Life and Style Peanut allergy affects around half a million people in the UK

Thousands of people suffering from peanut allergies could be saved from potentially fatal allergic reactions thanks to a revolutionary new therapy spearheaded by British doctors.

Everything is about to change forever: My experience of gender dysphoria

Gender reassignment isn't something to take lightly, it is a necessity. And a life change I know I will be judged for

Children can 'grow out of' autism, psychologists say, challenging the established view that it is a permanent, incurable condition

Identifying transition from 'autistic' to functioning like their peers could lead to effective therapies

Last night's viewing - Numb: Simon Amstell Live at the BBC, BBC4; Climbed Every Mountain: The Story Behind The Sound of Music, BBC2

Is self-consciousness contagious? When I started watching Numb: Simon Amstell Live at the BBC I was feeling pretty relaxed. But by the end I was almost as knotted with anxieties as he is. How would he feel if I criticised his voice, for example? He can't do anything about it, after all – that high-pitched, thready delivery which sits just a tweak away from a whine. And I know that he's self-conscious about it because he mentioned it during the routine.

DVD: Peep Show: Series 8 (15)

It's still the best thing David Mitchell and Robert Webb have ever been involved in and it's probably, along with Father Ted, Channel 4's funniest sitcom.

Doubt cast on MS cannabis treatment

There is no strong evidence to back the use of cannabis extract in the treatment of multiple sclerosis (MS), it was claimed.

Nuchem Rosenberg: 'I thought it was coffee or something and he throws it in my face'

Rabbi who fought against child sex abuse is attacked with bleach

'Revenge' street assault comes one day after the conviction of prominent offender

An aerial view of the Coq d’Argent

Victim of Facebook stalker leapt to her death from rooftop restaurant

Rema Begum became distressed after her lifestyle was exposed to her Muslim parents

Cancer cells: New treatment offers hope

Cells from patients' own blood spur cancer remissions

Nine leukemia patients are cancer-free after being treated with genetically-altered versions of their own immune cells, giving strength to a promising new approach for treating the blood cancer.

The Weekend’s Viewing: Peep Show's Pompous and Punchable deliver a tour de force of squirm

Peep Show, Sun, Channel 4 // Him & Her, Sun, BBC3 // 4Funnies: Dr Brown, Fri, Channel 4

IoS album review: Alicia Keys, Girl on Fire (RCA)

Keys doesn’t do “cryptic”. Girl on Fire is about fresh beginnings, hence tracks called “New Day” and “Brand New Me”, and, at one cringeworthy point, the voice of her baby.

Experts have said the figures could indicate a rise in the number of cases, and that this could be due to an increase in anxiety and stress, possibly caused by long working hours and the recession

Stress and economic climate to blame as Westminster is named impotence capital of England

A study showed that 20 per cent of people seeking treatment for the problem live in the South East of England

Anti-psychotic drugs can lead to 'startling' weight gain

Ignorance over dose levels means patients can put on a stone in just eight weeks, inquiry finds

Patient care of schizophrenics at 'all-time low', claim experts

Last year almost 49,000 patients were detained against their will under the Mental Health Act 2007, the highest level since the act was introduced five years ago. Black and Afro-Caribbean men are disproportionately represented among those who were detained.

Brain damaged woman allowed to 'die with dignity', judge rules

A woman left with irreversible brain damage and diagnosed as being in a permanent vegetative state is to be allowed to die with dignity after a judge dismissed reports by two “shocked” therapy assistants that she may have repeatedly whispered the word "die".

Tonight's Viewing: Gay to Straight: Stacey Dooley in the USA, BBC3
50 Years of Bond Cars: a Top Gear Special, BBC2

Stacey’s innocence is part of the brand. Being startled is what she does best”

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people
Arts and Entertainment
Game Of Thrones
Uh-oh, winter is coming. Ouch, my eyes! Ygritte’s a goner. Lysa’s a goner. Tywin’s a goner. Look, a dragon
tvSpoiler warning: The British actor says viewers have 'not seen the last' of his character
Arts and Entertainment
'New Tricks' star Dennis Waterman is departing from the show after he completes filming on two more episodes
tvOnly remaining original cast-member to leave long-running series
Sport
Esteban Cambiasso makes it 3-3
premier league
Sport
The Etihad Stadium, home of Manchester City
premier leaguePlus updates from Everton vs Palace
News
people'I hated him during those times'
News
Britain's shadow chancellor Ed Balls (L) challenges reporter Rob Merrick for the ball during the Labour Party versus the media soccer match,
peopleReporter left bleeding after tackle from shadow Chancellor in annual political football match
Sport
Heskey's aim has improved since the end of his English football career

Long after his career in English football has ended, Emile Heskey's impotency in front of goal remains an object of ridicule.

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i100
News
Dame Vivienne Westwood has been raging pretty much all of her life
peopleFirst memoir extracts show she 'felt pressured' into going out with the Sex Pistols manager
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Scottish referendum: The Yes vote was the love that dared speak its name, but it was not to be

Despite the result, this is the end of the status quo

Boyd Tonkin on the fall-out from the Scottish referendum
Manolo Blahnik: The high priest of heels talks flats, Englishness, and why he loves Mary Beard

Manolo Blahnik: Flats, Englishness, and Mary Beard

The shoe designer who has been dubbed 'the patron saint of the stiletto'
The Beatles biographer reveals exclusive original manuscripts of some of the best pop songs ever written

Scrambled eggs and LSD

Behind The Beatles' lyrics - thanks to Hunter Davis's original manuscript copies
'Normcore' fashion: Blending in is the new standing out in latest catwalk non-trend

'Normcore': Blending in is the new standing out

Just when fashion was in grave danger of running out of trends, it only went and invented the non-trend. Rebecca Gonsalves investigates
Dance’s new leading ladies fight back: How female vocalists are now writing their own hits

New leading ladies of dance fight back

How female vocalists are now writing their own hits
Mystery of the Ground Zero wedding photo

A shot in the dark

Mystery of the wedding photo from Ground Zero
His life, the universe and everything

His life, the universe and everything

New biography sheds light on comic genius of Douglas Adams
Save us from small screen superheroes

Save us from small screen superheroes

Shows like Agents of S.H.I.E.L.D are little more than marketing tools
Reach for the skies

Reach for the skies

From pools to football pitches, rooftop living is looking up
These are the 12 best hotel spas in the UK

12 best hotel spas in the UK

Some hotels go all out on facilities; others stand out for the sheer quality of treatments
These Iranian-controlled Shia militias used to specialise in killing American soldiers. Now they are fighting Isis, backed up by US airstrikes

Widespread fear of Isis is producing strange bedfellows

Iranian-controlled Shia militias that used to kill American soldiers are now fighting Isis, helped by US airstrikes
Topshop goes part Athena poster, part last spring Prada

Topshop goes part Athena poster, part last spring Prada

Shoppers don't come to Topshop for the unique
How to make a Lego masterpiece

How to make a Lego masterpiece

Toy breaks out of the nursery and heads for the gallery
Meet the ‘Endies’ – city dwellers who are too poor to have fun

Meet the ‘Endies’ – city dwellers who are too poor to have fun

Urbanites are cursed with an acronym pointing to Employed but No Disposable Income or Savings
Paisley’s decision to make peace with IRA enemies might remind the Arabs of Sadat

Ian Paisley’s decision to make peace with his IRA enemies

His Save Ulster from Sodomy campaign would surely have been supported by many a Sunni imam