If Chesterfield are to reach their first FA Cup final, they will have to overcome the Premiership's bottom club, Middlesbrough, in the semi-finals.
Despite the difference in status, they have one thing in common. Neither Middlesbrough or the Second Division club has been this far in this competition.
Chelsea, beaten semi-finalists last season, and Wimbledon, who meet in the other semi, have won the Cup once each.
FA CUP, semi-final draw; Wimbledon v Chelsea, Middlesbrough v Chesterfield.
Matches to be played on Sunday 13 April.
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