Life and Style

The sight of thousands of people with previously incurable forms of blindness could be saved thanks to a pioneering new gene therapy that requires just one operation.

Toughest Case: Mr Ken Nischal, head of clinical and academic ophthalmology, Great Ormond Street Hospital

I'm an ophthalmologist specially trained in paediatrics at Great Ormond Street Hospital. The eye is separated into components and I'm an anterior segment specialist, which is basically the front of the eye.

What now for the miners? At the surface, a taxing new life will begin

The men trapped underground for two months face many weeks of adjustment once they are rescued

Cathy John: My diagnosis with MS has taught me the wisdom of 'gathering ye rosebuds while ye may'

Tolstoy once quoted an Eastern parable, which he felt summed up the three responses to the utter absurdity of life in light of the certainty of death.

The death of my friend Karen

Karen Woo and her nine colleagues were bringing medical care to the poorest communities of a ravaged nation they had grown to love when they were ambushed and shot dead, one by one

Alarm at attacks on guide dogs

Guide dogs for the blind are being attacked by other dogs at the rate of three a month, a review has found.

Laser-free 'cure' for short sight

A new method of correcting short sight could be better and safer than laser eye surgery, experts say.

Akram Khan, Sadler's Wells, London

Akram Khan's Gnosis is built around images of blindness. And what images! It's a work that goes from the grand strength of co-star Yoshie Sunahata, swinging her arms as if beating a great drum, to Khan's astonishing evocation of death by fire, trembling and shaking like flames in the wind.

The nurses who make Alder Hey such a special place

The mere thought of working as a nurse in a major children's hospital is enough to bring tears to some people's eyes. For Joan Grogan, craniofacial neurological nurse specialist at Alder Hey, there is one saving grace - the children both arrive and leave looking healthy. "Often the children are so young they don't even know what's happening," she adds. "They don't like the nil-by-mouth rule before the anaesthetic, but that is often their only gripe."

First Person: 'I hear sounds in colour'

Angela Purll, 28

Damage to Brown's eye raises questions about his future

And Prime Minister will have to repay some of his expenses claims, according to the BBC

Ray Hazan: We need to see our way to supporting ex-Servicemen

Sight loss can be devastating. When someone loses their sight they face a long, challenging journey of rehabilitation. Emotionally, they may feel isolated and frustrated by their situation. In practical terms, they will need to re-learn many of the everyday tasks they once took for granted. Today, on World Sight Day, I'd like to urge people to think about how we can best support ex-Service men and women who lose their sight, whether in combat or later life.

Letters: Teachers' morale

Crushing negativity that destroys teachers' morale

Ian Birrell: The NHS is flawed. Here's the evidence...

When our writer last week revealed his family's experiences with the health service, it provoked a huge debate. The reaction underlines his case that the NHS may be precious – but it is in urgent need of surgery

Abdullah's supporters threaten to take up arms over 'rigged' election

In northern Afghanistan, where opposition to Hamid Karzai is strong, the mood is darkening

Rival claims of victory stoke tensions after Afghan vote

Plea to wait for official election result ignored by President Karzai and his chief challenger Abdullah
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Brendan O'Carroll as Agnes Brown in the 2014 Mrs Brown's Boys Christmas special
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Members and supporters of the lesbian, gay, bisexual, transgender (LGBT) community walk with a rainbow flag during a rally in July
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Chelsea midfielder Cesc Fabregas
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Day In a Page

Independent Travel
Burgundy, the River Rhone & Provence – Five-star MS Swiss Corona 7 nights from £999pp
Lake Como St Moritz & the Bernina Express 7 nights from £809pp
Vietnam
Lake Maggiore, Orta & the Matterhorn 7 nights from £939pp
South Africa
Spain
Prices correct as of 19 December 2014
A Christmas without hope: Fears grow in Gaza that the conflict with Israel will soon reignite

Christmas without hope

Gaza fears grow that conflict with Israel will soon reignite
After 150 years, you can finally visit the grisliest museum in the country

The 'Black Museum'

After 150 years, you can finally visit Britain's grisliest museum
No ho-ho-hos with Nick Frost's badass Santa

No ho-ho-hos with Nick Frost's badass Santa

Doctor Who Christmas Special TV review
Chilly Christmas: Swimmers take festive dip for charity

Chilly Christmas

Swimmers dive into freezing British waters for charity
Veterans' hostel 'overwhelmed by kindness' for festive dinner

Homeless Veterans appeal

In 2010, Sgt Gary Jamieson stepped on an IED in Afghanistan and lost his legs and an arm. He reveals what, and who, helped him to make a remarkable recovery
Isis in Iraq: Yazidi girls killing themselves to escape rape and imprisonment by militants

'Jilan killed herself in the bathroom. She cut her wrists and hanged herself'

Yazidi girls killing themselves to escape rape and imprisonment
Ed Balls interview: 'If I think about the deficit when I'm playing the piano, it all goes wrong'

Ed Balls interview

'If I think about the deficit when I'm playing the piano, it all goes wrong'
He's behind you, dude!

US stars in UK panto

From David Hasselhoff to Jerry Hall
Grace Dent's Christmas Quiz: What are you – a festive curmudgeon or top of the tree?

Grace Dent's Christmas Quiz

What are you – a festive curmudgeon or top of the tree?
Nasa planning to build cloud cities in airships above Venus

Nasa planning to build cloud cities in airships above Venus

Planet’s surface is inhospitable to humans but 30 miles above it is almost perfect
Surrounded by high-rise flats is a little house filled with Lebanon’s history - clocks, rifles, frogmen’s uniforms and colonial helmets

Clocks, rifles, swords, frogmen’s uniforms

Surrounded by high-rise flats is a little house filled with Lebanon’s history
Return to Gaza: Four months on, the wounds left by Israel's bombardment have not yet healed

Four months after the bombardment, Gaza’s wounds are yet to heal

Kim Sengupta is reunited with a man whose plight mirrors the suffering of the Palestinian people
Gastric surgery: Is it really the answer to the UK's obesity epidemic?

Is gastric surgery really the answer to the UK's obesity epidemic?

Critics argue that it’s crazy to operate on healthy people just to stop them eating
Homeless Veterans appeal: Christmas charity auction Part 2 - now LIVE

Homeless Veterans appeal: Christmas charity auction

Bid on original art, or trips of a lifetime to Africa or the 'Corrie' set, and help Homeless Veterans
Pantomime rings the changes to welcome autistic theatre-goers

Autism-friendly theatre

Pantomime leads the pack in quest to welcome all