The Australian actor was quizzed about returning as the superhero on This Morning (10 April).
"I'd play this character for as long as anyone would let me, I've loved it so much," Hemsworth said.
"But the combination of this many characters in this Phase Three, as Marvel calls it, you'll never have this interaction with this many people again.
"Who knows what the future holds and whether they do prequels and sequels or whatever, I'd be open to anything. But right now, this is where we finish up."
Hemsworth made a similar admission while speaking on television in Australia recently, saying: "I won't be playing the character again.
"It's sort of a scary thought. This really seemed like this never-ending thing. And now it's potentially finishing."
Avengers: Endgame reaches cinemas 26 April. Read everything we know about the Infinity War sequel here.
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