Manchester City will be without Yaya Toure as they look to get back to winning ways.
Manuel Pellegrini, whose team have lost their last two Premier League matches after winning each of their first five, brings David Silva back into the line-up after he missed the defeat at Tottenham.
The Chilean has also decided to drop Bacary Sagna to the bench in place of Pablo Zabaleta, who has not played for City since the final day of last season.
For Newcastle, Steve McClaren has been forced into one change, with Yoann Gouffran coming in for Jack Colback, the midfielder picked up an injury during the 2-2 draw with Chelsea.
Manchester City: Hart, Zabaleta, Otamendi, Mangala, Kolarov, Fernando, Fernandinho, Silva, Sterling, De Bruyne, Aguero
Subs: Caballero, Demichelis, Sagna, M.Garcia, Navas, Bony, Iheanacho
Newcastle: Krul; Janmaat, Mbemba, Coloccini, Mbabu; Sissoko, Anita, Gouffran, Wijnaldum; Perez, Mitrovic
Subs: Elliot, Lascelles, Williamson, Tiote, Thauvin, de Jong, Cisse
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