Life and Style

The sight of thousands of people with previously incurable forms of blindness could be saved thanks to a pioneering new gene therapy that requires just one operation.

Letters: Time for a change in drugs policy

'The Wire' comes to the English seaside

The Sonnets: 152

By William Shakespeare

Oops, we did it again - Why we make mistakes

Why do we make stupid mistakes? A new book says people have design faults that inevitably lead to slip-ups – but we can train ourselves to avoid them.

Blindness cure to be trialled in UK



A revolutionary new treatment that could cure certain types of blindness is to be trialled in Britain, it was announced.

Matthew Wadsworth/Carolyn Sampson, Wigmore Hall, London

Reviewed by Michael Church

UK at risk of losing lead in stem cell research

Britain's attempts to take stem cell research from the laboratory to the clinic are being undermined by government red tape and a lack of interest from City investors, according to experts meeting in London today.

Blindness (18)

Dystopian Breakdown, Part I. An epidemic of blindness grips a city population, and its first victims are herded into a ramshackle facility under guard.

Britain in push to bring Syria in from the cold

Foreign Secretary David Miliband accepts invitation to visit Damascus after 'important change in approach'

She supported the NHS – then it let her down

A two-year delay in approving a drug has cost one elderly woman her sight

How to cut the cost of glasses, contacts and laser eye surgery

You can improve your sight without breaking the bank – if you know where to look, says Kate Hughes

The Weasel: A spectacle of myself

The striking depiction of the Weasel by Lucinda Rogers that illuminates this column on a weekly basis is, of course, an impeccably accurate likeness of the author. But if compelled to make a criticism of my likeness I might point out that the specs are wrong. I went through my John Lennon phase over two decades ago. Though fine for the sardonic Scouser's beaky nose, they didn't do much for the Weaselian features, even with the oh-so-cool (or so I thought) amendment of a blue tint to the lenses. After that, I had a brief flirtation with contact lenses. This was even less of a success since the soft lenses failed to correct my astigmatism. "Have you ever considered wearing glasses with your contact lenses?" inquired the ophthalmologist. Whenever I've told the story to opticians they find nothing amusing in it at all.

Trail Of The Unexpected: The game is afoot... Sherlock Holmes and the FA Cup connection

As Portsmouth FC take on Cardiff City in this afternoon's FA Cup final, the players from Pompey (as the team is always known) may find themselves watched over by the spirit of an erstwhile goalkeeper and leading light of Victorian England.

The blind man who was given the gift of sight by gene therapy

A pioneering gene therapy trial has helped a blind man to see in a breakthrough that brings hope to millions affected by eye diseases. British scientists have claimed a world first for the revolutionary treatment, which involved a single injection into the retina at the back of the eye.

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Day In a Page

Burgundy, the River Rhone & Provence – MS Swiss Corona - seven nights from £999pp
Lake Maggiore, Orta and the Matterhorn – seven nights from £899pp
Sicily – seven nights from £939pp
Pompeii, Capri and the Bay of Naples - seven nights from £799pp
Istanbul Ephesus & Troy – six nights from £859pp
Mary Rose – two nights from £319pp
Save the tiger: The animals bred for bones on China’s tiger farms

The animals bred for bones on China’s tiger farms

The big cats kept in captivity to perform for paying audiences and then, when dead, their bodies used to fortify wine
A former custard factory, a Midlands bog and a Leeds cemetery all included in top 50 hidden spots in the UK

A former custard factory, a Midlands bog and a Leeds cemetery

Introducing the top 50 hidden spots in Britain
Ebola epidemic: Plagued by fear

Ebola epidemic: Plagued by fear

How a disease that has claimed fewer than 2,000 victims in its history has earned a place in the darkest corner of the public's imagination
Chris Pratt: From 'Parks and Recreation' to 'Guardians of the Galaxy'

From 'Parks and Recreation' to 'Guardians of the Galaxy'

He was homeless in Hawaii when he got his big break. Now the comic actor Chris Pratt is Hollywood's new favourite action star
How live cinema screenings can boost arts audiences

How live cinema screenings can boost arts audiences

Broadcasting plays and exhibitions to cinemas is a sure-fire box office smash
Shipping container hotels: Pop-up hotels filling a niche

Pop-up hotels filling a niche

Spending the night in a shipping container doesn't sound appealing, but these mobile crash pads are popping up at the summer's biggest events
Native American headdresses are not fashion accessories

Feather dust-up

A Canadian festival has banned Native American headwear. Haven't we been here before?
Boris Johnson's war on diesel

Boris Johnson's war on diesel

11m cars here run on diesel. It's seen as a greener alternative to unleaded petrol. So why is London's mayor on a crusade against the black pump?
5 best waterproof cameras

Splash and flash: 5 best waterproof cameras

Don't let water stop you taking snaps with one of these machines that will take you from the sand to meters deep
Louis van Gaal interview: Manchester United manager discusses tactics and rebuilding after the David Moyes era

Louis van Gaal interview

Manchester United manager discusses tactics and rebuilding after the David Moyes era
Will Gore: The goodwill shown by fans towards Alastair Cook will evaporate rapidly if India win the series

Will Gore: Outside Edge

The goodwill shown by fans towards Alastair Cook will evaporate rapidly if India win the series
The children were playing in the street with toy guns. The air strikes were tragically real

The air strikes were tragically real

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Britain as others see us

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How did our legends really begin?

Applying the theory of evolution to the world's many mythologies
Watch out: Lambrusco is back on the menu

Lambrusco is back on the menu

Naff Seventies corner-shop staple is this year's Aperol Spritz