Support for Ukraine and future relations with the EU are among the issues he will be grilled on as he faces his first monthly question time as foreign secretary in the House of Lords.
The situation in Belarus and Afghanistan is also to be raised with the Cabinet minister by peers.
Lord Cameron cannot appear before the House of Commons because he is not an elected MP, which has fuelled concerns about democratic accountability. Foreign Office minister Andrew Mitchell will deputise for him in the Commons, while he will answer questions in the upper chamber each month.
The first question on Ukraine was due to be asked by Lord Robertson of Port Ellen, a former Nato secretary general.
Lord Cameron was also expected to be pressed over the future UK relationship with Brussels by former Labour MP Baroness Hoey, a Brexit supporter who sits as a non-affiliated peer.
The return of the former prime minister as foreign secretary and his call for the UK to be a “friend, a neighbour and the best possible partner” for the EU has caused unease among some Brexiteers.
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