Ryan James, the vet jailed for life at Stafford Crown Court last May for poisoning his wife, has lost his appeal against conviction. James, 41, a partner in a practice at Burton upon Trent, Staffordshire, was alleged to have killed Sandra, 39, by lacing her orange juice with Immobilon, a drug used to immobilise horses, so he could collect her pounds 180,000 life insurance and start a new life with his mistress, Catherine Crooks. James married Mrs Crooks at Gartree top security jail, Leicestershire, last September.
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