Parents put their Faith and Hope in hands of surgeons

Operation being carried out to separate conjoined twin girls

Liver, By Will Self

Talking about degeneration in a city of bile

The pill that lets dieters eat what they like

A pill which may "lock in" the benefits of dieting, allowing dieters to return to normal eating without putting on weight, has been discovered by scientists.

Jeremy Laurance: Good news, but think twice before popping pills

They are the biggest-selling drugs in the world – and with reason. In the UK, cardiovascular disease causes more than one in three deaths – 120,000 mortalities a year. Statins have the capacity to cut that toll by a third. Hence their billing as the "miracle drugs" of the 21st century.

'I was diagnosed with cancer and found out I was pregnant on the same day'

For Audrey Eade, being pregnant was a bittersweet experience. Sweet, because she enjoyed the feeling of having the baby growing inside her; bitter, because of her conviction that there would be no happy ending, "no Carl, me and the baby" afterwards.

Toxic shower curtain warning

American scientists are warning that the humble plastic shower curtain is responsible for releasing more than 100 toxic chemicals into homes, including some suspected of causing cancer or having gender-bending effects.

FBI helped Japanese gangster to have life-saving transplant in US

A Japanese gangster, known as the "John Gotti of Japan", was flown to the United States for a life-saving liver transplant with the connivance of the FBI.

Police shot barrister at least five times, inquest hears

Mark Saunders was shot at least five times by police to end the siege at his Chelsea home, an inquest heard.

MP calls for alcohol ad ban at sports events

A ban on alcohol advertising at sporting events is being demanded by a Labour MP in an attempt to tackle binge drinking among young people.

Tindall set to put liver on line in cup crunch

Mike Tindall's serious liver problems, the direct result of on-field events during the Six Nations Championship match between England and Wales at Twickenham rather than off-field ones after it, have prevented him playing rugby for two months now. There is, however, a chance – quite a good chance, according to his head coach – that he will be back in the Gloucester mix for this weekend's Heineken Cup quarter-final against Munster at Kingsholm. "We lose something when we play without Mike, so if we can get him involved without too much risk, we'll do it," said Dean Ryan yesterday.

Drug lowers cholesterol and fights hepatitis C

A drug that can lower cholesterol levels and prevent the liver from being attacked by the hepatitis C virus has come a step closer following a successful trial on laboratory animals.

Bruised liver likely to end Tindall's season

Just as Brian Ashton, the England head coach, was beginning his analysis of one of the more jaw-dropping system failures in recent red-rose history – in short, how his side managed to present Wales with a first Twickenham victory in two decades after laying the foundations for what should have been a 30-point stroll – he was presented with a problem every bit as big and twice as urgent.

Britain's transplant crisis: Poor lifestyle fuels big rise in waiting lists

Binge drinking is blamed for a 76 per cent increase in 10 years in those needing a new liver, while the demand for kidney replacements is up 55 per cent. This week, a 14-point plan will try to tackle the donor shortage. By Nina Lakhani

Athletics: Pavey adds to UK record collection

Briton follows up Bekele's world indoor best to earn the approval of watching old rival Radcliffe

Vigil honours the healing qualities of Afghanistan's al-Qa'ida cemetery

There are new graves at the al-Qa'ida cemetery, the shrine to the "martyrs" who had died fighting in the US-led invasion four years ago. The fresh mounds of earth were dug for those killed in the ferocious fighting of the recent months as war returned to Afghanistan.

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Independent Travel
Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
Burgundy, the River Rhone & Provence
Prague, Budapest and Vienna
Lake Garda
3.	Provence 6 nights B&B by train from £599pp
Prices correct as of 12 March 2015
Election 2015: How many of the Government's coalition agreement promises have been kept?

Promises, promises

But how many coalition agreement pledges have been kept?
The Gaza fisherman who built his own reef - and was shot dead there by an Israeli gunboat

The death of a Gaza fisherman

He built his own reef, and was fatally shot there by an Israeli gunboat
Saudi Arabia's airstrikes in Yemen are fuelling the Gulf's fire

Saudi airstrikes are fuelling the Gulf's fire

Arab intervention in Yemen risks entrenching Sunni-Shia divide and handing a victory to Isis, says Patrick Cockburn
Zayn Malik's departure from One Direction shows the perils of fame in the age of social media

The only direction Zayn could go

We wince at the anguish of One Direction's fans, but Malik's departure shows the perils of fame in the age of social media
Young Magician of the Year 2015: Meet the schoolgirl from Newcastle who has her heart set on being the competition's first female winner

Spells like teen spirit

A 16-year-old from Newcastle has set her heart on being the first female to win Young Magician of the Year. Jonathan Owen meets her
Jonathan Anderson: If fashion is a cycle, this young man knows just how to ride it

If fashion is a cycle, this young man knows just how to ride it

British designer Jonathan Anderson is putting his stamp on venerable house Loewe
Number plates scheme could provide a licence to offend in the land of the free

Licence to offend in the land of the free

Cash-strapped states have hit on a way of making money out of drivers that may be in collision with the First Amendment, says Rupert Cornwell
From farm to fork: Meet the Cornish fishermen, vegetable-growers and butchers causing a stir in London's top restaurants

From farm to fork in Cornwall

One man is bringing together Cornwall's most accomplished growers, fishermen and butchers with London's best chefs to put the finest, freshest produce on the plates of some of the country’s best restaurants
Robert Parker interview: The world's top wine critic on tasting 10,000 bottles a year, absurd drinking notes and New World wannabes

Robert Parker interview

The world's top wine critic on tasting 10,000 bottles a year, absurd drinking notes and New World wannabes
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Don't believe the stereotype - or should you?

We exaggerate regional traits and turn them into jokes - and those on the receiving end are in on it too, says DJ Taylor
How to make your own Easter egg: Willie Harcourt-Cooze shares his chocolate recipes

How to make your own Easter egg

Willie Harcourt-Cooze talks about his love affair with 'cacao' - and creates an Easter egg especially for The Independent on Sunday
Bill Granger recipes: Our chef declares barbecue season open with his twist on a tradtional Easter Sunday lamb lunch

Bill Granger's twist on Easter Sunday lunch

Next weekend, our chef plans to return to his Aussie roots by firing up the barbecue
Joe Marler: 'It's the way I think the game should be played'

Joe Marler: 'It's the way I think the game should be played'

The England prop relives the highs and lows of last Saturday's remarkable afternoon of Six Nations rugby
Cricket World Cup 2015: Has the success of the tournament spelt the end for Test matches?

Cricket World Cup 2015

Has the success of the tournament spelt the end for Test matches?
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Michael Calvin's Last Word

Justin Gatlin knows the price of everything, the value of nothing