Texas doctors have carried out what is believed to be the world’s first partial skull and scalp transplant to help a man with a large head wound caused from cancer treatment.
MD Anderson Cancer Centre and Houston Methodist Hospital doctors announced on Thursday that they did the operation on May 22, the Associated Press said.
The recipient was Jim Boysen, a 55-year-old software developer from Austin, Texas.
Radiation treatments for a rare cancer left him with an open wound in his head that would not heal. Along with the scalp and skull, he received a new pancreas and kidney to treat lifelong diabetes.
Mr Boysen was preparing to leave the hspital on Thursday with a new kidney, pancreas and scalp and skull grafts. He said he was stunned at how well doctors matched him to a donor with similar skin and colouring.
“It’s kind of shocking, really, how good they got it. I will have way more hair than when I was 21,” he told the AP.
Last year, doctors in the Netherlands said they had replaced most of a woman’s skull with a 3-D printed plastic one. The Texas operation is thought to be the first skull-scalp transplant from a human donor, as opposed to an artificial implant or a simple bone graft.
Mr Boysen had a kidney-pancreas transplant in 1992 to treat diabetes he has had since the age of five and had been on drugs to prevent organ rejection. The immune suppression drugs raise the risk of cancer, and he developed a rare type - leiomyosarcoma.
Radiation therapy for the cancer destroyed part of his head, immune suppression drugs kept his body from repairing the damage, and his transplanted organs were starting to fail. “It was a perfect storm that made the wound not heal,” he said.
Yet doctors could not perform a new kidney-pancreas transplant as long as he had an open wound.
Houston Methodist, which has transplant expertise, partnered on the venture. It took 18 months for the organ procurement organisation, LifeGift, to find the right donor, who provided all organs for Mr Boysen. That donor was not identified.
In a 15-hour operation by about a dozen doctors and 40 other health workers, Mr Boysen was given a cap-shaped, 10-by-10-inch skull graft.
Dr Osama Gaber, director of transplantation at the Methodist Transplant Centre, said: “I'm glad the donor family had the generosity and insight to approve us doing this....to get through their grief and approve the donation of this tissue besides the organs.”
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