Life and Style

The sight of thousands of people with previously incurable forms of blindness could be saved thanks to a pioneering new gene therapy that requires just one operation.

Toughest Case: Mr Ken Nischal, head of clinical and academic ophthalmology, Great Ormond Street Hospital

I'm an ophthalmologist specially trained in paediatrics at Great Ormond Street Hospital. The eye is separated into components and I'm an anterior segment specialist, which is basically the front of the eye.

What now for the miners? At the surface, a taxing new life will begin

The men trapped underground for two months face many weeks of adjustment once they are rescued

Cathy John: My diagnosis with MS has taught me the wisdom of 'gathering ye rosebuds while ye may'

Tolstoy once quoted an Eastern parable, which he felt summed up the three responses to the utter absurdity of life in light of the certainty of death.

The death of my friend Karen

Karen Woo and her nine colleagues were bringing medical care to the poorest communities of a ravaged nation they had grown to love when they were ambushed and shot dead, one by one

Alarm at attacks on guide dogs

Guide dogs for the blind are being attacked by other dogs at the rate of three a month, a review has found.

Laser-free 'cure' for short sight

A new method of correcting short sight could be better and safer than laser eye surgery, experts say.

Akram Khan, Sadler's Wells, London

Akram Khan's Gnosis is built around images of blindness. And what images! It's a work that goes from the grand strength of co-star Yoshie Sunahata, swinging her arms as if beating a great drum, to Khan's astonishing evocation of death by fire, trembling and shaking like flames in the wind.

The nurses who make Alder Hey such a special place

The mere thought of working as a nurse in a major children's hospital is enough to bring tears to some people's eyes. For Joan Grogan, craniofacial neurological nurse specialist at Alder Hey, there is one saving grace - the children both arrive and leave looking healthy. "Often the children are so young they don't even know what's happening," she adds. "They don't like the nil-by-mouth rule before the anaesthetic, but that is often their only gripe."

First Person: 'I hear sounds in colour'

Angela Purll, 28

Damage to Brown's eye raises questions about his future

And Prime Minister will have to repay some of his expenses claims, according to the BBC

Ray Hazan: We need to see our way to supporting ex-Servicemen

Sight loss can be devastating. When someone loses their sight they face a long, challenging journey of rehabilitation. Emotionally, they may feel isolated and frustrated by their situation. In practical terms, they will need to re-learn many of the everyday tasks they once took for granted. Today, on World Sight Day, I'd like to urge people to think about how we can best support ex-Service men and women who lose their sight, whether in combat or later life.

Letters: Teachers' morale

Crushing negativity that destroys teachers' morale

Ian Birrell: The NHS is flawed. Here's the evidence...

When our writer last week revealed his family's experiences with the health service, it provoked a huge debate. The reaction underlines his case that the NHS may be precious – but it is in urgent need of surgery

Abdullah's supporters threaten to take up arms over 'rigged' election

In northern Afghanistan, where opposition to Hamid Karzai is strong, the mood is darkening

Rival claims of victory stoke tensions after Afghan vote

Plea to wait for official election result ignored by President Karzai and his chief challenger Abdullah
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Independent Travel
Pompeii, Capri & the Bay of Naples
Seven Cities of Italy
Burgundy, the River Rhone & Provence
Prague, Budapest and Vienna
Lake Garda
Minoan Crete and Santorini
Prices correct as of 1 May 2015
General Election 2015: Ed Miliband's unlikely journey from hapless geek to heart-throb

Miliband's unlikely journey from hapless geek to heart-throb

He was meant to be Labour's biggest handicap - but has become almost an asset
General Election 2015: A guide to the smaller parties, from the the National Health Action Party to the Church of the Militant Elvis Party

On the margins

From Militant Elvis to Women's Equality: a guide to the underdogs standing in the election
Amr Darrag: Ex-Muslim Brotherhood minister in exile still believes Egypt's military regime can be replaced with 'moderate' Islamic rule

'This is the battle of young Egypt for the future of our country'

Ex-Muslim Brotherhood minister Amr Darrag still believes the opposition can rid Egypt of its military regime and replace it with 'moderate' Islamic rule, he tells Robert Fisk
Why patients must rely less on doctors: Improving our own health is the 'blockbuster drug of the century'

Why patients must rely less on doctors

Improving our own health is the 'blockbuster drug of the century'
Sarah Lucas is the perfect artist to represent Britain at the Venice Biennale

Flesh in Venice

Sarah Lucas has filled the British pavilion at the Venice Biennale with slinky cats and casts of her female friends' private parts. It makes you proud to be a woman, says Karen Wright
11 best anti-ageing day creams

11 best anti-ageing day creams

Slow down the ageing process with one of these high-performance, hardworking anti-agers
Juventus 2 Real Madrid 1: Five things we learnt, including Iker Casillas is past it and Carlos Tevez remains effective

Juventus vs Real Madrid

Five things we learnt from the Italian's Champions League first leg win over the Spanish giants
Ashes 2015: Test series looks a lost cause for England... whoever takes over as ECB director of cricket

Ashes series looks a lost cause for England...

Whoever takes over as ECB director of cricket, says Stephen Brenkley
Fishing for votes with Nigel Farage: The Ukip leader shows how he can work an audience as he casts his line to the disaffected of Grimsby

Fishing is on Nigel Farage's mind

Ukip leader casts a line to the disaffected
Who is bombing whom in the Middle East? It's amazing they don't all hit each other

Who is bombing whom in the Middle East?

Robert Fisk untangles the countries and factions
China's influence on fashion: At the top of the game both creatively and commercially

China's influence on fashion

At the top of the game both creatively and commercially
Lord O’Donnell: Former cabinet secretary on the election and life away from the levers of power

The man known as GOD has a reputation for getting the job done

Lord O'Donnell's three principles of rule
Rainbow shades: It's all bright on the night

Rainbow shades

It's all bright on the night
'It was first time I had ever tasted chocolate. I kept a piece, and when Amsterdam was liberated, I gave it to the first Allied soldier I saw'

Bread from heaven

Dutch survivors thank RAF for World War II drop that saved millions
Britain will be 'run for the wealthy and powerful' if Tories retain power - Labour

How 'the Axe' helped Labour

UK will be 'run for the wealthy and powerful' if Tories retain power