights B&B by train from £599pp
Prices correct as of 20 February 2015
HIV pill: Scientists hail discovery of 'game-changer' that cuts the risk of infection among gay men by 86%

Scientists hail daily pill that protects against HIV infection

Breakthrough in battle against global scourge – but will the NHS pay for it?
How we must adjust our lifestyles to nature: Welcome to the 'Anthropocene', the human epoch

Time to play God

Welcome to the 'Anthropocene', the human epoch where we may need to redefine nature itself
MacGyver returns, but with a difference: Handyman hero of classic 1980s TV series to be recast as a woman

MacGyver returns, but with a difference

Handyman hero of classic 1980s TV series to be recast as a woman
Tunnel renaissance: Why cities are hiding roads down in the ground

Tunnel renaissance

Why cities are hiding roads underground
'Backstreet Boys - Show 'Em What You're Made Of': An affectionate look at five middle-aged men

Boys to men

The Backstreet Boys might be middle-aged, married and have dodgy knees, but a heartfelt documentary reveals they’re not going gently into pop’s good night
Crufts 2015: Should foreign dogs be allowed to compete?

Crufts 2015

Should foreign dogs be allowed to compete?
10 best projectors

How to make your home cinema more cinematic: 10 best projectors

Want to recreate the big-screen experience in your sitting room? IndyBest sizes up gadgets to form your film-watching
Manchester City 1 Barcelona 2 player ratings: Luis Suarez? Lionel Messi? Joe Hart? Who was the star man?

Manchester City vs Barcelona player ratings

Luis Suarez? Lionel Messi? Joe Hart? Who was the star man at the Etihad?
Arsenal vs Monaco: Monaco - the making of Gunners' manager Arsene Wenger

Monaco: the making of Wenger

Jack Pitt-Brooke speaks to former players and learns the Frenchman’s man-management has always been one of his best skills
Cricket World Cup 2015: Chris Gayle - the West Indies' enigma lives up to his reputation

Chris Gayle: The West Indies' enigma

Some said the game's eternal rebel was washed up. As ever, he proved he writes the scripts by producing a blistering World Cup innings
In Ukraine a dark world of hybrid warfare and murky loyalties prevails

In Ukraine a dark world of hybrid warfare

This war in the shadows has been going on since the fall of Mr Yanukovych
'Birdman' and 'Bullets Over Broadway': Homage or plagiarism?

Homage or plagiarism?

'Birdman' shares much DNA with Woody Allen's 'Bullets Over Broadway'
Broadchurch ends as damp squib not even David Tennant can revive

A damp squib not even David Tennant can revive

Broadchurch, Series 2 finale, review
A Koi carp breeding pond, wall-mounted iPads and a bathroom with a 'wellness' shower: inside the mansion of Germany's 'Bishop of Bling'

Inside the mansion of Germany's 'Bishop of Bling'

A Koi carp breeding pond, wall-mounted iPads and a bathroom with a 'wellness' shower