") no-repeat center center;background-size:10px 16px;content:' '}@media(min-width:768px){.UeJNJ::before{display:none}}.cPCVUJ{min-height:389px;margin-bottom:16px;clear:both}@media(min-width:1000px){.cPCVUJ{min-height:380px}}.gSkBXd{aspect-ratio:16/9}.rAFIl{width:100%;box-sizing:border-box}@media(min-width:768px){.rAFIl{max-width:634px}}@media(min-width:1250px){.rAFIl{max-width:622px}}.dLkuvY{display:flex;width:auto;box-sizing:border-box;align-items:center;justify-content:flex-start;gap:4px;color:#ec1a2e;color:light-dark(#ec1a2e,#ec1a2e)}.jrwZqm{display:block;font:bold 14px/20px 'Indy Sans','Indy Sans Fallback',sans-serif;text-decoration-line:underline;margin-block:0;text-align:center}.dHXFkr{display:inline-flex;align-items:center;justify-content:center;gap:4px}.dHXFkr:hover .sc-aja53j-2,.dHXFkr:hover .sc-a5wy94-0{color:#ac2a2c;color:light-dark(#ac2a2c,#f58992)}.lcJUSj{font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}.hJPJVF{display:flex;position:relative;overflow:hidden;width:auto;height:40px;flex-direction:column;order:-1;gap:8px;opacity:1;transition:all .5s ease-in-out;transition-behavior:allow-discrete}.hJPJVF::after{--fade-from:rgba(255,255,255,0);--fade-mid:rgba(255,255,255,0.5);--fade-to:#fff;position:absolute;bottom:0;left:0;z-index:1;width:100%;height:40px;background-image:linear-gradient(to bottom,var(--fade-from) 0,var(--fade-mid) 50%,var(--fade-to) 100%);content:'';opacity:1;pointer-events:none;transition:opacity 150ms ease-out}@supports(color:light-dark(red,red)){.hJPJVF::after{--fade-from:light-dark(rgba(255,255,255,0),rgba(0,0,0,0))}}@supports(color:light-dark(red,red)){.hJPJVF::after{--fade-mid:light-dark(rgba(255,255,255,0.5),rgba(0,0,0,0.5))}}@supports(color:light-dark(red,red)){.hJPJVF::after{--fade-to:light-dark(#fff,#000)}}@media(min-width:768px){.PdmgT{order:-1}}@media(min-width:768px){.eMEmGu{display:flex;position:relative;align-items:flex-start;margin-top:12px}}@media(min-width:1000px){.lfyduH .taboola{display:none}}.lfyduH:has(#taboola-carousel-thumbnails){min-height:426px}.lfyduH:has(#taboola-mid-article-thumbnails-crime){min-height:405px}@media(min-width:1000px){.lfyduH:has(#taboola-carousel-thumbnails),.lfyduH:has(#taboola-mid-article-thumbnails-crime){min-height:0}}.iUtUOL .tp-container-inner,.iUtUOL .sc-1suqprf-0{position:relative;box-shadow:0 -22px 16px 22px rgba(255,255,255,0.95);box-shadow:0 -22px 16px 22px light-dark(rgba(255,255,255,0.95),rgba(0,0,0,0.95))}.iUtUOL.closed{display:none}.dOsHXs{display:block;margin:0 0 16px;color:inherit;text-decoration:underline}.cAWJSb{width:32px}.cAWJSb,.cAWJSb:focus{color:#627aac;color:light-dark(#627aac,#627aac)}.cAWJSb:hover,.cAWJSb:active,.cAWJSb:focus-visible{color:#9cabcb;color:light-dark(#9cabcb,#9cabcb)}@media(min-width:768px){.cAWJSb.mobile-only{display:none}}.kvSIBL{width:32px}.kvSIBL,.kvSIBL:focus{color:#4e4e4e;color:light-dark(#4e4e4e,#4e4e4e)}.kvSIBL:hover,.kvSIBL:active,.kvSIBL:focus-visible{color:#919191;color:light-dark(#919191,#919191)}@media(min-width:768px){.kvSIBL.mobile-only{display:none}}.fAfNYP{width:32px}.fAfNYP,.fAfNYP:focus{color:#25d366;color:light-dark(#25d366,#25d366)}.fAfNYP:hover,.fAfNYP:active,.fAfNYP:focus-visible{color:#66e093;color:light-dark(#66e093,#66e093)}@media(min-width:768px){.fAfNYP.mobile-only{display:none}}.jOXOdf{width:32px}.jOXOdf,.jOXOdf:focus{color:#ec1a2e;color:light-dark(#ec1a2e,#ec1a2e)}.jOXOdf:hover,.jOXOdf:active,.jOXOdf:focus-visible{color:#f58992;color:light-dark(#f58992,#f58992)}@media(min-width:768px){.jOXOdf.mobile-only{display:none}}.dzqQwN{display:flex;gap:12px}.dFzDMM .sc-17yxc4y-0{display:none}.dFzDMM:hover .sc-17yxc4y-0,.dFzDMM.bookmark-button-saved .sc-17yxc4y-0{display:block}.dFzDMM:hover .sc-17yxc4y-1,.dFzDMM.bookmark-button-saved .sc-17yxc4y-1{display:none}.dFzDMM.bookmark-button-saved .sc-17yxc4y-0{display:block}.dFzDMM.bookmark-button-saved .sc-17yxc4y-1{display:none}.dFzDMM.bookmark-button-saved:hover .sc-17yxc4y-0{display:none}.dFzDMM.bookmark-button-saved:hover .sc-17yxc4y-1{display:block}.iJqvPe{display:inline-block;width:32px;height:32px;color:#70a5a7;color:light-dark(#70a5a7,#70a5a7)}.sQzGY{display:flex;flex-direction:row;justify-content:center;gap:12px}.cNueyK{display:flex;position:relative;justify-content:center}@media(min-width:768px){.cNueyK{justify-content:flex-end;padding-top:12px;margin:0}}.dUmHef{display:flex}.sticky .dUmHef{flex-direction:column}.igSthU{overflow:hidden;height:23px;margin-bottom:8px;border-bottom:0;clear:both}@media(min-width:768px){.igSthU{height:25px}}.fvIzys{display:inline-block;flex-shrink:0;margin:0 12px 0 0;font:bold 14px/normal 'Indy Sans','Indy Sans Fallback',sans-serif}.fvIzys::after{content:':'}.knjHva{display:inline-block;margin-right:12px;margin-bottom:4px;color:#222;color:light-dark(#222,#fff);font:normal 14px/1.29 'Indy Sans','Indy Sans Fallback',sans-serif;text-decoration:underline}.knjHva::first-letter {text-transform:capitalize}@media(min-width:1000px){.subscribed .gryCYY{margin-top:-184px}.article-feature:not(.article-feature-video) .subscribed .gryCYY{margin-top:-407px}}.gryCYY>p{margin:16px 0}.article-premium .gryCYY>p{line-height:27px}.gryCYY>h2{font-size:21px}.article-climate .gryCYY>h2{color:#ec1a2e;color:light-dark(#ec1a2e,#ec1a2e)}.article-sgi .gryCYY>h2{color:#ec1a2e;color:light-dark(#ec1a2e,#ec1a2e)}.gryCYY>p:first-child{margin-top:0}.gryCYY span:first-child~p:first-of-type{margin-top:0}.FtcnY{display:flex;position:relative;max-width:100%;min-height:600px;justify-content:center;margin:0 auto;background-color:transparent;clear:both}@media(min-width:1000px){.FtcnY{min-height:450px}}.teads .FtcnY{display:block}.FtcnY [data-mpu]{position:sticky;top:16px}@media(min-width:1000px){.cCcguK{display:none}}.cCcguK[data-mpu1]{min-height:600px}.cCcguK.pb-20{padding-bottom:20px}.dFpFuY{overflow:hidden;width:100%;box-sizing:border-box;margin-bottom:16px}@media(min-width:768px){.dFpFuY{max-width:634px}}@media(min-width:1250px){.dFpFuY{max-width:622px}}.dmMyEN{width:100%;box-sizing:border-box;padding:8px 12px 12px;border-top:8px solid #ec1a2e;border-top:8px solid light-dark(#ec1a2e,#ec1a2e);background-color:#fde8ea;background-color:light-dark(#fde8ea,#66000a)}@media(min-width:768px){.dmMyEN{padding-top:4px;padding-bottom:12px}}.fXvmgM{font:bold 22px/26px 'Indy Serif','Indy Serif Fallback',serif;margin:0 0 12px;text-align:center}@media(min-width:768px){.fXvmgM{font:bold 30px/34px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.048px;margin-bottom:12px;text-align:left}}.ivTlwT{display:block;margin-bottom:12px}@media(min-width:768px){.ivTlwT{display:none}}.hfMbpT{display:flex;width:100%;box-sizing:border-box;align-items:center;justify-content:center;gap:4px;background-color:#fde8ea;background-color:light-dark(#fde8ea,#66000a);color:#ec1a2e;color:light-dark(#ec1a2e,#ec1a2e)}@media(min-width:768px){.hfMbpT{width:auto;justify-content:flex-start}}.dAuNha{display:block;font:bold 14px/20px 'Indy Sans','Indy Sans Fallback',sans-serif;text-decoration-line:underline;margin-block:0;text-align:center}.jiDyot{display:inline-flex;align-items:center;justify-content:center;gap:4px}.jiDyot:hover .sc-hez36s-5,.jiDyot:hover .sc-a5wy94-0{color:#ac2a2c;color:light-dark(#ac2a2c,#f58992)}.laZbyn{font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}.juUDRT{display:flex;width:100%;flex-direction:column}@media(min-width:768px){.juUDRT{display:flow-root;gap:24px;transition:margin-bottom .3s ease-in-out}}.kRWakq{display:flex;width:100%;flex-direction:column;align-items:center;justify-content:center}@media(min-width:768px){.kRWakq{position:relative;z-index:1;width:212px;flex-shrink:0;justify-content:flex-start;margin-left:24px;float:right}}.eJjJXF{display:none;flex-direction:row;align-items:center;justify-content:center;gap:8px;margin-top:8px}@media(min-width:768px){.eJjJXF{display:flex;margin-top:12px}}.dLfZIO{display:flex;width:100%;align-items:center;justify-content:center;gap:8px;margin-top:8px;margin-bottom:12px}@media(min-width:768px){.dLfZIO{display:none}}@media(min-width:768px){.cqPbFA{order:-1}}.jZSKtc .sc-aja53j-5::after{--fade-from:rgba(253,232,234,0);--fade-mid:rgba(253,232,234,0.5);--fade-to:#fde8ea}@media(min-width:360px){.jZSKtc .sc-aja53j-5 .sc-aja53j-7{display:none}}@supports(color:light-dark(red,red)){.jZSKtc .sc-aja53j-5::after{--fade-from:light-dark(rgba(253,232,234,0),rgba(102,0,10,0))}}@supports(color:light-dark(red,red)){.jZSKtc .sc-aja53j-5::after{--fade-mid:light-dark(rgba(253,232,234,0.5),rgba(102,0,10,0.5))}}@supports(color:light-dark(red,red)){.jZSKtc .sc-aja53j-5::after{--fade-to:light-dark(#fde8ea,#66000a)}}.cKWiEj{margin:0 0 24px;font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}.huxBsk{font:bold 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}.jaiOuh{display:flex;min-height:600px;justify-content:center}@media(min-width:1000px){.jaiOuh{min-height:450px}}.jasvOK{min-height:600px}@media(min-width:1000px){.jasvOK{min-height:450px}}.jasvOK.mobile-only{display:block}@media(min-width:1000px){.jasvOK.mobile-only{display:none}}.jasvOK.desktop-only{display:none}@media(min-width:1000px){.jasvOK.desktop-only{display:block;margin-bottom:16px}}.jasvOK.desktop-only+p{margin-top:0}.jasvOK .third-party-ad{position:sticky;top:16px}.bYBoJE{width:100%;flex-grow:1}.bYBoJE .social-share{width:100%;padding-top:10px;padding-bottom:20px}@media(min-width:768px){.bYBoJE .social-share{justify-content:flex-start}}.bYBoJE .social-share.sticky{display:none}@media(min-width:1000px){.bYBoJE .social-share.sticky{display:flex;position:sticky;top:14px;width:34px;flex-direction:column;padding-top:0;margin-top:0;margin-left:-25%}.bYBoJE .social-share.sticky .sc-mgcah7-0{margin:0 0 16px}.article-feature-video .bYBoJE .social-share.sticky{margin-top:0}.article-feature:not(.article-feature-video) .bYBoJE .social-share.sticky{margin-top:35%}}.bYBoJE.sponsored-article img,.bYBoJE.sponsored-article video{width:100%;max-width:602px;height:auto}.bYBoJE.sponsored-article iframe{max-width:602px;max-height:400px}.bYBoJE .under-article-prompt-donations{padding-bottom:8px;margin-top:-3px}.bYBoJE .big-letter{--color:#222;display:flex;position:relative;width:0;height:0;align-items:center;justify-content:center;padding:40px;margin-top:22px;margin-right:12px;border:1px solid var(--color);float:left;font:normal 52px/1 'Indy Serif','Indy Serif Fallback',serif;text-transform:uppercase}.bYBoJE .big-letter:first-child{margin-top:6px}.bYBoJE .big-letter::before{position:absolute;top:0;left:0;width:100%;height:100%;box-sizing:border-box;border:1px solid var(--color);border-radius:50%;content:''}.bYBoJE #taboola-below-article-1{min-height:2350px}@media(min-width:768px){.bYBoJE #taboola-below-article-1{min-height:3370px}}.bYBoJE #taboola-below-article-1-split-num-1{min-height:130px}@media(min-width:768px){.bYBoJE #taboola-below-article-1-split-num-1{min-height:415px}}.bYBoJE .sc-fwko30-0+.sc-1xtsh2b-0{margin-top:-16px}@media(min-width:768px){.bYBoJE{max-width:636px;margin:0}}@media(min-width:1000px){.bYBoJE{max-width:624px;margin:0}.bYBoJE.subscribed{max-width:636px}}@media(max-width:999px){.bYBoJE{padding-right:0}.bYBoJE .under-article-prompt-donations{margin-top:-18px}}.bYBoJE .anchor-nav-header{scroll-margin-top:79px}.bYBoJE .anchor-nav-header a{color:#222;color:light-dark(#222,#fff)}.bYBoJE .anchor-nav-header a:hover{color:#222;color:light-dark(#222,#fff)}@supports(color:light-dark(red,red)){.bYBoJE .big-letter{--color:light-dark(#222,#fff)}}.liYrJc{display:flex;flex-wrap:wrap;justify-content:flex-start;margin-bottom:8px;color:#d3d3d3;color:light-dark(#d3d3d3,#d3d3d3);font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.liYrJc{width:70%;align-items:center;justify-content:flex-start;margin-bottom:0;font:normal 16px/24px 'Indy Sans','Indy Sans Fallback',sans-serif}}@media(min-width:1000px){.liYrJc{width:70%;margin-bottom:0}}.dMNxBE{display:flex;height:20px;margin:0 12px 8px 0}.article-voices .dMNxBE{height:auto}@media(min-width:425px){.article-voices .dMNxBE{height:20px}}.dMNxBE::before{display:inline-block;align-self:center;margin-top:1px;margin-right:12px;content:'\2022';transform:scale(1.5)}.dMNxBE:first-child::before{content:none}@media(min-width:768px){.dMNxBE{height:24px;margin-bottom:0}.dMNxBE::before{margin-top:2px}}.dMNxBE time{display:block}.dMNxBE time::first-letter {text-transform:capitalize}.efpEY{display:inline-block;margin:0 12px 8px 0;color:#ef4757;color:light-dark(#ef4757,#ef4757);font:bold 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif;letter-spacing:-0.5px}.efpEY:hover,.efpEY:active{color:#f58992;color:light-dark(#f58992,#f58992)}@media(min-width:768px){.efpEY{margin-bottom:0}}.ePBJFt{margin:0 12px 8px -8px}@media(min-width:768px){.ePBJFt{margin-bottom:0}}.fefQOD{margin:0 4px 8px 0}.fefQOD::before{display:inline-block;margin-top:2px;margin-right:12px;color:#d3d3d3;color:light-dark(#d3d3d3,#d3d3d3);content:'\2022';transform:scale(1.5)}.fefQOD:first-child::before{display:none}@media(min-width:768px){.fefQOD{margin-bottom:0}}.bMRmfY{display:flex;justify-content:flex-start;padding:0;margin:0 0 16px}@media(min-width:768px){.bMRmfY{display:flex;width:30%;align-items:center;justify-content:flex-end;margin:0}}@media(min-width:1000px){.bMRmfY{width:30%}}.dfBarH{padding-top:0;border-top:0;border-bottom:0}@media(min-width:768px){.dfBarH{display:flex;flex-flow:row wrap;padding-bottom:16px}.dfBarH .sc-mzrbq8-0{order:1}.dfBarH .sc-mzrbq8-6{order:2}}@media(min-width:1000px){.dfBarH{flex-direction:row}}.gkrVhQ{padding:16px 12px 12px;text-align:left;font:bold 14px/18px 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.gkrVhQ{padding:16px 16px 12px}}.article-infact .gkrVhQ{padding:16px 0}@media(min-width:1000px){.gkrVhQ{padding:24px 0 19px}.article-feature .gkrVhQ{max-width:968px;margin:0 auto}}.gkrVhQ a{color:#fff;color:light-dark(#fff,#fff)}.gkrVhQ a:hover{color:#f58992;color:light-dark(#f58992,#f58992)}.gkrVhQ a:hover::after{color:#fff;color:light-dark(#fff,#fff)}.gkrVhQ a::after{margin-right:4px;margin-left:4px;content:'>'}.gkrVhQ a:last-child::after{display:none}.gbPKFW{margin:0 0 20px;letter-spacing:0}.bulCXp{margin:0;color:#d3d3d3;color:light-dark(#d3d3d3,#d3d3d3);font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.bulCXp{font:normal 18px/22px 'Indy Sans','Indy Sans Fallback',sans-serif}}@media(min-width:1000px){.bulCXp{font:normal 20px/24px 'Indy Sans','Indy Sans Fallback',sans-serif}}.bulCXp p{font:inherit}.article-feature .bulCXp a{font-weight:bold}.gOoYlj{max-width:968px;margin:0 auto;background:#222;background:light-dark(#222,#222)}@media(min-width:1000px){.parallax .gOoYlj{max-width:1240px}}.fdtMsm{font:bold 32px/36px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.0156em}@media(min-width:768px){.fdtMsm{font:bold 44px/48px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.0113em}}@media(min-width:1000px){.fdtMsm{font:bold 54px/58px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.0092em}}.cuYuhQ{background:#222;background:light-dark(#222,#222)}.cuYuhQ .sc-qvufca-1{max-width:968px;background:#222;background:light-dark(#222,#222)}.cuYuhQ .sc-qvufca-0{margin:0}@media(max-width:999px){.cuYuhQ .sc-qvufca-0{margin:0 12px 0}}.cuYuhQ .sc-qvufca-2,.cuYuhQ .sc-1cmj4ml-0{color:#fff;color:light-dark(#fff,#fff)}.cuYuhQ .sc-qvufca-2{margin:0 0 20px}.cuYuhQ .sc-1cmj4ml-0{margin-bottom:16px}.eBMXOi{max-width:100%;clear:both}@media(min-width:1000px){.kFNaRc .sc-qvufca-1{padding:0 16px}}.fzuCgM{overflow:hidden;height:0;color:transparent}.fmcHss{max-width:100%;margin:0 0 20px}.fmcHss.sticky{position:sticky;top:16px}.hlxBlR{min-height:600px}.hlxBlR #mpu1,.hlxBlR #sidebar1{position:sticky;top:16px}.MxpAk{min-height:250px}.clQXMC{max-width:100%}.eEtnsS{margin:0 0 6px;color:#646464;color:light-dark(#646464,#bdbdbd);font-family:'Indy Sans','Indy Sans Fallback',sans-serif;font-size:15px}.PbXHI{margin:0 0 12px}.hVucHy{height:380px}.pAheK{width:100%;height:51px}.lgmjvx{margin-bottom:16px;border-bottom:1px solid #919191;border-bottom:1px solid light-dark(#919191,#646464)}.gSAEA-d{margin-bottom:16px}.gSAEA-d [role='listitem']{position:relative;margin-bottom:12px;border-bottom:1px solid #d3d3d3;border-bottom:1px solid light-dark(#d3d3d3,#919191)}.gSAEA-d [role='listitem'] .sc-u4n1j-0{display:flex;position:absolute;bottom:16px;left:10px;width:32px;height:32px;align-items:center;justify-content:center;border-radius:50%;background-color:#ec1a2e;background-color:light-dark(#ec1a2e,#ec1a2e)}.gSAEA-d [role='listitem'] .sc-u4n1j-0>svg{width:90%;fill:#fff;fill:light-dark(#fff,#000);stroke:transparent}.gSAEA-d [role='listitem']:first-child{display:block;padding-bottom:0;margin-bottom:12px}.gSAEA-d [role='listitem']:first-child .sc-u4n1j-0{top:-15px;bottom:auto;left:12px}.gSAEA-d [role='listitem']:first-child>*:first-child{display:block;width:100%;height:205px}.gSAEA-d [role='listitem']:first-child>*:last-child{--content-bg:#222;--content-bg-opaque:rgba(34,34,34,0.7);position:absolute;bottom:0;width:100%;padding:28px 12px 12px;background:linear-gradient(to top,var(--content-bg) 70%,var(--content-bg-opaque) 100%) no-repeat;color:#fff;color:light-dark(#fff,#222);font-size:17px;font-weight:bold}.gSAEA-d [role='listitem']:last-child{margin-bottom:0;border-bottom:0 none}@supports(color:light-dark(red,red)){.gSAEA-d [role='listitem']:first-child>*:last-child{--content-bg:light-dark(#222,#222)}}@supports(color:light-dark(red,red)){.gSAEA-d [role='listitem']:first-child>*:last-child{--content-bg-opaque:light-dark(rgba(34,34,34,0.7),rgba(34,34,34,0.7))}}.fgtiQY{min-height:1924px}@media(max-width:767px){.fgtiQY{display:none}}.eqQkhO{width:308px;height:100%;margin-left:auto}.eqQkhO.hidden{display:none}@media(max-width:999px){.eqQkhO{display:none}}.article-liveblog .dzfINj{background-color:#f7f7f7;background-color:light-dark(#f7f7f7,#222)}.jBkNwU{justify-content:center}.cumEve{justify-content:center}@keyframes hqVOOe1548920386{from{transform:translateX(0)}to{transform:translateX(-100%)}}@keyframes bReFEb1548920386{from{transform:translateX(100%)}to{transform:translateX(0)}}
Stay up to date with notifications from The Independent Notifications can be managed in browser preferences.
Not now Yes please
News World Americas US doctors trialling brain surgery to stop opioid addiction As deaths from drug overdoses surge, doctors hope a groundbreaking new brain surgery could help addicts who have exhausted all forms of rehabilitation
Opioid addicts receiving life-saving surgery Leer en Español Your support helps us to tell the story From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or producing our latest documentary, 'The A Word', which shines a light on the American women fighting for reproductive rights, we know how important it is to parse out the facts from the messaging.
At such a critical moment in US history, we need reporters on the ground. Your donation allows us to keep sending journalists to speak to both sides of the story.
The Independent is trusted by Americans across the entire political spectrum. And unlike many other quality news outlets, we choose not to lock Americans out of our reporting and analysis with paywalls. We believe quality journalism should be available to everyone, paid for by those who can afford it.
Your support makes all the difference. Read more Doctors in West Virginia are trialling an experimental brain surgery on chronic opioid addicts that they hope will rewire patients’ neural reward systems.
The surgery is part of a clinical trial run by West Virginia University’s Rockefeller Neuroscience Institute, and involves implanting tiny electrodes that send electrical pulses to the part of the brain that rewards pleasure-seeking behaviours.
Doctors hope the study will help to drown out cravings, offering a way out of long-term addiction for patients who have exhausted other rehabilitation methods and suffered multiple overdoses.
The method is known as deep brain stimulation (DBS) and has previously been used to successfully treat the symptoms of Parkinson’s Disease, by changing the way the brain’s reward centre works.
James Fisher told NBC Nightly News with Lester Holt he was desperate to take part in the study after suffering four near-fatal drug overdoses.
Mr Fisher said he had been using drugs since his teenage years, and became addicted to benzodiazepine or “benzos”.
He found it easy to get prescriptions for a time, and when that dried up he was forced to buy from friends, and began stealing to pay for his habit.
“I don’t want to die,” Mr Fisher told NBC Nightly News with Lester Holt prior to his surgery in July.
“I don’t want to live that miserable life of being sober and still wanting something and not being able to get it.”
Since his surgery, Mr Fisher said he no longer felt depressed or anxious, and no longer craved drugs. He told NBC News he had been clean for two months.
“It’s like night and day,” he said.
According to the National Institute on Drug Abuse , the brain reward system is a brain circuit that causes feelings of pleasurewhen it’s “turned on” by something an enjoyable activity, such as eating good food or sex.
Whenever this reward circuit is activated, our brains note that something important is happening that’s worth remembering and repeating.
Drugs such as opioids and benzodiazepine hijack the reward system, causing addicts to crave larger quantities to satisfy them.
The Rockefeller Neuroscience Institute’s executive chair Dr Ali Rezai told NBC News deep brain stimulation had been used successfully to treat the symptoms of Parkinson’s disease for decades.
Doctors at the institute began developing a similar technique to treat addicts who were beyond the help of other treatments.
“Our hypothesis was that by using the DBS in this part of the brain, we would essentially be normalizing the dopamine levels,” Dr Rezai said.
“In addiction, the rewards part of the brain releases dopamine when the drug is taken and people feel good. And then they want more next time to get to the same feeling.”
The trial began in 2019, and Mr Fisher was only the third patient to undergo the surgery.
Doctors are planning a second phase involving 10 patients who have tried everything else to get off opioids.
The need for innovative treatments is acute, with more than 93,000 Americans dying of drug overdoses in 2020 , according to the Centers for Disease Control and Prevention. Synthetic opioids accounted for 60 per cent of deaths.
The coronavirus pandemic has been blamed on the soaring drug overdose figures, with a nearly 50 per cent spike in fatalities since 2018.
Thank you for registering Please refresh the page or navigate to another page on the site to be automatically logged in Please refresh your browser to be logged in
Join our commenting forum
Join thought-provoking conversations, follow other Independent readers and see their replies
Comments