Life and Style

The sight of thousands of people with previously incurable forms of blindness could be saved thanks to a pioneering new gene therapy that requires just one operation.

Letters: Time for a change in drugs policy

'The Wire' comes to the English seaside

The Sonnets: 152

By William Shakespeare

Oops, we did it again - Why we make mistakes

Why do we make stupid mistakes? A new book says people have design faults that inevitably lead to slip-ups – but we can train ourselves to avoid them.

Blindness cure to be trialled in UK



A revolutionary new treatment that could cure certain types of blindness is to be trialled in Britain, it was announced.

Matthew Wadsworth/Carolyn Sampson, Wigmore Hall, London

Reviewed by Michael Church

UK at risk of losing lead in stem cell research

Britain's attempts to take stem cell research from the laboratory to the clinic are being undermined by government red tape and a lack of interest from City investors, according to experts meeting in London today.

Blindness (18)

Dystopian Breakdown, Part I. An epidemic of blindness grips a city population, and its first victims are herded into a ramshackle facility under guard.

Britain in push to bring Syria in from the cold

Foreign Secretary David Miliband accepts invitation to visit Damascus after 'important change in approach'

She supported the NHS – then it let her down

A two-year delay in approving a drug has cost one elderly woman her sight

How to cut the cost of glasses, contacts and laser eye surgery

You can improve your sight without breaking the bank – if you know where to look, says Kate Hughes

The Weasel: A spectacle of myself

The striking depiction of the Weasel by Lucinda Rogers that illuminates this column on a weekly basis is, of course, an impeccably accurate likeness of the author. But if compelled to make a criticism of my likeness I might point out that the specs are wrong. I went through my John Lennon phase over two decades ago. Though fine for the sardonic Scouser's beaky nose, they didn't do much for the Weaselian features, even with the oh-so-cool (or so I thought) amendment of a blue tint to the lenses. After that, I had a brief flirtation with contact lenses. This was even less of a success since the soft lenses failed to correct my astigmatism. "Have you ever considered wearing glasses with your contact lenses?" inquired the ophthalmologist. Whenever I've told the story to opticians they find nothing amusing in it at all.

Trail Of The Unexpected: The game is afoot... Sherlock Holmes and the FA Cup connection

As Portsmouth FC take on Cardiff City in this afternoon's FA Cup final, the players from Pompey (as the team is always known) may find themselves watched over by the spirit of an erstwhile goalkeeper and leading light of Victorian England.

The blind man who was given the gift of sight by gene therapy

A pioneering gene therapy trial has helped a blind man to see in a breakthrough that brings hope to millions affected by eye diseases. British scientists have claimed a world first for the revolutionary treatment, which involved a single injection into the retina at the back of the eye.

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World's most lethal spider found under a bunch of bananas

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<p>Jonathan Ross</p>
<p>Jonathan Ross (or Wossy, as he’s affectionately known) has been on television and radio for an extraordinarily long time, working on a seat in the pantheon of British presenters. Hosting Friday Night with Jonathan Ross for nine years, Ross has been in everything from the video game Fable to Phineas and Ferb. So it’s probably not so surprising that Ross studied at Southampton College of Art (since rebranded Southampton Solent), a university known nowadays for its media production courses.</p>
<p>However, after leaving Solent, Ross studied History at the School of Slavonic and East European Studies, now part of the UCL, a move that was somewhat out of keeping with the rest of his career. Ross was made a fellow of the school in 2006 in recognition of his services to broadcasting.</p>
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Paul Nuttall, left, is seen as one of Ukip's key weapons in selling the party to the North of England
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Oscar Pistorius sentencing: The athlete's wealth and notoriety have provoked a long overdue debate on South African prisons

'They poured water on, then electrified me...'

If Oscar Pistorius is sent to jail, his experience will not be that of other inmates
James Wharton: The former Guard now fighting discrimination against gay soldiers

The former Guard now fighting discrimination against gay soldiers

Life after the Army has brought new battles for the LGBT activist James Wharton
Ebola in the US: Panic over the virus threatens to infect President Obama's midterms

Panic over Ebola threatens to infect the midterms

Just one person has died, yet November's elections may be affected by what Republicans call 'Obama's Katrina', says Rupert Cornwell
Premier League coaches join the RSC to swap the tricks of their trades

Darling, you were fabulous! But offside...

Premier League coaches are joining the RSC to learn acting skills, and in turn they will teach its actors to play football. Nick Clark finds out why
How to dress with authority: Kirsty Wark and Camila Batmanghelidjh discuss the changing role of fashion in women's workwear

How to dress with authority

Kirsty Wark and Camila Batmanghelidjh discuss the changing role of fashion in women's workwear
New book on Joy Division's Ian Curtis sheds new light on the life of the late singer

New book on Ian Curtis sheds fresh light on the life of the late singer

'Joy Division were making art... Ian was for real' says author Jon Savage
Sean Harris: A rare interview with British acting's secret weapon

Sean Harris: A rare interview with British acting's secret weapon

The Bafta-winner talks Hollywood, being branded a psycho, and how Barbra Streisand is his true inspiration
Tim Minchin, interview: The musician, comedian and world's favourite ginger is on scorching form

Tim Minchin interview

For a no-holds-barred comedian who is scathing about woolly thinking and oppressive religiosity, he is surprisingly gentle in person
Boris Johnson's boozing won't win the puritan vote

Boris's boozing won't win the puritan vote

Many of us Brits still disapprove of conspicuous consumption – it's the way we were raised, says DJ Taylor
Ash frontman Tim Wheeler reveals how he came to terms with his father's dementia

Tim Wheeler: Alzheimer's, memories and my dad

Wheeler's dad suffered from Alzheimer's for three years. When he died, there was only one way the Ash frontman knew how to respond: with a heartfelt solo album
Hugh Bonneville & Peter James: 'Peter loves his classic cars; I've always pootled along fine with a Mini Metro. I think I lack his panache'

How We Met: Hugh Bonneville & Peter James

'Peter loves his classic cars; I've always pootled along fine with a Mini Metro. I think I lack his panache'
Bill Granger recipes: Our chef's heavenly crab dishes don't need hours of preparation

Bill Granger's heavenly crab recipes

Scared off by the strain of shelling a crab? Let a fishmonger do the hard work so you can focus on getting the flavours right
Radamel Falcao: How faith and love drive the Colombian to glory

Radamel Falcao: How faith and love drive the Colombian to glory

After a remarkable conversion from reckless defender to prolific striker, Monaco's ace says he wants to make his loan deal at Old Trafford permanent
Terry Venables: Premier League managers must not be allowed to dictate who plays and who does not play for England

Terry Venables column

Premier League managers must not be allowed to dictate who plays and who does not play for England
The Inside Word: Brendan Rodgers looks to the future while Roy Hodgson is ghost of seasons past

Michael Calvin's Inside Word

Brendan Rodgers looks to the future while Roy Hodgson is ghost of seasons past