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Breakthrough could lead to cure for chronic liver disease

Medical scientists have taken an important step towards understanding how the diseased liver can repair itself in a breakthrough that could eventually lead to the development of new treatments for chronic liver illnesses, which at present can only be cured by organ transplants.

Winning ways: the chef Wolfgang Puck shows the foods on offer at the Oscars

Served with ceremony: The culinary trends at this year's awards parties

Tim Walker gets to sample delicacies including edible gold flakes and mojito mousse

Doctors warn on alcohol deaths

More than 200,000 people could die early from alcohol over the next 20 years, leading doctors have warned.

James Moore: Bolland's bacon saved as M&S counts the cost of Christmas flop

If Marks & Spencer's Christmas figures are anything to go by, the pixie dust Marc Bolland sprinkled on Morrisons to make it fly has been in short supply. Yesterday's trading statement was no Christmas cracker and the shares would have taken a beating had it not been for a bravura performance by the retailer's food halls. That saved Mr Bolland's bacon, at least for now.

James Moore: Food saves Bolland's bacon as M&S counts the cost of a Christmas flop

Outlook If Marks & Spencer's Christmas figures are anything to go by, the pixie dust Marc Bolland sprinkled on Morrisons to make it fly has been in short supply. Yesterday's trading statement was no Christmas cracker and the shares would have taken a beating had it not been for a bravura performance from the retailer's food offering. That saved Mr Bolland's bacon. At least for now.

The Government is under growing pressure to rethink its imminent alcohol strategy and its guidelines for sensible drinking

Alcohol: keep a clear head

A new government report on drinking alcohol aims to give us easy to understand, no-nonsense advice. But are we ready to listen?

The Commons' Science and Technology Committee believed abstaining from alcohol at least twice a week would help people's health

Drinkers should have two alcohol-free days a week

Drinkers should give themselves two alcohol-free days a week, a committee of MPs said today.

Roberto Bolaño: 'The Spanish language is my homeland'

The Third Reich, By Roberto Bolaño (trs Natasha Wimmer)

A newly translated novel, written in the 1980s, reveals the preoccupations of a Chilean master as well has his trademark sarcasm and dark humour

January liver detoxes are 'futile' say hepatologist

Going on a New Year detox to cleanse your liver is "medically futile", health experts warned yesterday.

Joe Tizzard clears the water jump on Cue Card at Newbury

Cut in distance leaves Cue Card holding all the aces

The last day of an old year is as good a time as any to look to the future. Racing is unusual among sports that callow young beginners regularly compete on the same programmes as seasoned veterans, rather than being tucked away at junior meets or youth squad matches. And their presence in the public eye from the start makes the tracing of real talent all the more absorbing, though it's spotting not necessarily easier.

Twins born with one body and two heads

Hospital officials in northern Brazil say a woman have given birth to conjoined twin boys with one body and two heads.

Alcohol diseases double in 7 years

The Health Minister Andrew Lansley was forced to defend his controversial "hands off" approach to public health yesterday as new figures revealed hospital admissions for alcohol-related diseases have doubled in the past seven years.

Right-to-die suicide letter angry at MP's 'cowardice'

A British woman who travelled to Switzerland to die has condemned the "cowardice of politicians" which forced her to spend her last hours away from home.

Pledge over drink advertising aimed at young

Ministers charged with delivering the Olympic Games have vowed to protect young people from binge drinking.

Ali and Frazier fought some of the greatest heavy-weight bouts of all time

Muhammad Ali praying for Joe Frazier

Former world heavyweight champion Muhammad Ali today said he was praying for Joe Frazier following the news of his great rival's battle against cancer.

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Mystery of the Ground Zero wedding photo

A shot in the dark

Mystery of the wedding photo from Ground Zero
His life, the universe and everything

His life, the universe and everything

New biography sheds light on comic genius of Douglas Adams
Save us from small screen superheroes

Save us from small screen superheroes

Shows like Agents of S.H.I.E.L.D are little more than marketing tools
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Reach for the skies

From pools to football pitches, rooftop living is looking up
These are the 12 best hotel spas in the UK

12 best hotel spas in the UK

Some hotels go all out on facilities; others stand out for the sheer quality of treatments
These Iranian-controlled Shia militias used to specialise in killing American soldiers. Now they are fighting Isis, backed up by US airstrikes

Widespread fear of Isis is producing strange bedfellows

Iranian-controlled Shia militias that used to kill American soldiers are now fighting Isis, helped by US airstrikes
Topshop goes part Athena poster, part last spring Prada

Topshop goes part Athena poster, part last spring Prada

Shoppers don't come to Topshop for the unique
How to make a Lego masterpiece

How to make a Lego masterpiece

Toy breaks out of the nursery and heads for the gallery
Meet the ‘Endies’ – city dwellers who are too poor to have fun

Meet the ‘Endies’ – city dwellers who are too poor to have fun

Urbanites are cursed with an acronym pointing to Employed but No Disposable Income or Savings
Paisley’s decision to make peace with IRA enemies might remind the Arabs of Sadat

Ian Paisley’s decision to make peace with his IRA enemies

His Save Ulster from Sodomy campaign would surely have been supported by many a Sunni imam
'She was a singer, a superstar, an addict, but to me, her mother, she is simply Amy'

'She was a singer, a superstar, an addict, but to me, her mother, she is simply Amy'

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Is this the role to win Cumberbatch an Oscar?

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England and Roy Hodgson take a joint step towards redemption in Basel

England and Hodgson take a joint step towards redemption

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Relatives fight over Vivian Maier’s rare photos

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‘Fashion has to be fun. It’s a big business, not a cure for cancer’

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