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At least 45 refugees drowned in a shipwreck and more than 2,000 have been rescued from boats in the Mediterranean, the third major incident in as many days.
In the last week, around 14,000 people have been taken off flimsy vessels, the United Nations and Italian coastguard said.
Hundreds may have drowned, according to survivors and boat crews, though there are no official estimates of total casualties.
The Italian Navy ship Vega pulled around 135 people from a "half-submerged" rubber boat in one of 17 operations on Friday. The Vega recovered 45 bodies and is still searching for the missing people.
Show all 27 1 /27Refugee crisis - in pictures Refugee crisis - in pictures A child looks through the fence at the Moria detention camp for migrants and refugees at the island of Lesbos on May 24, 2016.
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Refugee crisis - in pictures Ahmad Zarour, 32, from Syria, reacts after his rescue by MOAS (Migrant Offshore Aid Station) while attempting to reach the Greek island of Agathonisi, Dodecanese, southeastern Agean Sea
Refugee crisis - in pictures Syrian migrants holding life vests gather onto a pebble beach in the Yesil liman district of Canakkale, northwestern Turkey, after being stopped by Turkish police in their attempt to reach the Greek island of Lesbos on 29 January 2016.
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Refugee crisis - in pictures Refugees flash the 'V for victory' sign during a demonstration as they block the Greek-Macedonian border
Refugee crisis - in pictures Migrants have been braving sub zero temperatures as they cross the border from Macedonia into Serbia.
Refugee crisis - in pictures A sinking boat is seen behind a Turkish gendarme off the coast of Canakkale's Bademli district on January 30, 2016. At least 33 migrants drowned on January 30 when their boat sank in the Aegean Sea while trying to cross from Turkey to Greece.
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Refugee crisis - in pictures A general view of a shelter for migrants inside a hangar of the former Tempelhof airport in Berlin, Germany
Refugee crisis - in pictures Refugees protest behind a fence against restrictions limiting passage at the Greek-Macedonian border, near Gevgelija. Since last week, Macedonia has restricted passage to northern Europe to only Syrians, Iraqis and Afghans who are considered war refugees. All other nationalities are deemed economic migrants and told to turn back. Macedonia has finished building a fence on its frontier with Greece becoming the latest country in Europe to build a border barrier aimed at checking the flow of refugees
Refugee crisis - in pictures A father and his child wait after being caught by Turkish gendarme on 27 January 2016 at Canakkale's Kucukkuyu district
Refugee crisis - in pictures Migrants make hand signals as they arrive into the southern Spanish port of Malaga on 27 January, 2016 after an inflatable boat carrying 55 Africans, seven of them women and six chidren, was rescued by the Spanish coast guard off the Spanish coast.
Refugee crisis - in pictures A refugee holds two children as dozens arrive on an overcrowded boat on the Greek island of Lesbos
Refugee crisis - in pictures A child, covered by emergency blankets, reacts as she arrives, with other refugees and migrants, on the Greek island of Lesbos, At least five migrants including three children, died after four boats sank between Turkey and Greece, as rescue workers searched the sea for dozens more, the Greek coastguard said
Refugee crisis - in pictures Migrants wait under outside the Moria registration camp on the Lesbos. Over 400,000 people have landed on Greek islands from neighbouring Turkey since the beginning of the year
Refugee crisis - in pictures The bodies of Christian refugees are buried separately from Muslim refugees at the Agios Panteleimonas cemetery in Mytilene, Lesbos
Refugee crisis - in pictures Macedonian police officers control a crowd of refugees as they prepare to enter a camp after crossing the Greek border into Macedonia near Gevgelija
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Refugee crisis - in pictures A refugee tries to force the entry to a camp as Macedonian police officers control a crowd after crossing the Greek border into Macedonia near Gevgelija
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Refugee crisis - in pictures Refugees are seen aboard a Turkish fishing boat as they arrive on the Greek island of Lesbos after crossing a part of the Aegean Sea from the Turkish coast to Lesbos
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Refugee crisis - in pictures An elderly woman sings a lullaby to baby on a beach after arriving with other refugees on the Greek island of Lesbos after crossing the Aegean sea from Turkey
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Refugee crisis - in pictures A man collapses as refugees make land from an overloaded rubber dinghy after crossing the Aegean see from Turkey, at the island of Lesbos
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Refugee crisis - in pictures A girl reacts as refugees arrive by boat on the Greek island of Lesbos after crossing the Aegean sea from Turkey
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Refugee crisis - in pictures Refugees make a show of hands as they queue after crossing the Greek border into Macedonia near Gevgelija
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Refugee crisis - in pictures People help a wheelchair user board a train with others, heading towards Serbia, at the transit camp for refugees near the southern Macedonian town of Gevgelija
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Refugee crisis - in pictures Refugees board a train, after crossing the Greek-Macedonian border, near Gevgelija. Macedonia is a key transit country in the Balkans migration route into the EU, with thousands of asylum seekers - many of them from Syria, Afghanistan, Iraq and Somalia - entering the country every day
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Refugee crisis - in pictures An aerial picture shows the "New Jungle" refugee camp where some 3,500 people live while they attempt to enter Britain, near the port of Calais, northern France
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Refugee crisis - in pictures A Syrian girl reacts as she helped by a volunteer upon her arrival from Turkey on the Greek island of Lesbos, after having crossed the Aegean Sea
EPA
Refugee crisis - in pictures Refugees arrive by boat on the Greek island of Lesbos after crossing the Aegean sea from Turkey
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Refugee crisis - in pictures Beds ready for use for migrants and refugees are prepared at a processing center on January 27, 2016 in Passau, Germany. The flow of migrants arriving in Passau has dropped to between 500 and 1,000 per day, down significantly from last November, when in the same region up to 6,000 migrants were arriving daily.
The warmer weather and calmer seas have led to a surge in the number of people trying to cross from Libya, the coastguard said.
Dozens of refugees are feared to have died when a boat sank off the Libyan coast on Thursday, when 4,000 were rescued in 22 separate operations.
Moment huge ship full of refugees capsizes A day before, at least five died when a wooden fishing boat carrying refugees capsized .
Photographs from the Italian Navy showed the blue fishing boat rocking precariously before capsizing and sending the refugees into the sea.
Refugees, many of whom do not know how to swim and do not have life jackets, pay hundreds or thousands of dollars to make the crossing from Libya to Italy.
In 2014 and 2015, more than 320,000 refugees arrived on Italian shores by boat and an estimated 7,000 died in the Mediterranean as they sought to reach Europe, according to the International Organisation for Migration.
The IOM said on Friday it estimates around 1,475 people have died in the Mediterranean this year.
Additional reporting by Reuters
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