The Gunners fell to a 1-0 defeat against Everton last weekend, before Chelsea’s victory over West Ham saw Unai Emery’s men fall out of the Champions League places.
The fixture is one of four remaining away games for Arsenal, who are yet to keep a clean sheet on the road this season in the league.
Watford also have a lot to play for during the latter stages of the season, having reached the FA Cup final after coming from behind to beat Wolves 3-2 in the semi-final at Wembley last weekend.
The Hornets are also involved in a four-team race to finish in seventh, which may end up being a possible Europa League spot.
What time does it start?
Watford vs Arsenal kicks off at 8pm (GMT).
Where can I watch it?
The match will be shown live on Sky Sports Premier League and Main Event from 7pm. Sky Sports subscribers can also watch the match via the Sky Go app.
The match will also be available on Now TV by grabbing a day pass for just £7.99
Highlights will be shown at 9:30am on Tuesday on Sky Sports Premier League.
Watford: Foster: Femenia, Mariappa, Cathcart, Holebas: Doucoure, Capoue, Hughes, Pereyra: Gray, Deeney
Arsenal: Leno: Mustafi, Koscielny, Monreal: Maitland-Niles, Torreira, Ramsey, Kolasinac: Ozil, Iwobi, Lacazette
Arsenal 2 (Catchart og, Ozil) Watford 0, Premier League, September 2018
Arsenal 3 (Mustafi, Aubameyang, Mkhitaryan) Watford 0, Premier League, March 2018
Watford 2 (Deeney pen, Cleverley) Arsenal 1 (Mertesacker), Premier League, October 2017
Arsenal 1 (Iwobi) Watford 2 (Kaboul, Deeney), Premier League, January 2017
Watford 1 (Pereyra) Arsenal 3 (Cazorla pen, Sanchez, Ozil), Premier League November 2016
Watford to win: 21/10
Arsenal to win: 5/4
Watford 2-1 Arsenal
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