Parents put their Faith and Hope in hands of surgeons

Operation being carried out to separate conjoined twin girls

Liver, By Will Self

Talking about degeneration in a city of bile

The pill that lets dieters eat what they like

A pill which may "lock in" the benefits of dieting, allowing dieters to return to normal eating without putting on weight, has been discovered by scientists.

Jeremy Laurance: Good news, but think twice before popping pills

They are the biggest-selling drugs in the world – and with reason. In the UK, cardiovascular disease causes more than one in three deaths – 120,000 mortalities a year. Statins have the capacity to cut that toll by a third. Hence their billing as the "miracle drugs" of the 21st century.

'I was diagnosed with cancer and found out I was pregnant on the same day'

For Audrey Eade, being pregnant was a bittersweet experience. Sweet, because she enjoyed the feeling of having the baby growing inside her; bitter, because of her conviction that there would be no happy ending, "no Carl, me and the baby" afterwards.

Toxic shower curtain warning

American scientists are warning that the humble plastic shower curtain is responsible for releasing more than 100 toxic chemicals into homes, including some suspected of causing cancer or having gender-bending effects.

FBI helped Japanese gangster to have life-saving transplant in US

A Japanese gangster, known as the "John Gotti of Japan", was flown to the United States for a life-saving liver transplant with the connivance of the FBI.

Police shot barrister at least five times, inquest hears

Mark Saunders was shot at least five times by police to end the siege at his Chelsea home, an inquest heard.

MP calls for alcohol ad ban at sports events

A ban on alcohol advertising at sporting events is being demanded by a Labour MP in an attempt to tackle binge drinking among young people.

Tindall set to put liver on line in cup crunch

Mike Tindall's serious liver problems, the direct result of on-field events during the Six Nations Championship match between England and Wales at Twickenham rather than off-field ones after it, have prevented him playing rugby for two months now. There is, however, a chance – quite a good chance, according to his head coach – that he will be back in the Gloucester mix for this weekend's Heineken Cup quarter-final against Munster at Kingsholm. "We lose something when we play without Mike, so if we can get him involved without too much risk, we'll do it," said Dean Ryan yesterday.

Drug lowers cholesterol and fights hepatitis C

A drug that can lower cholesterol levels and prevent the liver from being attacked by the hepatitis C virus has come a step closer following a successful trial on laboratory animals.

Bruised liver likely to end Tindall's season

Just as Brian Ashton, the England head coach, was beginning his analysis of one of the more jaw-dropping system failures in recent red-rose history – in short, how his side managed to present Wales with a first Twickenham victory in two decades after laying the foundations for what should have been a 30-point stroll – he was presented with a problem every bit as big and twice as urgent.

Britain's transplant crisis: Poor lifestyle fuels big rise in waiting lists

Binge drinking is blamed for a 76 per cent increase in 10 years in those needing a new liver, while the demand for kidney replacements is up 55 per cent. This week, a 14-point plan will try to tackle the donor shortage. By Nina Lakhani

Athletics: Pavey adds to UK record collection

Briton follows up Bekele's world indoor best to earn the approval of watching old rival Radcliffe

Vigil honours the healing qualities of Afghanistan's al-Qa'ida cemetery

There are new graves at the al-Qa'ida cemetery, the shrine to the "martyrs" who had died fighting in the US-led invasion four years ago. The fresh mounds of earth were dug for those killed in the ferocious fighting of the recent months as war returned to Afghanistan.

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Day In a Page

Independent Travel
Burgundy, the River Rhone & Provence – Five-star MS Swiss Corona 7 nights from £999pp
Lake Como St Moritz & the Bernina Express 7 nights from £809pp
Vietnam
Lake Maggiore, Orta & the Matterhorn 7 nights from £939pp
South Africa
Spain
Prices correct as of 19 December 2014
A timely reminder of the bloody anniversary we all forgot

A timely reminder of the bloody anniversary we all forgot

Who remembers that this week we enter the 150th anniversary year of the end of the American Civil War, asks Robert Fisk
Homeless Veterans appeal: Former soldiers pay their respects to a friend who also served

Homeless Veterans appeal

Former soldiers pay their respects to a friend who also served
Downfall of Dustin 'Screech' Diamond, the 'Saved By The Bell' star charged with bar stabbing

Scarred by the bell

The downfall of the TV star charged with bar stabbing
Why 2014 was a year of technological let-downs

Why 2014 was a year of technological let-downs

Security breaches and overhyped start-ups dominated a year in which very little changed (save the size of your phone)
Cuba's golf revolution: But will the revolutionary nation take 'bourgeois' game to its heart?

Will revolutionary Cuba take 'bourgeois' golf to its heart?

Fidel Castro ridiculed the game – but now investment in leisure resort projects is welcome
The Locked Room Mysteries: As a new collection of the genre’s best is published, its editor Otto Penzler explains the rules of engagement

The Locked Room Mysteries

As a new collection of the genre’s best is published, its editor explains the rules of engagement
Amy Adams on playing painter Margaret Keane in Tim Burton's Big Eyes

How I made myself Keane

Amy Adams hadn’t wanted to take the role of artist Margaret Keane, because she’d had enough of playing victims. But then she had a daughter, and saw the painter in a new light
Ed Richards: Parting view of Ofcom chief. . . we hate jokes on the disabled

Parting view of Ofcom chief... we hate jokes on the disabled

Bad language once got TV viewers irate, inciting calls to broadcasting switchboards. But now there is a worse offender, says retiring head of the media watchdog, Ed Richards
A look back at fashion in 2014: Wear in review

Wear in review

A look back at fashion in 2014
Ian Herbert: My 10 hopes for sport in 2015. Might just one of them happen?

Ian Herbert: My 10 hopes for sport in 2015

Might just one of them happen?
War with Isis: The West needs more than a White Knight

The West needs more than a White Knight

Despite billions spent on weapons, the US has not been able to counter Isis's gruesome tactics, says Patrick Cockburn
Return to Helmand: Private Davey Graham recalls the day he was shot by the Taliban

'The day I was shot by the Taliban'

Private Davey Graham was shot five times during an ambush in 2007 - it was the first, controversial photograph to show the dangers our soldiers faced in Helmand province
Revealed: the best and worst airlines for delays

Revealed: the best and worst airlines for delays

Many flyers are failing to claim compensation to which they are entitled, a new survey has found
The stories that defined 2014: From the Scottish independence referendum to the Ice Bucket Challenge, our writers voice their opinions

The stories that defined 2014

From the Scottish independence referendum to the Ice Bucket Challenge, our writers voice their opinions
Stoke-on-Trent becomes first British city to be classified as 'disaster resilient' by the United Nations

Disaster looming? Now you know where to head...

Which British city has become the first to be awarded special 'resilience' status by the UN?