Life and Style

Cough and cold sufferers are being urged to check their medicines after a manufacturing fault may have led to small pieces of plastic contaminating some batches, health officials have said.

S&N remains comparatively dull

The Investment Column

Huntingdon faces US test

Huntingdon Life Sciences, the animal testing group which faces losing its UK licence following a Home Office investigation into animal cruelty, will come under new pressure in the US on Monday.

Cortecs in brittle bone advance

Cortecs International yesterday took a step closer to launching the world's first pill for brittle bone disease. Shares in the drug delivery and diagnostics group jumped 10 per cent to 268.5p after it announced positive results from an eagerly awaited study on its osteoporosis treatment, Macritonin.

Blood clot risk from HRT

Women on hormone replacement therapy face an increased risk of blood clots in the legs and lungs during their first year of treatment, a study reveals today. The risk is highest during the first six months when a woman using HRT is four or five times more likely to suffer clots than a non-user. This falls to a three-fold greater risk after six months. After a year, the risk to HRT users is no more than it is for non-users.

Shire buys US drugs delivery firm for pounds 105m

Shire Pharmaceuticals, the small group floated a year ago, is to increase its size by more than two-thirds following a deal to pay up to $170m (pounds 105m) for Pharmavene, a US drugs delivery company based in Maryland.

The Investment column: Medeva's big gamble should pay off

Shareholders in Medeva have suffered a stomach-churning voyage over the years, but signs that the drugs group has been steering a steadier course have grown much clearer of late. Market concerns have centred on methylphenidate, the generic form of Ritalin, the controversial treatment for unruly children made by Novartis. It is thought to have represented over two-thirds of group profits in the past, but Medeva's 70 per cent market share could be under attack from three competitors by next year, with Johnson Matthey potentially ready to enter the market with a rival product as early as this summer.

And so to bed: Ovaltine heads for disposal

Drugs group plans pounds 3bn sell-off of non-core brands

Why good names mean a good deal

Against the background of agreeing valuations, harmonising management structures, squaring the regulators and sugaring the pill of job losses, the subject of corporate identity might seem the last of anybody's concerns when it comes to mergers and acquisitions.

Doc swaps stethoscope for a pounds 50bn briefcase

City & Business

Ciba-Geigy and Sandoz to merge into pounds 40bn giant

Pharmaceutical fusion: Biggest merger in history will create `Novartis', the world's second-largest drugs group, while bid spotlight turns on Zeneca
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video... and it wasn't good news for many of them
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New documents from the late Robin Williams' estate stipulate a restriction on his image, or any likeness of it, being used until 2039
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Chelsea
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people Ex-wife of John Lennon has died at her home in Spain
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Nick Clegg on the campaign trail in Glasgow on Wednesday; he says education is his top priority
peopleNick Clegg remains optimistic despite dismal Lib Dem poll ratings
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Buttoned up: Ryan Reynolds with Helen Mirren in ‘Woman in Gold’
filmFor every box-office smash in his Hollywood career, there's always been a misconceived let-down. Now he says it's time for a reboot
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Actress Julianne Moore wins the Best Actress in a Leading Role Award for 'Still Alice' during the 87th Annual Academy Awards in Hollywood, California
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Sport
Ross Barkley
footballPaul Scholes says it's time for the Everton playmaker to step up and seize the England No 10 shirt
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'We will fix it': mice in the 1970s children’s programme Bagpuss
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Independent Travel
Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
Burgundy, the River Rhone & Provence
Prague, Budapest and Vienna
Lake Garda
3.	Provence 6 nights B&B by train from £599pp
Prices correct as of 12 March 2015
War with Isis: Iraq declares victory in the battle for Tikrit - but militants make make ominous advances in neighbouring Syria's capital

War with Isis

Iraq declares victory in the battle for Tikrit - but militants make make ominous advances in neighbouring Syria
Scientists develop mechanical spring-loaded leg brace to improve walking

A spring in your step?

Scientists develop mechanical leg brace to help take a load off
Peter Ackroyd on Alfred Hitchcock: How London shaped the director's art and obsessions

Peter Ackroyd on Alfred Hitchcock

Ackroyd has devoted his literary career to chronicling the capital and its characters. He tells John Walsh why he chose the master of suspense as his latest subject
Ryan Reynolds interview: The actor is branching out with Nazi art-theft drama Woman in Gold

Ryan Reynolds branches out in Woman in Gold

For every box-office smash in Ryan Reynolds' Hollywood career, there's always been a misconceived let-down. It's time for a rethink and a reboot, the actor tells James Mottram
Why Robin Williams safeguarded himself against a morbid trend in advertising

Stars safeguard against morbid advertising

As film-makers and advertisers make increasing posthumous use of celebrities' images, some stars are finding new ways of ensuring that they rest in peace
The UK horticulture industry is facing a skills crisis - but Great Dixter aims to change all that

UK horticulture industry facing skills crisis

Great Dixter manor house in East Sussex is encouraging people to work in the industry by offering three scholarships a year to students, as well as generous placements
Hack Circus aims to turn the rule-abiding approach of TED talks on its head

Hack Circus: Technology, art and learning

Hack Circus aims to turn the rule-abiding approach of TED talks on its head. Rhodri Marsden meets mistress of ceremonies Leila Johnston
Sevenoaks is split over much-delayed decision on controversial grammar school annexe

Sevenoaks split over grammar school annexe

If Weald of Kent Grammar School is given the go-ahead for an annexe in leafy Sevenoaks, it will be the first selective state school to open in 50 years
10 best compact cameras

A look through the lens: 10 best compact cameras

If your smartphone won’t quite cut it, it’s time to invest in a new portable gadget
Paul Scholes column: Ross Barkley played well against Italy but he must build on that. His time to step up and seize that England No 10 shirt is now

Paul Scholes column

Ross Barkley played well against Italy but he must build on that. His time to step up and seize that England No 10 shirt is now
Why Michael Carrick is still proving an enigma for England

Why Carrick is still proving an enigma for England

Manchester United's talented midfielder has played international football for almost 14 years yet, frustratingly, has won only 32 caps, says Sam Wallace
Tracey Neville: The netball coach who is just as busy as her brothers, Gary and Phil

Tracey Neville is just as busy as her brothers, Gary and Phil

The former player on how she is finding time to coach both Manchester Thunder in the Superleague and England in this year's World Cup
General Election 2015: The masterminds behind the scenes

The masterminds behind the election

How do you get your party leader to embrace a message and then stick to it? By employing these people
Machine Gun America: The amusement park where teenagers go to shoot a huge range of automatic weapons

Machine Gun America

The amusement park where teenagers go to shoot a huge range of automatic weapons
The ethics of pet food: Why are we are so selective in how we show animals our love?

The ethics of pet food

Why are we are so selective in how we show animals our love?