Arsenal could have up to 11 players missing for the match against Stoke on Saturday.
In a worst-case scenario, Arsene Wenger will be missing his first and second-choice goalkeepers, meaning Emiliano Martinez will start in goal again, and three defenders.
The Physio Room keep track of injuries in the Premier League and show that the Gunners are the worst hit of all the 20 teams.
However, the website shows a worst-case outlook of the teams, and at least five of Arsenal's injured players - Tomas Rosicky, Laurent Koscielny, Kieran Gibbs, Yaya Sanogo and Wojciech Szczesny - could play at the Britannia.
Manchester United are also struggling through an injury crisis with up to nine players missing for the match against Southampton although, again, that is a worst-case view.
Wayne Rooney, for example, is among those named among the casualties but he could play at St Mary's on Monday night.
Newcastle continue to struggle with injuries, they too could have up to nine out when they visit Stamford Bridge for the early game on Saturday.
Liverpool may have seven players out, with Daniel Sturridge and Mario Balotelli still on the sidelines, but Jose Enrique, Mamadou Sakho and Philippe Coutinho could return.
At the other end of the scale Chelsea are relatively injury free, with only Ramires, Nathan Ake and Gary Cahill having question marks over their fitness, although Nemanja Matic is suspended.
Swansea are in the best shape with just one player a doubt and Federico Fernandez may even be fit enough to face West Ham.
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