Spurs have won the two previous derbies, and a win at the Emirates would secure three successive victories over the Gunners for the first time since October 1974.
However, Mikel Arteta’s side responded in midweek as goals from Martin Odegaard, Gabriel and Mohamed Elneny gave Arsenal a much-needed 3-1 win in the first leg of their Europa League tie at Olympiakos.
Here is everything you need to know:
When is it?
The fixture will kick-off at 4:30pm at the Emirates Stadium.
How can I watch it?
The match is live on Sky Sports Premier League and Main Event with coverage starting from 4pm.
What is the team news?
Arsenal have no injury issues ahead of the North London Derby after Emile Smith Rowe returned to the bench for the win in Greece.
Giovani Lo Celso is out with a back problem, but Harry Kane is expected to play. The England captain scored twice against Dinamo Zagreb on Thursday but was seen icing his knee after being substituted.
Arsenal: Leno, Cedric, Luiz, Gabriel, Tierney, Xhaka, Partey, Smith Rowe, Odegaard, Saka, Lacazette
Tottenham: Lloris, Doherty, Sanchez, Alderweireld, Reguilon, Hojbjerg, Ndombele, Lucas, Bale, Son, Kane
While Arsenal have improved lately, Spurs manager Jose Mourinho has lost just twice in 22 clashes with the Gunners. Both sides will have chances, and I doubt this stays goalless. 2-2 draw.
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