Breakthrough could lead to cure for chronic liver disease

Medical scientists have taken an important step towards understanding how the diseased liver can repair itself in a breakthrough that could eventually lead to the development of new treatments for chronic liver illnesses, which at present can only be cured by organ transplants.

Winning ways: the chef Wolfgang Puck shows the foods on offer at the Oscars

Served with ceremony: The culinary trends at this year's awards parties

Tim Walker gets to sample delicacies including edible gold flakes and mojito mousse

Doctors warn on alcohol deaths

More than 200,000 people could die early from alcohol over the next 20 years, leading doctors have warned.

James Moore: Bolland's bacon saved as M&S counts the cost of Christmas flop

If Marks & Spencer's Christmas figures are anything to go by, the pixie dust Marc Bolland sprinkled on Morrisons to make it fly has been in short supply. Yesterday's trading statement was no Christmas cracker and the shares would have taken a beating had it not been for a bravura performance by the retailer's food halls. That saved Mr Bolland's bacon, at least for now.

James Moore: Food saves Bolland's bacon as M&S counts the cost of a Christmas flop

Outlook If Marks & Spencer's Christmas figures are anything to go by, the pixie dust Marc Bolland sprinkled on Morrisons to make it fly has been in short supply. Yesterday's trading statement was no Christmas cracker and the shares would have taken a beating had it not been for a bravura performance from the retailer's food offering. That saved Mr Bolland's bacon. At least for now.

The Government is under growing pressure to rethink its imminent alcohol strategy and its guidelines for sensible drinking

Alcohol: keep a clear head

A new government report on drinking alcohol aims to give us easy to understand, no-nonsense advice. But are we ready to listen?

The Commons' Science and Technology Committee believed abstaining from alcohol at least twice a week would help people's health

Drinkers should have two alcohol-free days a week

Drinkers should give themselves two alcohol-free days a week, a committee of MPs said today.

Roberto Bolaño: 'The Spanish language is my homeland'

The Third Reich, By Roberto Bolaño (trs Natasha Wimmer)

A newly translated novel, written in the 1980s, reveals the preoccupations of a Chilean master as well has his trademark sarcasm and dark humour

January liver detoxes are 'futile' say hepatologist

Going on a New Year detox to cleanse your liver is "medically futile", health experts warned yesterday.

Joe Tizzard clears the water jump on Cue Card at Newbury

Cut in distance leaves Cue Card holding all the aces

The last day of an old year is as good a time as any to look to the future. Racing is unusual among sports that callow young beginners regularly compete on the same programmes as seasoned veterans, rather than being tucked away at junior meets or youth squad matches. And their presence in the public eye from the start makes the tracing of real talent all the more absorbing, though it's spotting not necessarily easier.

Twins born with one body and two heads

Hospital officials in northern Brazil say a woman have given birth to conjoined twin boys with one body and two heads.

Alcohol diseases double in 7 years

The Health Minister Andrew Lansley was forced to defend his controversial "hands off" approach to public health yesterday as new figures revealed hospital admissions for alcohol-related diseases have doubled in the past seven years.

Right-to-die suicide letter angry at MP's 'cowardice'

A British woman who travelled to Switzerland to die has condemned the "cowardice of politicians" which forced her to spend her last hours away from home.

Pledge over drink advertising aimed at young

Ministers charged with delivering the Olympic Games have vowed to protect young people from binge drinking.

Ali and Frazier fought some of the greatest heavy-weight bouts of all time

Muhammad Ali praying for Joe Frazier

Former world heavyweight champion Muhammad Ali today said he was praying for Joe Frazier following the news of his great rival's battle against cancer.

Sport
England's women celebrate after their 3rd place play-off win against Germany
Women's World CupFara Williams converts penalty to secure victory and bronze medals
Arts and Entertainment
Ricardo by Edward Sutcliffe, 2014
artPortraits of LA cricketers from notorious suburb go on display
News
newsHillary Clinton comments on viral Humans of New York photo of gay teenager
Arts and Entertainment
The gang rape scene in the Royal Opera’s production of Gioachino Rossini’s Guillaume Tell has caused huge controversy
music
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Novak Djokovic has been attending the Buddhapadipa Temple for quiet contemplation for several years
wimbledonBuddhapadipa Temple is regular refuge for the world No 1
Life and Style
Kissing
life
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wimbledonScot will face Ivo Karlovic next
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i100
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Lewis Hamilton takes pole on front of his home fans
f1
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British singer 'Lonelady' performing in Bourges (Getty)
musicMONEY, Lonelady, Dr Meaker... Which ones have you heard of?
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Independent Travel
Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
Burgundy, the River Rhone & Provence
Prague, Budapest and Vienna
Lake Garda
Minoan Crete and Santorini
Prices correct as of 15 May 2015
The Greek referendum exposes a gaping hole at the heart of the European Union – its distinct lack of any genuine popular legitimacy

Gaping hole at the heart of the European Union

Treatment of Greece has shown up a lack of genuine legitimacy
Number of young homeless in Britain 'more than three times the official figures'

'Everything changed when I went to the hostel'

Number of young homeless people in Britain is 'more than three times the official figures'
Compton Cricket Club

Compton Cricket Club

Portraits of LA cricketers from notorious suburb to be displayed in London
London now the global money-laundering centre for the drug trade, says crime expert

Wlecome to London, drug money-laundering centre for the world

'Mexico is its heart and London is its head'
The Buddhist temple minutes from Centre Court that helps a winner keep on winning

The Buddhist temple minutes from Centre Court

It helps a winner keep on winning
Is this the future of flying: battery-powered planes made of plastic, and without flight decks?

Is this the future of flying?

Battery-powered planes made of plastic, and without flight decks
Isis are barbarians – but the Caliphate is a dream at the heart of all Muslim traditions

Isis are barbarians

but the Caliphate is an ancient Muslim ideal
The Brink's-Mat curse strikes again: three tons of stolen gold that brought only grief

Curse of Brink's Mat strikes again

Death of John 'Goldfinger' Palmer the latest killing related to 1983 heist
Greece debt crisis: 'The ministers talk to us about miracles' – why Greeks are cynical ahead of the bailout referendum

'The ministers talk to us about miracles'

Why Greeks are cynical ahead of the bailout referendum
Call of the wild: How science is learning to decode the way animals communicate

Call of the wild

How science is learning to decode the way animals communicate
Greece debt crisis: What happened to democracy when it’s a case of 'Vote Yes or else'?

'The economic collapse has happened. What is at risk now is democracy...'

If it doesn’t work in Europe, how is it supposed to work in India or the Middle East, asks Robert Fisk
The science of swearing: What lies behind the use of four-letter words?

The science of swearing

What lies behind the use of four-letter words?
The Real Stories of Migrant Britain: Clive fled from Zimbabwe - now it won't have him back

The Real Stories of Migrant Britain

Clive fled from Zimbabwe - now it won’t have him back
Africa on the menu: Three foodie friends want to popularise dishes from the continent

Africa on the menu

Three foodie friends want to popularise dishes from the hot new continent
Donna Karan is stepping down after 30 years - so who will fill the DKNY creator's boots?

Who will fill Donna Karan's boots?

The designer is stepping down as Chief Designer of DKNY after 30 years. Alexander Fury looks back at the career of 'America's Chanel'