") no-repeat center center;background-size:10px 16px;content:' '}@media(min-width:768px){.gBkjJh::before{display:none}}@media(min-width:1000px){.gdPcRA .taboola{display:none}}.jImJId .tp-container-inner,.jImJId .sc-1suqprf-0{position:relative;box-shadow:0 -22px 16px 22px rgba(255,255,255,0.95)}.jImJId.closed{display:none}.eZumoJ{position:fixed;top:0;left:0;z-index:2147483644;background:rgba(0,0,0,0.5);cursor:pointer;opacity:0;transition:opacity 300ms ease-in-out}.eZumoJ.overlay-background--open{width:100vw;height:100vh;opacity:1}.dRVLpc{--trans:300ms ease-in-out;position:fixed;top:0;left:0;z-index:2147483645;width:100vw;height:100vh;opacity:0;pointer-events:none;transform:translateY(-24px);transform-origin:top center;transition:transform var(--trans),opacity var(--trans)}.dRVLpc.overlay--open{opacity:1;transform:translateY(0);transition-delay:150ms}.dRVLpc.overlay--open>:first-child{pointer-events:auto}.cWTSTp .sc-17yxc4y-0{display:none}.cWTSTp:hover .sc-17yxc4y-0,.cWTSTp.bookmark-button-saved .sc-17yxc4y-0{display:block}.cWTSTp:hover .sc-17yxc4y-1,.cWTSTp.bookmark-button-saved .sc-17yxc4y-1{display:none}.cWTSTp.bookmark-button-saved .sc-17yxc4y-0{display:block}.cWTSTp.bookmark-button-saved .sc-17yxc4y-1{display:none}.cWTSTp.bookmark-button-saved:hover .sc-17yxc4y-0{display:none}.cWTSTp.bookmark-button-saved:hover .sc-17yxc4y-1{display:block}.czGZzO{--margin-x:12px;--modal-width:calc(100% - (var(--margin-x) * 2));--modal-max-width:351px;--padding:60px 16px 42px;--line-height:1.25;position:fixed;top:50%;left:50%;overflow:auto;width:var(--modal-width);max-width:var(--modal-max-width);max-height:100vh;box-sizing:border-box;padding:var(--padding);background-color:#eaf2f2;box-shadow:0 1px 1px rgba(0,0,0,0.5);line-height:var(--line-height);text-align:center;transform:translate(-50%,-50%)}@media(min-width:768px){.czGZzO{--modal-width:600px;--modal-max-width:none;--padding:72px 80px 64px;--line-height:1.2}}@media(min-width:1000px){.czGZzO{--modal-width:635px}}.kYjygs{--close-button-margin:15px;position:absolute;top:var(--close-button-margin);right:var(--close-button-margin);padding:10px}@media(min-width:768px){.kYjygs{--close-button-margin:24px}}.PPpcm{display:block;width:100%;max-width:437px;margin:0 0 20px}@media(min-width:768px){.PPpcm{margin-bottom:18px}}.cOYrQW{margin:0 0 30px;font:bold 26px/1.15 'Indy Serif','Indy Serif Fallback',serif}@media(min-width:768px){.cOYrQW{font:bold 28px/1.15 'Indy Serif','Indy Serif Fallback',serif}}.epOOte{display:block;width:100%;padding:0;margin:0 0 30px;font:normal 16px/1.44 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.epOOte{font:normal 20px/1.44 'Indy Sans','Indy Sans Fallback',sans-serif}}.fDiLAE{display:block;margin-top:30px;color:#222;font:normal 16px/normal 'Indy Sans','Indy Sans Fallback',sans-serif}.lcFPQp{padding:0}.dzPSOH{display:inline-block;width:32px;height:32px;color:#70a5a7}.dzPSOH button svg{width:32px;height:32px;margin:0}:not(.subscribed) .dzPSOH{margin:0 12px 0 0}.subscribed .dzPSOH{margin:0 0 16px 0}.lflWOn{display:block}@media(min-width:768px){.lflWOn{display:block}}.lflWOn:last-child button{margin-right:0}.lflWOn path{stroke:#fff}.jWuEbG button{margin-right:12px}@media(min-width:768px){.jWuEbG{display:none}.jWuEbG button{margin-right:12px}}.hgDTSg{display:flex;position:relative;justify-content:center}@media(min-width:768px){.hgDTSg{justify-content:flex-end;padding-top:12px;margin:0}}.hgDTSg svg{width:60%;height:60%;margin:20%;fill:#fff}.hgDTSg [type='facebook'] svg{width:100%;height:100%;margin:0}.hgDTSg amp-social-share{margin:0 6px;border-radius:50%;background:0;outline:0}.hgDTSg amp-social-share:first-of-type{margin-left:0}.hgDTSg amp-social-share:last-of-type{margin-right:0}@media(min-width:768px){.hgDTSg .share-mobile-only{display:none}}.hgDTSg .amp-social-share-bookmark svg{display:block;width:100%;height:100%;margin:0}.hgDTSg .amp-social-share-bookmark:hover{opacity:.85}.hgDTSg .amp-social-share-facebook{background:#627aac}.hgDTSg .amp-social-share-facebook:hover{background:#9cabcb}.hgDTSg .amp-social-share-twitter{--color:#4e4e4e;--color-alt:#919191;background:var(--color)}.hgDTSg .amp-social-share-twitter:hover{background:var(--color-alt)}.hgDTSg .amp-social-share-whatsapp{background:#25d366}.hgDTSg .amp-social-share-whatsapp:hover{background:#66e093}.hgDTSg .amp-social-share-whatsapp svg{width:70%;height:auto;margin:15%}.hgDTSg .amp-social-share-email{background:#ef4757}.hgDTSg .amp-social-share-email:hover{background:#f58992}.hgDTSg .amp-social-share-email svg path{stroke:#fff}.kdvWjb{display:flex}.sticky .kdvWjb{flex-direction:column}.bfkmcy{overflow:hidden;height:23px;margin-bottom:8px;border-bottom:0;clear:both}@media(min-width:768px){.bfkmcy{height:25px}}.fczuIa{display:inline-block;flex-shrink:0;margin:0 12px 0 0;font:bold 14px/normal 'Indy Sans','Indy Sans Fallback',sans-serif}.fczuIa::after{content:':'}.IOUwh{display:inline-block;margin-right:12px;margin-bottom:4px;color:#222;font:normal 14px/1.29 'Indy Sans','Indy Sans Fallback',sans-serif;text-decoration:underline}.IOUwh::first-letter {text-transform:capitalize}.izpdPv>p{margin:16px 0}.article-premium .izpdPv>p{line-height:27px}.izpdPv>h2{font-size:21px}.article-climate .izpdPv>h2{color:#ec1a2e}.article-sgi .izpdPv>h2{color:#ec1a2e}.izpdPv>p:first-child{margin-top:0}.izpdPv span:first-child~p:first-of-type{margin-top:0}.hQjaQn{display:flex;position:relative;max-width:100%;min-height:600px;justify-content:center;margin:0 auto;background-color:transparent;clear:both}@media(min-width:1000px){.hQjaQn{min-height:450px}}.teads .hQjaQn{display:block}.hQjaQn [data-mpu]{position:sticky;top:16px}@media(min-width:1000px){.jZcooN{display:none}}.jZcooN[data-mpu1]{min-height:600px}.jZcooN.pb-20{padding-bottom:20px}.hlPMMm{margin:0 0 24px;font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}.euTVax{font:bold 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}.jBfdop{overflow:hidden;width:100%;box-sizing:border-box;margin-bottom:16px}@media(min-width:768px){.jBfdop{max-width:634px}}@media(min-width:1250px){.jBfdop{max-width:622px}}.hKRbzg{width:100%;box-sizing:border-box;padding:8px 12px 12px;border-top:8px solid #ec1a2e;background-color:#fde8ea}@media(min-width:768px){.hKRbzg{padding-top:4px;padding-bottom:12px}}.cKIkhp{font:bold 22px/26px 'Indy Serif','Indy Serif Fallback',serif;margin:0 0 12px;text-align:center}@media(min-width:768px){.cKIkhp{font:bold 30px/34px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.048px;margin-bottom:12px;text-align:left}}.feSJtK{display:block;margin-bottom:12px}@media(min-width:768px){.feSJtK{display:none}}.bErStG{display:flex;width:100%;box-sizing:border-box;align-items:center;justify-content:center;gap:4px;background-color:#fde8ea;color:#ec1a2e}@media(min-width:768px){.bErStG{width:auto;justify-content:flex-start}}.vaVnf{display:block;font:bold 14px/20px 'Indy Sans','Indy Sans Fallback',sans-serif;text-decoration-line:underline;margin-block:0;text-align:center}.jWuFRk{display:inline-flex;align-items:center;justify-content:center;gap:4px}.jWuFRk:hover .sc-hez36s-5,.jWuFRk:hover .sc-a5wy94-0{color:#ac2a2c}.hKrnEq{font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}.dWUzhG{display:flex;width:100%;flex-direction:column}@media(min-width:768px){.dWUzhG{display:flow-root;gap:24px;transition:margin-bottom .3s ease-in-out}}.bDgIJb{display:flex;width:100%;flex-direction:column;align-items:center;justify-content:center}@media(min-width:768px){.bDgIJb{width:212px;flex-shrink:0;justify-content:flex-start;margin-left:24px;float:right}}.EYumw{display:none;flex-direction:row;align-items:center;justify-content:center;gap:8px;margin-top:8px}@media(min-width:768px){.EYumw{display:flex;margin-top:12px}}.kCOwPr{display:flex;width:100%;align-items:center;justify-content:center;gap:8px;margin-top:8px;margin-bottom:12px}@media(min-width:768px){.kCOwPr{display:none}}.iGXncB{display:flex;overflow:hidden;height:0;flex-direction:column;gap:8px;opacity:0;transition:all .3s ease-in-out}@media(min-width:768px){.iGXncB{display:flex;position:relative;width:auto;height:40px;order:-1;opacity:1;transition-behavior:allow-discrete}.iGXncB::after{--fade-from:rgba(253,232,234,0);--fade-to:#fde8ea;position:absolute;bottom:0;left:0;z-index:1;width:100%;height:40px;background-image:linear-gradient(to bottom,var(--fade-from),var(--fade-to));content:'';opacity:1;transition:opacity 150ms ease-out}}@media(min-width:768px){.doTReP{order:-1}}.ggPDxB{display:none;padding-top:8px;margin-top:16px;border-top:1px solid #919191}@media(max-width:767px){.ggPDxB{display:flex}}.gibhIT{display:none}@media(min-width:768px){.gibhIT{display:flex;position:relative;align-items:flex-start;margin-top:12px}}.dxwzhm{display:flex;min-height:600px;justify-content:center}@media(min-width:1000px){.dxwzhm{min-height:450px}}.gHNATZ{min-height:600px}@media(min-width:1000px){.gHNATZ{min-height:450px}}.gHNATZ.mobile-only{display:block}@media(min-width:1000px){.gHNATZ.mobile-only{display:none}}.gHNATZ.desktop-only{display:none}@media(min-width:1000px){.gHNATZ.desktop-only{display:block;margin-bottom:16px}}.gHNATZ.desktop-only+p{margin-top:0}.gHNATZ .third-party-ad{position:sticky;top:16px}.blOrrc{width:100%;flex-grow:1}.blOrrc .amp-article-content[amp-access][amp-access-hide]{display:block;overflow:hidden;max-height:360px}.blOrrc .amp-article-content[amp-access][amp-access-hide] .social-share{display:none}.blOrrc .amp-article-content[amp-access][amp-access-hide].show-all-content{max-height:100%}@media(max-width:594px){.blOrrc .amp-article-content[amp-access][amp-access-hide]{max-height:530px}}.blOrrc .amp-newsletter-reg-gate{position:relative;left:-12px;width:calc(100% + 24px)}.blOrrc .social-share{width:100%;padding-top:10px;padding-bottom:20px}@media(min-width:768px){.blOrrc .social-share{justify-content:flex-start}}.blOrrc .social-share.sticky{display:none}@media(min-width:1000px){.blOrrc .social-share.sticky{display:flex;position:sticky;top:14px;width:34px;flex-direction:column;margin-top:0;margin-left:-25%;float:left}.blOrrc .social-share.sticky amp-social-share,.blOrrc .social-share.sticky .sc-mgcah7-0{margin:0 0 16px}.article-feature-video .blOrrc .social-share.sticky{margin-top:0}.article-feature:not(.article-feature-video) .blOrrc .social-share.sticky{margin-top:35%}}.blOrrc.sponsored-article img,.blOrrc.sponsored-article video{width:100%;max-width:602px;height:auto}.blOrrc.sponsored-article iframe{max-width:602px;max-height:400px}.blOrrc .under-article-prompt-donations{padding-bottom:8px;margin-top:-3px}.blOrrc .big-letter{--color:#222;display:flex;position:relative;width:0;height:0;align-items:center;justify-content:center;padding:40px;margin-top:22px;margin-right:12px;border:1px solid var(--color);float:left;font:normal 52px/1 'Indy Serif','Indy Serif Fallback',serif;text-transform:uppercase}.blOrrc .big-letter:first-child{margin-top:6px}.blOrrc .big-letter::before{position:absolute;top:0;left:0;width:100%;height:100%;box-sizing:border-box;border:1px solid var(--color);border-radius:50%;content:''}.blOrrc #taboola-below-article-1{min-height:2350px}@media(min-width:768px){.blOrrc #taboola-below-article-1{min-height:3370px}}.blOrrc #taboola-below-article-1-split-num-1{min-height:130px}@media(min-width:768px){.blOrrc #taboola-below-article-1-split-num-1{min-height:415px}}.blOrrc .sc-fwko30-0+.sc-1xtsh2b-0{margin-top:-16px}@media(min-width:768px){.blOrrc{max-width:636px;margin:0}}@media(min-width:1000px){.blOrrc{max-width:624px;margin:0}.blOrrc.subscribed{max-width:636px}}@media(max-width:999px){.blOrrc{padding-right:0}.blOrrc .under-article-prompt-donations{margin-top:-18px}}.kvSKnI{display:flex;flex-wrap:wrap;justify-content:flex-start;margin-bottom:8px;color:#646464;font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.kvSKnI{width:70%;align-items:center;justify-content:flex-start;margin-bottom:0;font:normal 16px/24px 'Indy Sans','Indy Sans Fallback',sans-serif}}@media(min-width:1000px){.kvSKnI{width:70%;margin-bottom:0}}.fKGvbc{display:flex;height:20px;margin:0 12px 8px 0}.fKGvbc::before{display:inline-block;align-self:center;margin-top:1px;margin-right:12px;content:'\2022';transform:scale(1.5)}.fKGvbc:first-child::before{content:none}@media(min-width:768px){.fKGvbc{height:24px;margin-bottom:0}.fKGvbc::before{margin-top:2px}}.fKGvbc time{display:block}.fKGvbc time::first-letter {text-transform:capitalize}.eUdsoy{color:#fff}.jGlqRq{display:inline-block;margin:0 12px 8px 0;color:#ef4757;font:bold 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif;letter-spacing:-0.5px}.jGlqRq:hover,.jGlqRq:active{color:#f58992}@media(min-width:768px){.jGlqRq{margin-bottom:0}}.enHDwq{margin:0 4px 8px 0}.enHDwq::before{display:inline-block;margin-top:2px;margin-right:12px;color:#646464;content:'\2022';transform:scale(1.5)}.enHDwq:first-child::before{display:none}@media(min-width:768px){.enHDwq{margin-bottom:0}}.jmYqVV::before{color:#fff}.hfnwMY{display:flex;justify-content:flex-start;padding:0;margin:0 0 16px}@media(min-width:768px){.hfnwMY{display:flex;width:30%;align-items:center;justify-content:flex-end;margin:0}}@media(min-width:1000px){.hfnwMY{width:30%}}.hrDjjf{padding-top:0;border-top:0;border-bottom:0}@media(min-width:768px){.hrDjjf{display:flex;flex-flow:row wrap;padding-bottom:16px}.hrDjjf .sc-1qz44j0-0{order:1}.hrDjjf .sc-1qz44j0-10{order:2}}@media(min-width:1000px){.hrDjjf{flex-direction:row}}.dnLbAr{padding:16px 12px 12px;text-align:left;font:bold 14px/18px 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.dnLbAr{padding:16px 16px 12px}}.article-infact .dnLbAr{padding:16px 0}@media(min-width:1000px){.dnLbAr{padding:24px 0 19px}.article-feature .dnLbAr{max-width:968px;margin:0 auto}}.dnLbAr a{color:#fff}.dnLbAr a:hover{color:#f58992}.dnLbAr a:hover::after{color:#fff}.dnLbAr a::after{margin-right:4px;margin-left:4px;content:'>'}.dnLbAr a:last-child::after{display:none}.azcVx{margin:0 0 20px;letter-spacing:0}.VFZbw{margin:0;color:#646464;font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.VFZbw{font:normal 18px/22px 'Indy Sans','Indy Sans Fallback',sans-serif}}@media(min-width:1000px){.VFZbw{font:normal 20px/24px 'Indy Sans','Indy Sans Fallback',sans-serif}}.VFZbw p{font:inherit}.article-feature .VFZbw a{font-weight:bold}.hsJCLD{max-width:968px;margin:0 auto;background:#222}@media(min-width:1000px){.hsJCLD{padding:0 16px}.parallax .hsJCLD{max-width:1240px}}.bJjAgi{font:bold 32px/36px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.0156em}@media(min-width:768px){.bJjAgi{font:bold 44px/48px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.0113em}}@media(min-width:1000px){.bJjAgi{font:bold 54px/58px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.0092em}}.hZFQIi{background:#222}.hZFQIi .sc-qvufca-1{max-width:968px;background:#222}.hZFQIi .sc-qvufca-0{margin:0}@media(max-width:999px){.hZFQIi .sc-qvufca-0{margin:0 12px 0}}.hZFQIi .sc-22qwnu-0,.hZFQIi .sc-22qwnu-0 a{color:#fff}.hZFQIi .sc-qvufca-2,.hZFQIi .sc-aeekvc-0{color:#fff}.hZFQIi .sc-qvufca-2{margin:0 0 20px}.hZFQIi .sc-aeekvc-0{margin-bottom:16px}@keyframes slidedown-video{from{transform:translateY(-100%)}to{transform:translateY(0)}}@keyframes slideup-video{from{transform:translateY(200%)}to{transform:translateY(0)}}.ghXxSp .video-top-container-inner{position:relative}.ghXxSp .video-popout-close{display:none}.ghXxSp .video-hero-wrapper-inner{display:block}.ghXxSp .video-hero-video{width:100%;margin:0;transition:height .2s}.ghXxSp .video-hero-wrapper.sticky-video{position:fixed;top:95px;width:400px;margin-left:-332px;transition:margin-left .3s,top .3s .1s}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video{position:static;right:0;left:auto;width:100%}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video.liveblog{margin-left:-12px}@media(min-width:768px){.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video{position:absolute;width:400px}}@media(min-width:1000px){.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video{top:94px;right:-56px}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video.liveblog{right:-400px}}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video .video-sticky-video{position:fixed;top:0;left:auto;z-index:9;width:100%;background-color:#fff;box-shadow:0 0 40px 10px rgba(0,0,0,0.5)}@media(min-width:768px){.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video .video-sticky-video{width:400px;animation:slidedown-video .4s}}@media(min-width:1000px){.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video .video-sticky-video{top:auto;bottom:0;animation:slideup-video .4s}}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-popout-close{display:none;width:100%;box-sizing:border-box;align-items:center;justify-content:flex-end;padding:4px 8px 3px;color:#222;cursor:pointer;font-family:'Indy Sans','Indy Sans Fallback',sans-serif;font-size:14px;line-height:14px}@media(min-width:1000px){.ghXxSp .video-top-container.video.sticky:not(.closed) .video-popout-close{justify-content:flex-start}}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-popout-close::after{display:flex;align-items:center;padding-left:4px;content:'\2715';font-size:12px}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-popout-close.shown{display:flex}.rdSkV{max-width:100%}.DduFK{position:relative}.hBOwuD{position:relative;width:100%;padding-top:56.25%;background:#000}.fSyNsa{display:flex;position:absolute;top:0;left:0;width:100%;height:100%;align-items:center;justify-content:center}.cZXjIc{width:10%}.bFEGho.fullscreen{position:fixed;top:0;left:0;z-index:3000000000;width:100%;height:100%;background:#000}.bFEGho .closebtn{display:none;position:absolute;top:0;right:0;width:100px;height:100px}.bFEGho .closebtn.show{display:block}.bFEGho .btn{position:absolute;top:5px;right:5px;width:25px;height:25px;color:#fff;font-family:helvetica,sans-serif;font-size:20px;line-height:25px;text-align:center}.JCJLP{max-width:100%;clear:both}.dyGKzS{--bleed:12px;display:flex;box-sizing:border-box;flex-direction:row;gap:32px;padding:16px var(--bleed);background-color:#fff}.article-liveblog .dyGKzS{background-color:#f7f7f7}@media(min-width:768px){.dyGKzS{--bleed:0;max-width:1000px;margin:0 auto}}@media(min-width:1000px){.dyGKzS{--bleed:16px;max-width:1000px;padding:var(--bleed)}}.gIldS{overflow:hidden;height:0;color:transparent}.kFPmfF{max-width:100%;margin:0 0 20px}.kFPmfF.sticky{position:sticky;top:16px}.iaRZct{min-height:600px}.iaRZct #mpu1{position:sticky;top:16px}.bFiDnI{min-height:250px}.jAzEot{max-width:100%}.eDScvc{margin:0 0 6px;color:#646464;font-family:'Indy Sans','Indy Sans Fallback',sans-serif;font-size:15px}.CmSgF{margin:0 0 12px}.lbFVDq{height:380px}.bsSHYO{width:100%;height:51px}.bjKtIv{margin-bottom:16px;border-bottom:1px solid #919191}.jLzsCV{margin-bottom:16px}.jLzsCV [role='listitem']{position:relative;margin-bottom:12px;border-bottom:1px solid #d3d3d3}.jLzsCV [role='listitem'] .sc-u4n1j-0{display:flex;position:absolute;bottom:16px;left:10px;width:32px;height:32px;align-items:center;justify-content:center;border-radius:50%;background-color:#ec1a2e}.jLzsCV [role='listitem'] .sc-u4n1j-0>svg{width:90%;fill:#fff;stroke:transparent}.jLzsCV [role='listitem']:first-child{display:block;padding-bottom:0;margin-bottom:12px}.jLzsCV [role='listitem']:first-child .sc-u4n1j-0{top:-15px;bottom:auto;left:12px;width:35px;height:35px}.jLzsCV [role='listitem']:first-child>*:first-child{display:block;width:100%;height:205px}.jLzsCV [role='listitem']:first-child>*:last-child{position:absolute;bottom:0;width:100%;padding:28px 12px 12px;background:linear-gradient(to top,#222 50%,rgba(34,34,34,0.9) 100%) no-repeat;color:#fff;font-size:17px;font-weight:bold}.jLzsCV [role='listitem']:last-child{margin-bottom:0;border-bottom:0 none}@media(max-width:767px){.eKzHlQ{display:none}}.iFeFcz{width:308px}.iFeFcz.hidden{display:none}@media(max-width:999px){.iFeFcz{display:none}}.article-liveblog .fbWdwj{background-color:#f7f7f7}.eFgmkR{justify-content:center}.cvujVr{justify-content:center}
Lifestyle Health & Families Life-extending drug to be offered to advanced prostate cancer patients by NHS in England Darolutamide will be available to eligible patients ‘within weeks’
Kate Ng Monday 28 November 2022 08:37 GMT
Subscribe to Independent Premium to bookmark this article Want to bookmark your favourite articles and stories to read or reference later? Start your Independent Premium subscription today.
Subscribe Already subscribed? Log in Jools Holland speaks out about prostate cancer diagnosis for the first time Your support helps us to tell the story From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or producing our latest documentary, 'The A Word', which shines a light on the American women fighting for reproductive rights, we know how important it is to parse out the facts from the messaging.
At such a critical moment in US history, we need reporters on the ground. Your donation allows us to keep sending journalists to speak to both sides of the story.
The Independent is trusted by Americans across the entire political spectrum. And unlike many other quality news outlets, we choose not to lock Americans out of our reporting and analysis with paywalls. We believe quality journalism should be available to everyone, paid for by those who can afford it.
Your support makes all the difference. Close Read more A new treatment will be offered to prostate cancer patients whose disease has spread to other parts of the body to give them a better chance of living longer.
The NHS in England will become the first healthcare provider in Europe to offer the drug darolutamide to around 9,000 men who are eligible.
Studies have shown that patients who were previously left untreated saw their chances of living longer increase by one-third after using darolutamide, which is known by its brand name, Nuqeba.
It works by blocking androgen receptors in cancer cells. This, in turn, blocks the effect of testosterone that allows cancer cells to multiply.
The health service in England is able to offer the drug thanks to a fast-tracked approval of darolutamide by the UK’s Medicines and Healthcare products Healthcare products Regulatory Agency (MHRA) through Project Orbis.
Project Orbis is an international partnership between medicines regulators in the UK, US, Australia and other countries. It was set up to speed up the approval process for cancer treatments that have promising results, according to the NHS.
NHS executive Amanda Pritchard said: “It is fantastic that patients in England will be the first in Europe to receive this treatment for a really advanced and aggressive form of prostate cancer thanks to the NHS fast tracking a new drug deal.
“The NHS is continuing to lead the way in securing the best possible treatments for patients – this is the latest in a long list of cutting-edge drugs that we have secured to help people to live longer with cancer, making a huge, life-changing difference to patients and their families across the country.”
Prostate cancer is the most common cancer in men, with around 47,000 people diagnosed with it annually in England. Almost 9,000 people will suffer the more aggressive form of metastatic prostate cancer.
The drug comes in a tablet form and should be taken with food. Combined with androgen-deprived therapy (ADT) and chemotherapy, a trial showed that patients were 32.5 per cent less likely to die than if they underwent ADT and chemotherapy alone.
The trial was carried out across almost 300 sites around the world, including several NHS hospitals.
Professor Peter Johnson, the NHS national director for cancer, added that the treatment “builds on the NHS ambition to improve cancer care and survival rate”.
“We know that prostate cancer is the most common form of cancer among men and it is vital the NHS continues to diagnose patients as early as possible and expand our arsenal of cutting-edge treatments in order to increase the chances of people surviving.”
The NHS said it will start offering the new drug to eligible prostate cancer patients “within weeks”.
Thank you for registering Please refresh the page or navigate to another page on the site to be automatically logged in Please refresh your browser to be logged in
Join our commenting forum
Join thought-provoking conversations, follow other Independent readers and see their replies
Comments