Body tells sunburnt cells: commit suicide
SCIENTISTS HAVE discovered a key step in how the body prevents sunburn from automatically causing skin cancer - it forces cells damaged by the sun to commit suicide.
Scientists at the University of Texas in Houston shone ultraviolet light at two groups of shaved mice, one of which lacked a particular protein that is thought to be linked to cell suicide. Seventy per cent of the protein-deficient mice accumulated potentially cancerous cell mutations in their skin, compared with 5 per cent of themice which had the protein, according to results published today in Science.
The researchers said the results suggest that molecular interactions involving the cell-suicide protein were "pivotal" in the pathway to the growth and spread of sunlight-induced skin tumours.
Dr Tony Quinn, from the Imperial Cancer Research Fund's skin tumour laboratory at St Bartholomew's Hospital in London, said: "What the research suggests is that if this pathway is disturbed it may be a way that [skin] cancer can occur. It could explain why some people in the population are more at risk from [exposure to] sunlight."
Subscribe to Independent Premium to bookmark this article
Want to bookmark your favourite articles and stories to read or reference later? Start your Independent Premium subscription today.
Join our commenting forum
Join thought-provoking conversations, follow other Independent readers and see their replies