Breakthrough could lead to cure for chronic liver disease

Medical scientists have taken an important step towards understanding how the diseased liver can repair itself in a breakthrough that could eventually lead to the development of new treatments for chronic liver illnesses, which at present can only be cured by organ transplants.

Winning ways: the chef Wolfgang Puck shows the foods on offer at the Oscars

Served with ceremony: The culinary trends at this year's awards parties

Tim Walker gets to sample delicacies including edible gold flakes and mojito mousse

Doctors warn on alcohol deaths

More than 200,000 people could die early from alcohol over the next 20 years, leading doctors have warned.

James Moore: Bolland's bacon saved as M&S counts the cost of Christmas flop

If Marks & Spencer's Christmas figures are anything to go by, the pixie dust Marc Bolland sprinkled on Morrisons to make it fly has been in short supply. Yesterday's trading statement was no Christmas cracker and the shares would have taken a beating had it not been for a bravura performance by the retailer's food halls. That saved Mr Bolland's bacon, at least for now.

James Moore: Food saves Bolland's bacon as M&S counts the cost of a Christmas flop

Outlook If Marks & Spencer's Christmas figures are anything to go by, the pixie dust Marc Bolland sprinkled on Morrisons to make it fly has been in short supply. Yesterday's trading statement was no Christmas cracker and the shares would have taken a beating had it not been for a bravura performance from the retailer's food offering. That saved Mr Bolland's bacon. At least for now.

The Government is under growing pressure to rethink its imminent alcohol strategy and its guidelines for sensible drinking

Alcohol: keep a clear head

A new government report on drinking alcohol aims to give us easy to understand, no-nonsense advice. But are we ready to listen?

The Commons' Science and Technology Committee believed abstaining from alcohol at least twice a week would help people's health

Drinkers should have two alcohol-free days a week

Drinkers should give themselves two alcohol-free days a week, a committee of MPs said today.

Roberto Bolaño: 'The Spanish language is my homeland'

The Third Reich, By Roberto Bolaño (trs Natasha Wimmer)

A newly translated novel, written in the 1980s, reveals the preoccupations of a Chilean master as well has his trademark sarcasm and dark humour

Joe Tizzard clears the water jump on Cue Card at Newbury

Cut in distance leaves Cue Card holding all the aces

The last day of an old year is as good a time as any to look to the future. Racing is unusual among sports that callow young beginners regularly compete on the same programmes as seasoned veterans, rather than being tucked away at junior meets or youth squad matches. And their presence in the public eye from the start makes the tracing of real talent all the more absorbing, though it's spotting not necessarily easier.

January liver detoxes are 'futile' say hepatologist

Going on a New Year detox to cleanse your liver is "medically futile", health experts warned yesterday.

Twins born with one body and two heads

Hospital officials in northern Brazil say a woman have given birth to conjoined twin boys with one body and two heads.

Alcohol diseases double in 7 years

The Health Minister Andrew Lansley was forced to defend his controversial "hands off" approach to public health yesterday as new figures revealed hospital admissions for alcohol-related diseases have doubled in the past seven years.

Right-to-die suicide letter angry at MP's 'cowardice'

A British woman who travelled to Switzerland to die has condemned the "cowardice of politicians" which forced her to spend her last hours away from home.

Pledge over drink advertising aimed at young

Ministers charged with delivering the Olympic Games have vowed to protect young people from binge drinking.

Ali and Frazier fought some of the greatest heavy-weight bouts of all time

Muhammad Ali praying for Joe Frazier

Former world heavyweight champion Muhammad Ali today said he was praying for Joe Frazier following the news of his great rival's battle against cancer.

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Pompeii, Capri & the Bay of Naples
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Lake Garda
Minoan Crete and Santorini
Prices correct as of 15 May 2015
A nap a day could save your life - and here's why

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A midday nap is 'associated with reduced blood pressure'
If men are so obsessed by sex, why do they clam up when confronted with the grisly realities?

If men are so obsessed by sex...

...why do they clam up when confronted with the grisly realities?
The comedy titans of Avalon on their attempt to save BBC3

Jon Thoday and Richard Allen-Turner

The comedy titans of Avalon on their attempt to save BBC3
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Conservatives plot a motoring revolution

Draft report reveals biggest reform to regulations since driving test introduced in 1935
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Long before the West rose to power, Asian pathways were connecting peoples and places
House of Lords: Outcry as donors, fixers and MPs caught up in expenses scandal are ennobled

The honours that shame Britain

Outcry as donors, fixers and MPs caught up in expenses scandal are ennobled
When it comes to street harassment, we need to talk about race

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Why are black men living the stereotypes and why are we letting them get away with it?
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International Tap Festival comes to the UK

Forget Fred Astaire and Ginger Rogers - this dancing is improvised, spontaneous and rhythmic
War with Isis: Is Turkey's buffer zone in Syria a matter of self-defence – or just anti-Kurd?

Turkey's buffer zone in Syria: self-defence – or just anti-Kurd?

Ankara accused of exacerbating racial division by allowing Turkmen minority to cross the border
Doris Lessing: Acclaimed novelist was kept under MI5 observation for 18 years, newly released papers show

'A subversive brothel keeper and Communist'

Acclaimed novelist Doris Lessing was kept under MI5 observation for 18 years, newly released papers show
Big Blue Live: BBC's Springwatch offshoot swaps back gardens for California's Monterey Bay

BBC heads to the Californian coast

The Big Blue Live crew is preparing for the first of three episodes on Sunday night, filming from boats, planes and an aquarium studio
Austin Bidwell: The Victorian fraudster who shook the Bank of England with the most daring forgery the world had known

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Conman Austin Bidwell. was a heartless cad who carried out the most daring forgery the world had known
Car hacking scandal: Security designed to stop thieves hot-wiring almost every modern motor has been cracked

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Security designed to stop thieves hot-wiring almost every modern motor has been cracked
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